Drug discovery > Target Discovery Products & Reviews

Bioinformatics and Protein Array Services

Profiling against cancer antigens. Using the CTA Protein Array, Sengenics can quantify autoantibodies against more than 200 clinically relevant cancer testis antigens. These are tumor antigens normally expressed in germ cells but not in adult somatic tissues. In cancers, this regulation can be disrupted, resulting in CTA expression in tumors. The CTA array is ideal for research related to cancer immunotherapy.

Cancer drug screening and discovery. The OncoRex p53 Cancer Array provides a biologically relevant screening tool since all p53 variants are correctly folded and functional using the patented KREX ® protein folding technology. Using the array, Sengenics can screen your therapeutic antibodies and protein binding compounds against more than 100 p53 wildtype and mutant variants by measuring their impact on DNA binding as a func…

The i-Ome Discovery Protein Array uses the patented KREX® protein folding technology to enable accurate and reproducible profiling of patient samples against more than 1800 carefully selected full-length, properly folded proteins. Curated content focused on known and potential autoantigens helps facilitate biomarker discovery with significantly lower false discovery rates and smaller sample sizes than other technologies. The…

Autoimmune disease autoantibody screening. Using the Pan-Autoimmune Protein Array 1.0, Sengenics can screen autoantibodies against more than 100 clinically relevant antigens in a wide range of autoimmune diseases. The Pan-Autoimmune Protein Array 1.0 service is ideal for focused autoimmune disease research.

LibraryView software is a fast way to analyze large volumes of data for contaminant screening applications. This unique MS/MS software solution offers accurate, efficient library searching, data mining, and compound database management in one easy-to-use platform. High-throughput data analysis in minutes: Screening your chromatograms for hundreds of compounds in hundreds of samples can require endless hours at the computer. Wi…

PeakView software is everything you need for spectral analysis and data interrogation. Process accurate mass, structural interpretation, and batch analysis within a few clicks.  With PeakView software, mine your data effectively to unravel critical information. Easily review, identify, superimpose, compare samples, and label peaks across scales and with varying intensities in a single spectrum using advanced algorithms that au…

MasterView software is a powerful application that enables you to accurately screen unknown samples against the targeted list of compounds for quick identification, quantitation, and data review from complex mass spec data files. With MasterView software, laboratories can master the speed, power, and accuracy offered by LC-MS/MS technology. You can easily identify unknown compounds with greater confidence, using integrated lib…

A high-resolution mass spectrometry solution that combines powerful MS/MS sensitivity, fragmentation technology, and a step-change in data-independent acquisition.

MarkerView software does the heavy lifting for you to rigorously mine data and provide statistical analysis and visualization of large numbers of samples. MarkerView software is ideal for profiling and comparing the composition within your samples in order to gain valuable insight into any trends within your mass spectral. This post-acquisition analysis software reduces the need for manual intervention empowering you to explor…

Now you can achieve high sensitivity quantitation without sacrificing throughput and robustness with the all-new OptiFlow Quant solution from SCIEX. We open up new possibilities by combining the new easy-to-use OptiFlow Turbo V source and the powerful M5 microLC system. You will gain significant signal-to-noise advantages while avoiding the hassle and complexity of a low flow assay setup.  

When you need to maximize throughput, the MPX 2.0 High Throughput system is what you need. The MPX 2.0 High Throughput system takes advantage of the downtime between injections from your LC and multiplexes two LC systems into one mass spec, doubling your throughput.  

The Turbo V source is considered the gold standard in mass spec ionization. The patented orthogonal design delivers outstanding ionization efficiency and robustness across many applications, covering flow ranges of 5 uL/min to 3 mL/min. This renowned ion source acts as the foundation on which SCIEX mass spec systems are built and serves as the inspiration for many of the ion sources that followed.  

The IonDrive™ Turbo V source increases the capacity of the legendary Turbo V source, maintaining the simple orthogonal design but with higher capacity heaters and a wider sweet spot for enhanced sensitivity.

The robustness and simplicity you’ve come to expect from a traditional analytical flow can now be experienced in your high-sensitivity microflow and nanoflow analyses. We have made this possible with standard size finger-tight fittings, and a new single-click source interface – allowing you to effortlessly connect your LC, column, and mass spec. The OptiFlow source is equipped with intelligent probe recognition technology t…

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Achieve better insights into biotransformations and impurities

Cloud-based mass spectrometry software

Achieve clarity on your biotherapeutic. Leveraging the latest acquisition techniques and built on a heritage of proven performance, Biologics Explorer software delivers highly accurate and informative workflows for fully characterizing protein biotherapeutics. Reach decisions on the most important critical quality attributes for biopharmaceuticals faster and more confidently.

Real-Time Live Cell Imaging and Analysis System

The Gyrolab® PLBL2 Kit enables rapid quantification of hamster phospholipase B-like 2 (PLBL2) impurities in bioprocess and manufacturing samples of Chinese hamster ovary (CHO) cell-derived monoclonal antibodies (mAbs)

The Gyrolab® Mouse IFN-gamma Kit enables rapid quantification of murine IFN-gamma in serum samples

Sf9 HCP 3G Solution for Gyrolab for the detection of Sf9 host cell protein impurities in bioprocess samples.

E.Coli HCP 2G Solution for Gyrolab enables detection of E. coli HCP impurities in products manufactured by recombinant expression.

The Gyrolab® Mouse IL-6 Kit enables rapid quantification of murine IL-6 in serum samples