Drug discovery > Lead Discovery Products & Reviews

Agilent J&W HP-FFAP is designed primarily for the analysis of organic acids, free fatty acids, or samples that require quantitation of acidic impurities. The FFAP stationary phase is modified with acid to provide a very inert column that can accommodate the demanding analysis of acids dissolved in water. 

CP-Wax 52 CB GC columns have lower minimum temperature and a higher maximum temperature than non-bonded polyethylene glycol (PEG) columns due to extensive cross linking, delivering higher resolution of low-boiling-point analytes. With guaranteed reproducibility and excellent temperature stability, CP-Wax 52 CB is ideal for EPA and ASTM methods.

Agilent J&W CP-Sil 88 for Dioxins has a very high polarity and a specific selectivity for dioxin and dibenzofuran separations. The column is supplied with an integrated retention gap to avoid problems with solvent condensation, thus allowing repeated splitless injections without phase deterioration, extending column life. 

Agilent J&W DB-624 is recommended for EPA methods 502.2 and 8021, as well as for fast GC/MS volatiles analysis. It is specifically designed for the analysis of volatile priority pollutants and residual solvents.

Introduce volatile compounds from virtually any sample matrix into your GC or GC/MS. Automatic Leak Check, Priority Sample Positions, and Barometric Pressure Compensation improve uptime and efficiency.

Dependable leak-free capillary connections allow reliable backflush, split flow, heart-cutting, and GC x GC on Agilent 8890 and 7890 GC systems. These devices are low thermal mass, oven mountable, and inert.

GC/MS methods are widely used for forensic toxicology, especially for the screening of large numbers of target compounds in complex matrices. Full-scan EI methods offer many advantages for broad-range screening, such as an unlimited number of targets, full-spectrum identity confirmation, and library searching for identification of non-targets. Technologies such as Capillary Flow Technology backflushing, Deconvolution Reporting…

Based on the Agilent 990 Micro GC, this Natural Gas Analyzer offers fast analyses with with easy-to-use software and the ability to calculate all required physical properties.

 Based on the 7010B Triple Quadrupole GC/MS, Agilent’s Pesticides and Environmental Pollutants GC/MS/MS Analyzer 4.0 with the MassHunter Pesticide & Pollutant MRM Database provides the lowest possible detection and quantitation limits for pesticides residues in complex matrices. 

Based on the 7890 GC and 5977A Series Single Quadrupole Mass Spectrometer, the GC/MS PAH Analyzer is suitable for analyzing poly-cyclic aromatic hydrocarbons in environmental and food samples. 

200A pore size;  available in 2.0, 4.6, 10and 21.2  mm ids, and lengths from 50 - 250 mm. Pursuit columns are ideal for pharmaceutical applications using LC/MS, from analyzing lead compounds and biological samples in drug discovery, to implementing dependable analysis of raw materials and approved drugs in the QC process.  Build on the large 200A pore size silica, high liquid density delivers up to 40% faster separations witho…

600 bar; superficially porous, 2.7 µm particle6; available in 2.1 - 4.6 mm id;  30 - 150 mm lengths. ZORBAX Eclipse Plus columns feature improved silica, special bonding and optimized endcapping that combine to deliver exceptional peak shapes for a wide range of analytes.   Agilent's Poroshell 120 columns have a solid 1.7 µm core and a porous .5 µm outer layer, for a total 2.7 µm particle that delivers high resolution and high…

600 bar; superficially porous, 2.7 µm particle6; available in 2.1 - 4.6 mm id;  30 - 150 mm lengths. ZORBAX Eclipse Plus columns feature improved silica, special bonding and optimized endcapping that combine to deliver exceptional peak shapes for a wide range of analytes.  Agilent's Poroshell 120 columns have a solid 1.7 µm core and a porous .5 µm outer layer, for a total 2.7 µm particle that delivers high resolution and high…

400 bar; available in 2.1 - 4.6 mm id; 30, 50, 75, 100, 150 mm lengths. Manufactured by Agilent to rigorous QC specifications, the ZORBAX family encompasses 5 particle sizes and more than 32 phases, for reliable scalability and transferability from HPLC to UHPLC, from lab to lab and around the world.

Extend-C18 columns incorporate a unique patented bidentate silane, combined with a double-endcapping process that protects the silica from dissolution at high pH - up to pH 11.5. 

Experience the power of analytical compound isolation

The 1260 Infinity II LC System is a robust HPLC that offers the widest choice of modules for analytical HPLC and entry-level UHPLC, delivering the performance, reliability, and robustness you need for highest confidence in your daily results.

The 1260 Infinity II Bio-Inert Pump is a quaternary UHPLC pump that is made of bio-inert material for use in biological and extreme pH applications. This pump enables gradient formation and solvent blending from up to four solvents and operates at pressures up to 600 bar and flow rates up to 10 mL/min.

The 1290 Infinity II Diode Array Detector (DAD) delivers multiple wavelength detection with full spectra at sampling rates up to 240 Hz for ultrafast UHPLC separations. The Max-Light cartridge cell features optofluidic waveguides, which improve light transmission to near 100% efficiency without sacrificing resolution caused by cell dispersions effects. 

The 1260 Infinity II Preparative Autosampler is designed for automated sample handling in routine purification applications. This flow-through vialsampler supports preparative flow rates of 200 mL/min and 600 bar pressure. Increase your daily throughput of purified sample by injecting up to 132 preparative samples with a maximum of 3.6 mL volume.

The 1260 Infinity II Bio-Inert LC is a dedicated solution for analysis of large biomolecules in biological samples, including monoclonal antibody (mAb) and protein analysis. Metal-free components in the sample flow path and the absence of iron and steel in solvent delivery lines ensure the integrity of your biomolecules, minimize unwanted surface interactions, and increase column lifetime.

Conversion of cartridge-based methods to an automation friendly 96-well format has never been easier or faster. The same trusted silica-based sorbents in Bond Elut cartridge products are now available in the streamlined Bond Elut 96-well plates. Bond Elut 96 components are specially formulated to offer superior cleanliness, flow reproducibility, and reliability.

Bond Elut PRS is a strong cation-exchange sorbent that is also relatively high in polarity. With no appreciable degree of hydrophobicity, in nonpolar solvents, PRS is capable of polar and hydrogen bonding interactions. Due to the very low pKa of PRS, it is recommended for weaker cationic species, such as pyridinium compounds.

Agilent has what you need for precise, effective, sample delivery from your GC autosampler. 

Agilent’s Ultra Inert Inlet Liners prevent adsorption and ensure accurate sample transfer onto the GC column through a robust deactivated surface. These liners are recommended for trace level analysis of active analytes. Liners with inert wool retain non-volatiles, prolonging column life and lowering frequency of MS source maintenance.