Separations Products & Reviews

A range of amylose cellulose based enantiomeric selectors, with unique bonding chemistries

Superdex™ 75 Increase 10/300 GL, 5/150 GL, and 3.2/300 are prepacked columns for versatile use in size exclusion chromatography applications. The columns are intended for use in preparative purification as well as for characterization and analysis of proteins with molecular weights between Mr 3000 and 70 000, such as recombinant tagged proteins.

Purchase your Vydac columns for your legacy methods from MAC-MOD

The H-Cell is a two-compartment electrochemical cell used for membrane testing, H2 permeation, or any other experiment where two separate electrode chambers are required. Both compartments can be separated by an ion-exchange membrane.  Thus, any byproduct generated at the counter electrode does not affect the working electrode's behavior and vice versa.

Optimized for AAVs, large proteins, and RNAs/DNAs by SEC-MALS. Narrow-bore for ultimate detection sensitivity when used with a low dispersion (U)HPLC system.

GTxResolve Premier columns batch tested for recovery and resolution of nucleic acids and protein containing samples. With surface technologies and methods optimized for mRNA, LNP and viral vector applications.

GL Sciences' Bio LC Columns "ProteoSil" are tailored HPLC solutions designed specifically for proteomics and the analysis of bio molecules such as proteins, peptides, and nucleic acids. The packing materials used in these columns are crafted from high-purity silica, offering pore sizes of 100Å, 200Å, and 300Å. They are available in multiple configurations, including reversed phase, HILIC, and size exclusion columns.

Size exclusion chromatography columns: for high-resolution purification and analysis of mAbs and proteins.

SEC Analytical Column optimized for MALS. Narrow-bore for standard proteins in aqueous solvents.

GTxResolve Premier columns batch tested for recovery and resolution of nucleic acids and protein containing samples. With surface technologies and methods optimized for mRNA, LNP and viral vector applications.

The new Finnigan Pocket Surveyor software providing local instrument control for new and existing Finnigan Surveyor HPLC Systems. The software operates on a handheld computer running the popular Windows Pocket PC 2002 O/S and offers chromatographers the ability to connect directly to their Surveyor quaternary gradient pump and/or variable wavelength detector.   In addition to individual module control, the Finnigan Pocket Sur…

Software Platform for the Characterization of Polyolefins.

High Temperature Gel Permeation Chromatograph for Polyolefin Analysis.

Acclaim™ Trinity P1 is a unique, high-efficiency, silica-based column designed for pharmaceutical applications such as simultaneous separation of pharmaceutical drug substances and their counterions. his new column, based on nanopolymer silica hybrid (NSH) technology, provides multiple retention mechanisms including reversed-phase, anion-exchange, and cation-exchange. As a result, its selectivity can be easily opti…

The Thermo Scientific Acclaim™ Explosives E1 (5 µm) and E2 (5, 3 and 2.2 μm) silica-based reversed-phase columns are designed to resolve all 14 explosives listed in EPA SW-846 Method 8330: Nitroaromatics and Nitramines by HPLC. Their unique chemistries deliver superior resolution with complementary selectivities. The E1 is recommended for use as a direct replacement for ODS columns for the primary analysis.The E2 may be used a…

High-Resolution Separation of Proteins and Peptides The Acclaim® 300 features 3 µm silica particles for rapid analysis of complex protein digests. The Acclaim 300’s stable bonding make these columns compatible with a wide variety of applications, including LC/MS methods.Manufacture of these columns starts with ultrapure silica that contains minimal concentrations of metal contaminants, minimizing the tailing effects of residua…

The DNASwift™ SAX-1S is a strong anion-exchange column that provides exceptionally high resolution for the purification of oligonucleotides.The exceptionally high resolution provides superior purity and yields compared to other ion-exchange or reversed-phase columns available. The DNASwift column is ideal for therapeutic and diagnostic research, which have very high purity and yield oligonucleotides purification requirements.T…

The Thermo Scientific Acclaim™ PepMap™ 100 C18 column sets the benchmark in peptide separation.The PepMap100 C18 column is available in 3 or 5 µm particle sizes, with 100 Å pore sizes, and in nano, capillary, and micro formats. nanoViper fingertight fittings allow for easy column installation.Column Details: Chemistry: C18 Particle Size: 3, 5 μm Pore Size: 100 Å Length: 5, 15, 25, 50 mm ID: 75, 300 μm, 1.0 mm

Acclaim™ PepMap300 C18 is used for the separation of larger peptides and proteins.It is available in 5 µm particle sizes, with 300 Å pore sizes, and in nano, capillary, and micro formats.Column Details: Chemistry: C18 Particle Size: 3, 5 μm Pore Size: 100, 300 Å Length: 5, 15 mm ID: 75, 300 μm, 1 mm

MAbPac™ SCX-10 Columns for the High-Resolution Separation and Analysis of Monoclonal Antibody VariantsThe Thermo Scientific™ MAbPac™ SCX-10 column line has been expanded to include 3 and 5 μm particle sizes for fast, high-resolution analysis as well as rapid separation (RS) columns for bio-UHPLC separations. These smaller-particle-size columns provide the same high resolution as the 10 μm columns, but with…

High-Resolution, Strong and Weak Anion-Exchange Columns for the Separation of ProteinsThe ProPac® SAX-10 is a nonporous, strong anion-exchange column (quaternary amine functional group). The ProPac WAX-10 column is a weak anion exchanger (tertiary amine functional group). Both are based on a nonporous core particle that provides pressure stability. A hydrophilic layer prevents unwanted secondary interactions and a grafted anio…

Strong and Weak Cation-Exchange Columns for High-Resolution Separation of Proteins and MAbsThe Thermo Scientific ProPac™ SCX column line has expanded to include the next generation ProPac SCX-20 column. This column provides unequalled high resolution of protein variants.ProPac SCX-10 and WCX-10 strong and weak cation-exchange columns are based on a nonporous core particle that results in high-efficiency peaks and high-resoluti…

For Hydrophilic Anionic Protein SeparationsThe ProPac® PA1 column supports the analysis and purification of hydrophilic anionic proteins and peptides. Proteins and peptides that are highly cationic (e.g., those with very high isoelectric points) may be resolved on this column, but some may exhibit substantial binding to the column.ProPac® PA1 Protein and Peptide Column Features: Good for hydrophilic anionic proteins and pepti…

Hydrophobic Interaction Chromatography Columns for the Separation of Large BiomoleculesHydrophobic Interaction Chromatography separates biomolecules in a decreasing salt gradient, based on differences in surface hydrophobicity. This method preserves the biological activity of proteins. The HIC separation mechanism is complementary to those of ion-exchange and gel filtration chromatography.The ProPac® HIC-10 column is a high-re…

ProSwift™ ConA-1S Affinity Column for Glycan, Glycopeptide and Glycoprotein Enrichment and Purification The ProSwift ConA-1S affinity monolith column is unsurpassed for fast, highly efficient enrichment and purification of Concanavalin A (Con A) binding glycans, glycopeptides, and glycoproteins from complex samples.The HPLC- compatible ProSwift ConA-1S affinity column maintains the specificity and selectivi…