Drug discovery > Target Discovery Products & Reviews

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Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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Shotgun metagenomics sequencing

Novogene

Shotgun metagenomic sequencing is designated to sequence the total genomic DNA from environmental samples without the prior isolation and cultivation of individual species. The services are applied for studying the rich genetic repertoire of microbial communities with taxonomy information, and for studying system evolution, gene function, and metabolic network of environmental microorganisms.

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Epigenome sequencing

Novogene

Novogene provides Whole Genome Bisulfite Sequencing (WGBS), Reduced Representation Bisulfite Sequencing (RRBS), Chromatin Immunoprecipitation Sequencing (ChIP-seq), RNA Immunoprecipitation Sequencing (RIP-seq), and Assay for Transposase-Accessible Chromatin Sequencing (ATAC-seq), tailored for both bulk and single-cell samples.

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Flare™

Cresset

Flare™ is a ligand-based and structure-based drug design platform. Through high-resolution 3D visualization and in-depth analysis of target structures and potential ligands, Flare enables users to optimize and prioritize new molecules efficiently and effectively.

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Flare™ FEP

Cresset

Flare™ FEP enables research chemists to refine docking results, making the right structure-based design choices for lead optimization with confidence.

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Spark™

Cresset

Spark™ is a powerful scaffold hopping and bioisosteric replacement solution that generates highly innovative ideas for your project to explore chemical space and escape IP and toxicity traps.

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Blaze™

Cresset

Blaze™ is an advanced virtual screening platform enabling you to dramatically increase your wet screening hit rate at a fraction of the cost.

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Discovery CRO

Cresset

Cresset Discovery is a premier computational chemistry CRO with a proven track record delivering high impact drug discovery projects. From ideation to synthesis and biological results, their expert CADD scientists are the best at what they do. Working alongside you from the ground up, they apply the best in silico techniques, and give expert advice and guidance, to accelerate your assets through the pipeline.

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eXTReme™ FoilSeal™ Microplate Sealing Film for PCR and Long-Term Storage, Light Sensitive Assays & Robotics

Excel Scientific, Inc.

A 48 um soft non-permeable aluminum foil sealing film with 30 um layer of strong acrylic adhesive. FoilSealTM sealing foils remove cleanly from plate surfaces with no adhesive stringing, residue or contamination. Each sealing foil measures 78.3 x 129 mm and offers sufficient sealing area for all plate types (e.g. flat top and raised-rim). Chamfered corners result in no plate overhang for robotics applications. Features one end…

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ThermalSeal™ RTS, Optically Clear, Silicone Adhesive Microplate Sealing Film for Real-Time PCR

Excel Scientific, Inc.

The encapsulated silicone adhesive is non-tacky until pressed against the sealing surface, at which time adhesive is released only in sealing areas to form the strongest available heat-resistant seal around each well on the plate. Adhesive on non-sealing areas of the film, such as directly over sample wells, remains encapsulated and inert. Excel ThermalSeal RTS films are sized to fit within the edges of raised-rim 96-well plat…

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X-Pierce™ Microplate Sealing Film for Automation

Excel Scientific, Inc.

X-PierceTM sealing films are 89 µm thick vinyl with a 18 µm thick adhesive layer, designed for temporary protection from contamination and evaporation for samples in 96-well plates. A precut "X" over each well creates four flaps that easily bend downward when pushed by a robotic probe or pipet tip, allowing sample access without coring or adhesive fouling. A thin adhesive layer and special hairline cuts separating the X-Pierce…

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AeraSeal™ Microplate Sealing Film for Cell & Tissue Culture

Excel Scientific, Inc.

A 140 µm thick hydrophobic porous rayon sealing film including medical-grade adhesive for tissue culture plates, bio-blocks, and 96-well plates where gas exchange is necessary for cell or bacterial growth. AeraSeal sealing films minimize cross-contamination, spillage and evaporation. They allow uniform air and CO2 exchange for all wells, unlike plate lids which favor exchange for wells near the plate edges. Dimensions: 82.6 by…

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SealMate™ Starter Kit with SealPlate Elisa/Storage Film

Excel Scientific, Inc.

Excel Scientific's unique SealMate™ system provides a convenient new method for sealing standard-format microplates with adhesive films. The system includes a molded polypropylene dispenser with a hinged “clamshell” design and sealing films supplied in a novel sheeted-roll configuration.Features:environmentally friendly green product: no protective backing to remove and discardconvenient, easy film application for microplatest…

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SealMate™ Starter Kit with AeraSeal Breathable Film

Excel Scientific, Inc.

Excel Scientific's unique SealMate™ system provides a convenient new method for sealing standard-format microplates with adhesive films. The system includes a molded polypropylene dispenser with a hinged “clamshell” design and sealing films supplied in a novel sheeted-roll configuration.Features:environmentally friendly green product: no protective backing to remove and discardconvenient, easy film application for microplatest…

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