Products, services, reviews and techniques used in the preliminary investigations of the disease; the cell biology, genetics and protein pathways using tissue culture, cloning and imaging.
Automated, preparative gel electrophoresis systems, used for accurate and reproducible size selection/collection of DNA (or cDNA) fragments, for the preparation of libraries for next generation sequencing (NGS)
The SageHLS provides unique electrophoretic method for purifying high molecular weight DNA. Using a cell suspension input, DNA is extracted and immobilized on an agarose surface. This is followed by an enzymatic-mediated fragmentation and automated DNA size selection and collection. The platform features the HLS-CATCH process which employs Cas9 mediated targeting of specific genome targets up to 400kb in length.
EveryBlot Blocking Buffer provides 5 minute blocking and maximum sensitivity for all western blots regardless of detection method.
Founded in 1954 Vilber are leaders in molecular imaging, having equipped more than 20,000 laboratories worldwide. The latest generation of the E-Box standalone gel documentation system provides exceptional image quality, durability and ease of use.
Founded in 1954 Vilber are leaders in molecular imaging, having equipped more than 20,000 laboratories worldwide. Vilber Fusion blot imaging systems have been used by 3 Nobel prize winners. The latest generation of Fusion systems offer ‘better than film’ sensitivity with user upgradability for multi-colour fluorescence blotting.
The Etaluma Lumascope range provides a unique approach to live cell imaging. These compact and durable systems offer high quality brightfield, phase-contrast and fluorescence imaging. Lumascopes are engineered to withstand the most demanding environments including incubators, hoods and workstations.
Optimized for stem cell culture applications
Sustains 80% activity at 37°C for at least 72 hours
Gibco™ Heat inactivated One Shot FBS-Aliquot-free solution
Gibco™ Specialty One Shot FBS-Aliquot-free solution
Gibco™ Premium FBS-Sera with least risk of BSE and lower viral risk.
Gibco™ Specialty FBS-sera qualified for specialty research
Quadrupole mass spectrometers are the classic measuring instrument for evaluating residual gas composition in a vacuum system.
The iDeal ChIP Kit for Transcription Factors. Diagenode’s iDeal ChIP-seq Kit for Transcriptions Factors is a highly specialized solution for robust ChIP-seq results transcription factors. Unlike competing solutions, our kit utilizes a highly optimized protocol and is backed by validation with a broad number and range of transcription factors. The kit provides high yields with excellent specificity and sensitivity. Adv…
Don’t risk wasting your precious sequencing samples. Diagenode’s validated iDeal ChIP-seq kit for Histones has everything you need for a successful start-to-finish ChIP of histones prior to Next-Generation Sequencing. The complete kit contains all buffers and reagents for cell lysis, chromatin shearing, immunoprecipitation and DNA purification. In addition, unlike competing solutions, the kit contains positive and ne…
Tagmentation is a reaction where an enzyme (a transposase) cleaves DNA and incorporates sequencing adaptors at the ends of the DNA fragments in one step. In our ChIPmentation technology we combine chromatin immunoprecipitation and tagmentation in one streamlined workflow where the tagmentation step occurs directly on chromatin. The TAG Kit for ChIPmentation has been developed for researchers who would like to perform Ch…
Cas9 Nuclease protein NLS, in complex with guide RNA, offers benefits for CRISPR/Cas9 technology over plasmid or mRNA transfection: Off-target mutations rarely occur Prolonged expression of Cas9 increases off-target editing but RNP delivery is naturally transient Transfection/injection is easy Cas9-NLS bypasses transcription and translation by delivering the protein directly The efficiency of the guide RNA in vit…
Perform MeDIP (Methylated DNA Immunoprecipitation) followed by qPCR to estimate DNA methylation status of your sample using 5-methylcytosine antibody. Our kit contains high quality reagents to get the highest enrichment of methylated DNA with an optimized user-friendly protocol. Characteristics Generate highly consistent results with internal controls in 24h Minimize error with many reagents in 1 tube Optimized pu…
Perform MeDIP (Methylated DNA Immunoprecipitation) followed by sequencing to get DNA methylation status of your sample using 5-methylcytosine antibody and magnetic beads. Our kit contains high quality reagents to get the highest enrichment of methylated DNA with an optimized user-friendly protocol. This package contains everything you need from gDNA extraction to library preparation and quality check. It allows you to perfo…
Assessing the genome-wide chromatin accessibility from individual cells provides unique insights of gene expression regulation for a number of fields such as development, oncology, and neurology. Bio-Rad’s SureCell ATAC-seq provides a fast, robust, and sensitive analysis of the epigenome at single-cell resolution. This method is powered by the combination of both Bio-Rad’s droplet-based microfluidic and a hyperactive Tn5 t…
Single-base resolution CpG detection with our popular Premium RRBS kit (internal bisulfite conversion controls included) Latest technology in bisulfite-seq using Illumina sequencers: > 10x coverage per CpG More than 4 million CpGs detected in human samples As little as 100 ng in mammals, birds, fish ,and more Complete end-to-end service: wet lab to bioinformatics for only 550 per sample!
The Infinium MethylationEPIC Array is a genome-wide DNA methylation analysis technique based on bisulfite conversion and Illumina® technology. It allows to quantitatively detect the methylation level of over 850,000 human CpG positions throughout the genome with single nucleotide resolution. Briefly, upon treatment with bisulfite, unmethylated cytosine bases are converted to uracil, while methylated cytosine bases remain…
Integrative or individual analyses for chromatin with ENCODE standards. End-to-end wet lab service and full ChIP-seq analysis Collaborative and customized project design to meet your needs Dedicated in-house expert Integrative epigenomics data analysis and presentation-ready graphs Expert, extensive bioinformatics
