Life sciences encompass a diverse range of scientific disciplines focused on the study of living organisms and their interactions with the environment. From basic life sciences (such as cell biology, genetics, immunology, and microbiology) to applied life sciences (such as disease research, multi-omics, and biotechnology), this broad field explores the fundamental processes of life and drives advancements in disease research, patient care, and our overall understanding of living organisms. Discover the endless possibilities of life sciences and their impact on shaping a healthier and more sustainable world.
RFP -Trap® - use your fluorescence fusion as tag for biochemical studies Curiously RFP, a widely used labeling tag in cell biology, is rarely used for biochemical analyses. This may be due in part to limited RFP antibody availability and specificity as well as co-eluted heavy and light antibody chains that interfere with subsequent analyses. Superior results in a fraction of the time The ChromoTek RFP-Trap® overcomes these pro…
GFP/RFP-Booster – enhance your fluorescent fusion protein ChromoTek’s Booster are very small, highly specific GFP- or RFP-binding proteins covalently coupled to the superior fluorescent dyes from ATTO-TEC. With our Booster you can: • Reactivate • Boost • Stabilize the signals of your fusion proteinsDirectly stain your protein of interest in fixed cells and benefit from the high specificity an small size that are perfect for su…
Chromobodies® - Your perfect reagents for cellular research including High-Content Analysis. Chromobodies are fluorescent nanoprobes suitable for real time analyses of endogenous cellular structures and processes in live cells. Chromobodies® are a novel species of extremely small intracellular antibodies. They are based on the antigen binding domain (VHH) derived from heavy chain antibodies of camelids genetically fused to a f…
Fusion of proteins to Glutathione S-Transferase (GST) of Schistosoma japonicum is a common technique to increase solubility and expression level of a protein. Furthermore, GST-tagged fusion proteins are often used in protein-protein interaction studies. Both approaches require highly specific tools to isolate and detect GST fusion proteins. GST-Trap The GST-Trap is a highly specific and robust GST-binding protein coupled to ma…
DNA methylation was the first epigenetic modification identified and has been intensively studied for more than half a century. By now it is clear that Dnmt1, the major eukaryotic DNA methyltransferase, faithfully maintains genome-wide methylation patterns and plays an essential role in the epigenetic network controlling gene expression and genome stability during development. However, the molecular mechanisms that ultimately…
Proliferating cell nuclear antigen (PCNA) is a homotrimeric ring-shaped protein that encircles DNA and acts as a loading platform for multiple, transiently interacting factors participating in various DNA transactions. PCNA plays a key role in DNA replication, repair, cell cycle regulation, and post-replicative transactions like DNA methylation and chromatin remodeling. All these cellular processes are regulated by a complex n…
Being able to visualize endogenous cellular structures in live cells is key for many high content analyses. The two Chromobodies® of the ChromoTek’s Cell Organelle Toolbox offer a new way to investigate key compartments of the cell non-invasively. Lamin-Chromobody® The new Lamin-Chromobody® is a major breakthrough especially in High-Content Analysis (HCA) as apoptosis assays thus far rely on static endpoint assays. The nucle…
RNA polymerase II features a large carboxyl-terminal repeat domain (CTD) that consists of the consensus heptapeptide Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6-Ser7. Differential phosphorylation in this CTD orchestrates accessibility for various co-factors of the transcription complex. Using the phosphorylation specific antibodies it is now possible to determine specific phosphorylation states. In addition to phosphorylation specific antib…
The VisiTIRF Fluorescence Imaging System from Visitron Systems is the ideal solution for the analysis of finest structures or surfaces. The flexibility of the VisiTIRF system and the use of scientific digital CCD camera systems with optimal resolution, speed and sensitivity allows for the adaptation of customized application and configuration. For fluorescence illumination Visitron use solid state lasers or laser diodes . The…
The DH-40iL Microincubator is designed for imaging live cells under constant temperature and atmospheric conditions. This versatile incubation system enables high resolution image analysis, fluorescence microscopy, and time-lapse imaging studies while accommodating both upright and inverted microscopes. Designed to provide complete environment control for either the Series 40 open bath chambers or 35 mm cell culture dishes. E…
The Bold Line Top Stage Incubator H301 is the latest release from OKOLAB in terms of Top Stage incubation. It delivers superior temperature stability, humidity, CO2 and Oxygen control in a fully integrated fashion. The Bold Line Top Stage Incubator H301 Equipment: Incubating Chamber: fits in the microscope stage and holds the specimen. It is equipped with heated glass lid and Temperature and Humidity sensors. T Unit: Bo…
The Water Jacket Incubator provides superior incubation stability above and below room temperature. Water is pumped from a water bath into the base plate and into the lid, which are both Water Jackets. Temperature Control Mechanism Temperature is directly measured inside a reference Petri-dish and is controlled by circulating water from a water bath into the Water Jacket Chamber. The Temeprature Controller reads the temperatur…
