Drug discovery > Lead Discovery Products & Reviews

Explore your translational research with Crown Bioscience’s comprehensive genomics services—offering PCR/qPCR, next-generation sequencing, and advanced bioinformatics to deliver high-quality, reproducible data for biomarker discovery and drug development.

Automated filtration and filling system designed to accurately and aseptically aliquot bulk product into multiple biocontainer bags or bottles.

A compact benchtop design that incorporates 2 or 10 individually powered, high-output stirring stations which can prepare samples for content uniformity testing up to 90% faster than conventional methods.​

Rainbow is an in-situ, fiber optic probe-based, concentration monitor that measures concentration and changes in concentration in real-time without the need for sampling.

Sirius T3 measures pKa, log P, and the solubility of ionizable drugs and small molecules using sub-milligram quantities of samples.

Pion’s PAMPA high-throughput permeability assay uses a range of membranes to mimic physiologic conditions. It allows you to evaluate the passive permeability of API’s as well as the absorption potential of simple or complex formulations using robust models and protocols in a 96-well format.

The SCISSOR is an in-vitro subcutaneous injection site simulator that provides biopharma scientists insights into the behavior of their sub-Q drug candidates.

From small-scale R&D to large-scale manufacturing, Pion homogenizers deliver exceptional fluid processing for particle size reduction (micronization,) cell disruption, and the creation of stable micro- and nanoemulsions and dispersions. Built for scalability, we make the transition from lab to commercial production seamless. Trusted by pharmaceutical, biotech, cannabis, chemical, and food and beverage manufacturers worldwide.

Biotherapeutics Discovery

Fully automated and integrated platform to purify nucleic acids of the highest yield and purity for downstream applications.

EVOLUTE ABN is an advanced water-wettable polymer-based sorbent that extracts acidic, basic and neutral analytes from biological fluids and other aqueous matrices.

Advanced Polymeric SPE for Acidic Analytes

PhyTip® Gel Filtration columns are unique tools for high throughput micro volume desalting or buffer exchange applications. They represent the only high throughput, automatable, chromatography desalting solution. Unlike standard dialysis, up to 96 samples can be processed at a time in as little time as ~ 30 minutes and in most cases re-concentration is not required at the end. The gel filtration columns are similar to the P…

Never use Sodium Sulfate Again!

PhyTip® Columns offer automated, flexible and scalable solution for biomolecule separation.   In addition to columns for affinity purification, nucleic acid purification and gel filtration, PhyNexus have developed PhyTip columns for ion exchange. In traditional ion exchange chromatography, samples, wash buffers and gradient elution buffers pass through packed columns in one direction. The PhyTip column is able to s…

Previously known as Speed-Vap® IV Automated Solvent Evaporation System

Previously known as SolventTrapSVOC Solvent Recovery System

Complete Validation for PFAS Analysis in Compliance with ISO 2167

Automated sample preparation workstation for high volume samples  

SPE Disks for Water Extraction

The first-class option for Hexane Extractable Material

One single kit to quickly and reliably determine 18 different and clinically relevant steroids with only one extraction process.

Outstanding GMP QC Testing Services offering Bioassays throughout the lifecycle of drug development, to support the release, stability, and in-process testing of your drug.

The ideal device to accurately set and maintain temperatures.

Effective adhesive seal prevents evaporation during reaction and storage Can be removed from plate without leaving any residue Autoclavable (121°C, 20 min.) Certified free of human DNA, DNase, RNase and PCR Inhibitor*1 PCR Film, adhesive Sample can be visually monitored through the transparent film PCR Foil, adhesive Easy to pierce Pipette tip does not become tacky (ideal for automated systems) *1 Certifi…