Drug discovery > Pre-Clinical Development Products & Reviews

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Products, services, reviews and techniques used in lead molecule delivery, formulation and toxicology, using assays and animal models.

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RUO and GMP Leukopaks

BioIVT

BioIVT offers high quality, normal and disease state, fresh mobilized and cryopreserved leukopaks, custom collected or sourced from extensive inventory, featuring a diverse donor pool including over 600 HLA-typed recallable, consented donors near biotech hubs in the US and UK.

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Normal and Disease State Tissue

BioIVT

BioIVT’s extensive, highly characterized, normal and disease-state tissue samples are collected and prepared under strict ethical and QC policies and feature detailed clinical data as well as pathologist verification of disease tissue blocks to help ensure the accuracy of your research. Custom collections or extensive inventory are available from a diverse donor pool or any commercially available species.

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In Vitro ADME-Tox Test Systems

BioIVT

BioIVT is the leading provider of quality, highly characterized, ethically procured ADME research products, featuring custom preparation or extensive ready-to-ship inventory, large lot sizes and expert support.

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Isolated Immune Cells

BioIVT

Isolated immune cells play a crucial role across the stages of drug discovery and development from biomarker and target identification through screening and safety assessment to manufacturing. They can be used to create disease models, cell lines, gene editing techniques and more.

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Clinically-Collected Specimens

BioIVT

BioIVT has the expertise in the processes required for ethical acquisition of biospecimens that cover a wide range of disease states and the protocols needed to produce reliable data. With over 425 IRB-approved clinical sites, BioIVT provides clinical specimens for nearly all disease states.

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Blood, Plasma and Serum

BioIVT

BioIVT supplies high quality, ready to ship or custom plasma, serum, and whole blood—both normal and disease-state—collected from a diverse pool of consented donors under IRB-approved protocols or a wide variety of species.

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Neuroscience Research Specimens

BioIVT

As the world's largest private repository of human cerebrospinal fluid, BioIVT’s Center for NeuroExcellence offers 35,000+ healthy and 113,000+ diseased donor samples allowing for comparative studies and precise control matching. The samples are ethically collected following strict quality standards and feature detailed clinical data and matching blood, plasma, or sera.

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In Vitro ADME/DMPK Studies

BioIVT

With decades of drug metabolism, drug-drug interactions (DDI) and related expertise, BioIVT’s experts can provide you with the right studies to understand the properties and potential risks of your compound when it’s most critical for your program.

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easyPunch STARlet

Hamilton

Consistent, Traceable Sample Card Processing. The easyPunch STARlet provides everything needed for hands-free sample card punching and extraction, along with sample traceability.

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RR120 Web Handling Platform

BioDot Inc.

The RR120 is a moderate to high volume production system designed to continuously print lines, coat/impregnate, inspect and dry rolls of materials. Each process is designed as an optional, separate module allowing users the flexibility to adapt the system to a specific application, multiple applications and throughput requirements. Customization is also available.

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ZX1010 Platform

BioDot Inc.

The ZX1010 platform can be configured with a maximum of 4 AirJet HR, 4 BioJet HR, 4 FrontLine HR, or 4 PolyDrop dispensers. Dispensers are sold separately so each machine can be customized to meet the application needs.

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Cellwriter 960

BioDot Inc.

The dropping process has remained a highly manual technique for years, leaving an automation void between harvesters and microscopes. CellWriter now completes the continuum, by automating the dropping process to deliver quality spread interphase and metaphase nuclei for analysis. Features:Automated Cell DroppingAutomated Probe/DAPI DispensingIntegrated HybridizationImprove Metaphase Spread QualityPerform Up To 8 Assays On One…

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Cellwriter 240

BioDot Inc.

Features:Automated Cell DroppingAutomated Probe/DAPI DispensingIntegrated HybridizationImprove Metaphase Spread QualityPerform Up To 8 Assays On One SlideReduce Reagent CostsRemove The Need For Rubber Cement24 Slide Processing Capability

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AD3220 Aspirate / Dispense Platform

BioDot Inc.

BioDot’s AD3220 system is designed for high-speed aspirating and dispensing applications to glass slides, microtiter plates, membranes or any custom surface. This tabletop platform is ideal for R&D environments, but still provides enough dispense area for pilot scale production. Dispensing technology, number of channels and deck options enable customization to meet multiple application needs.

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CellWriter™S

BioDot Inc.

The CellWriter™ S robotic workstation produces slides for Karyotyping, FISH and FFPE. Utilizing BioDot’s nanoliter dispensing technology (BioJet) with temperature and humidity control, the CellWriter S simplifies and automates the dropping process to efficiently deliver quality spread interphase and metaphase nuclei for analysis. FISHArray™ enables multiplexed FISH assays and eliminates the need for rubber cement when prepari…

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BioJet™

BioDot Inc.

This proprietary, quantitative, non-contact technology couples the BioJet “Drop-on-Demand” valve with a high-resolution syringe pump. The BioJet meters precise amounts of reagent, incorporating the benefits of non-contact dispensing and the ability to program exact drop volumes.

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Raimaker™

BioDot Inc.

The Rainmaker features BioDot’s proprietary non-contact piezoelectric low volume dispensing technology and allows users to select a wide range of volumes as a single drop or high-frequency burst. Liquid volumes, from picoliters to nanoliters, can be dispensed On-the-Fly or in Step-and-Repeat mode. Rainmaker’s On-the-Fly printing supports multiple tip dispensing to discrete locations for true high-speed arraying.

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AD6020 Aspirate / Dispense Platform

BioDot Inc.

The AD6020 combines BioDot’s precision low volume dispensing technologies and a large customizable nest to create a high throughput, multi-channel automated liquid handling workstation. Nests for MTPs and slides are available or the system can be customized for unique spotting surfaces and/or labware. Manufacturing throughput can be optimized through single/dual shuttle nest designs.

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XYZ3210 Dispense Platform

BioDot Inc.

Features:Precision Dispensing - Quantitative dispense volumesFlexibleOptional configurations to have AirJet HR, BioJet HR, FrontLine HR, or PolyDrop dispensersMenu driven operating softwareMagnetic NestFootprint - Small design that can accommodate R&D and manufacturing needsMulti-Mode DispensingLine dispensingDot dispensingSuitable for Lateral Flow, Immunoblot, and Flow Through applications

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