UNO-PLUS All-in-one single specimen incubator with the size of a Multi Well plate. UNO-PLUS Features: All-in-one temperature/humidity/CO2 incubator Top Stage Incubator with the footprint of a Multi Well Plate Fits in any XY stage, with the additon of the Multi Well Plate holder (supplied by the stage manufacturer or by Okolab) Specimen holders for #1 35mm dish, #1 glass slide or #1 chambered coverglass Heated Glass Cov…
This entry-level instrument utilizes ratio beam optics to give exceptional stability for a host of applications including photometry, and offers full scanning capabilities. Routine analyses are readily carried out using the simple-to-use photometry, wavelength scan, and time scan modes. The UV-Visible Ratio-Beam Spectrophotometer U-5100 also features an eco-friendly design using an ultra long-life pulsed Xe lamp and easy opera…
The S-3700N features an ultra large specimen chamber and stage to allow observation of specimens at diameters up to 300mm. Hitachi Variable Pressure SEM (VP-SEM) series have been received with high reputation from customers around the world. They feature low vacuum observation method (6 – 270 Pa) which enables observation of non-conductive samples like electronic components, and water containing samples such as cultured cells,…
The LaChromUltra® U-HPLC System, in combination with the TQ Detector, provides unmatched quantitative analysis and characterization capabilities. Features • Seamless integration of the U-HPLC system and the TQ Detector with Empower™ 2 control • Performs SIR, MRM, Product, Precursor, and Neutral Loss Scans on the U-HPLC timescale • Equipped with dual ESI/APCI source as standard, with optional APPI available • 20 ms polarity swi…
Hitachi offers the sleek HT7700 for maximum performance and productivity. The radical design incorporates the ergonomics and user friendliness of a SEM with advanced automation, resolution and analytical capabilities of a TEM. Imaging is completely digital – you won’t find a viewing or projector chamber - and Hitachi’s EMIP-SP database software automatically catalogues your single frame and montaged images. The turbopump evacu…
The HD-2700 is the top-of-the-range STEM featuring optional spherical aberration correction developed in collaboration with CEOS GmbH ot offer significantly improved resolution and analytical sensitivity. By correcting the spherical aberration resolution of less than 0.1 nm can be achieved in dark-field STEM mode. The Cs corrector is field retrofittable for any HD-2700 system that was originally ordered without the Cs correcto…
The HF-3300 300 kV FE TEM is a powerful analytical and high resolution TEM/STEM with inherent high beam brightness, high coherence, high energy resolution, and Hitachi unique functions! Features • High energy-resolution and high beam current • Parallel nanobeam electron diffraction for high precision stress analysis • Spatially-resolved EELS for instant multipoint compositional and chemical binding state analyses • Double-bipr…
The Hitachi NB5000 FIB-SEM integrates a superior 40kV Ga ion FIB column with an ultra-high-resolution Schottky FE-SEM. Like all our products, all components have been designed with consideration of the total system performance. This results in exceptional stability, milling performance and resolution, allowing e.g. automated mill-and-monitor operations for 3D reconstructions with slicing steps down to 5nm. NB5000 incorporate…
The Hitachi IM4000 Ar Ion Milling System offers two milling configurations available in a single instrument: cross section cutting and wide-area sample surface fine polishing. The new Ar ion gun design, with increased milling rate (300µm/h for Si), affords reduced cross section processing times by as much as 65%. For added convenience, the IM4000 sample stage unit can be removed for specimen setting and cross section edge fine…
The Hitachi HPLC Primaide is designed for long-term, stable operation, and features both high reliability and great durability. It offers tremendous capability for everyday analysis.Based on over 50 years of experience in the development and production of HPLC systems, Hitachi proudly introduces the Primaide. Make the most of your analytical equipment with Hitachi as the “Prime Aide” in your lab! Modules • Primaide 1110 Pump w…
Sample surfaces are inevitably coated with hydrocarbon contamination due to sample preparation or from storage. The ZONE desktop sample cleaner/desiccator gently removes contaminations to reveal the true surface of your specimens. There are Two Models ZoneSEM ZoneSEM's sample holder stage was designed for Hitachi Type I and Type II carriers. Adjustable height and optional holders available. Provides effective cleaning of surfa…
The SU9000 Ultra High Resolution FE-SEM is Hitachi's new premium UHR FE-SEM. It features unique electron optics, with the sample positioned inside a gap of the split objective lens pole piece. This so-called true inlens concept - combined with the next generation of HITACHI's cold field emission technology - guarantees the highest possible imaging resolution (0.4nm @ 30kV, 1.2nm @ 1kV) and stability. To make this resolving pow…
Inductively Coupled Plasma Mass Spectrometer (ICP-MS) The Science of sensitivity Bruker's ICP-MS is famous for its innovative and unique technology and has now been further refined to meet the ever increasing demands of latest application and laboratory requirements. Bruker's aurora M90 continues to be the workhorse for the routine laboratory, now with additional and improved characteristics. In addition to the aurora M90, Bru…
