Drug discovery > Target Discovery Products & Reviews

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Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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Single cell sequencing

Novogene

Single cell RNA sequencing uncovers the complexity of cellular diversity to employ the study of unusual cell types, cell-lineage associations, and samples of heterogeneous nature with 10x Genomics technology.

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Long-read sequencing

Novogene

Long Read Sequencing (LRS) service employs cutting-edge technologies such as Oxford Nanopore and PacBio platforms for decoding complex genomes, completing transcriptomes, exploring metagenomes, and investigating structural variations with unmatched precision.  

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Shotgun metagenomics sequencing

Novogene

Shotgun metagenomic sequencing is designated to sequence the total genomic DNA from environmental samples without the prior isolation and cultivation of individual species. The services are applied for studying the rich genetic repertoire of microbial communities with taxonomy information, and for studying system evolution, gene function, and metabolic network of environmental microorganisms.

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Epigenome sequencing

Novogene

Novogene provides Whole Genome Bisulfite Sequencing (WGBS), Reduced Representation Bisulfite Sequencing (RRBS), Chromatin Immunoprecipitation Sequencing (ChIP-seq), RNA Immunoprecipitation Sequencing (RIP-seq), and Assay for Transposase-Accessible Chromatin Sequencing (ATAC-seq), tailored for both bulk and single-cell samples.

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Flare™

Cresset

Flare™ is a ligand-based and structure-based drug design platform. Through high-resolution 3D visualization and in-depth analysis of target structures and potential ligands, Flare enables users to optimize and prioritize new molecules efficiently and effectively.

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Flare™ FEP

Cresset

Flare™ FEP enables research chemists to refine docking results, making the right structure-based design choices for lead optimization with confidence.

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Spark™

Cresset

Spark™ is a powerful scaffold hopping and bioisosteric replacement solution that generates highly innovative ideas for your project to explore chemical space and escape IP and toxicity traps.

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Blaze™

Cresset

Blaze™ is an advanced virtual screening platform enabling you to dramatically increase your wet screening hit rate at a fraction of the cost.

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Discovery CRO

Cresset

Cresset Discovery is a premier computational chemistry CRO with a proven track record delivering high impact drug discovery projects. From ideation to synthesis and biological results, their expert CADD scientists are the best at what they do. Working alongside you from the ground up, they apply the best in silico techniques, and give expert advice and guidance, to accelerate your assets through the pipeline.

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ADAM SCC2: Automated Somatic Cell Counter

NanoEntek

ADAM SCC2, a fast, easy and accurate automated somatic cell counter, is composed of fluorescence optic and image analysis software. It can be useful equipment for dairies, smaller labs and veterinary establishments working with somatic cell analysis. It is helpful to the implementation of milk quality control.

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