Drug discovery > Basic Research Products & Reviews

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Products, services, reviews and techniques used in the preliminary investigations of the disease; the cell biology, genetics and protein pathways using tissue culture, cloning and imaging.

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High Resolution ChIP-seq Library Prep kit

Diagenode

Diagenode's High Resolution Library Preparation Kit significantly enhances the resolution of transcription factor binding sites to single nucleotide levels.Using an optimized, proprietary protocol using an exonuclease to digest protein-bound DNA from the 5' end to within a few nucleotides of the protein binding site, the precise location of transcription factor-bound DNA can be determined. The High Resolution Library Preparati…

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ACSIA NGSLibPrep Edition

PrimaDiag

ACSIA NGSLibPrep Edition, the solution to automate the libraries preparation for next-generation sequencing. In view of increasing your productivity, avoiding contamination and improving your work efficiency, PrimaDiag created ACSIA NGSLibPrep Edition. It uses our software PrimaControlleur®II and has been designed to allow you to effectively perform your libraries preparation.ACSIA NGSLibPrep Edition allows you to perform 96…

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iDeal Library Preparation Kit

Diagenode

The iDeal Library Preparation Kit reliably converts DNA into indexed libraries for next-generation sequencing, with input amounts down to 5 ng.Our kit offers a simple and fast workflow, high yields, and ready-to-sequence DNA on the Illumina platform. Combine this kit with our iDeal ChIP-seq kit for optimal ChIP-seq results. For library preparation of DNA inputs down to 50 pg, our MicroPlex Library Preparation Kit is an optimal…

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Mapix

Innopsys

Simple, User-friendly, High performance. Mapix is a data acquisition and analysis software for microarray images which combines ease-of-use, user-friendliness and high performance. Mapix has the most up to date requirements to browse data from microarray experiments quickly with a high level of reliability and optimised productivity. Mapix is available for 32 and 64 bit operating systems (Windows, Linux and soon MacOS).…

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Spotlight 200 FT-IR Imaging System

PerkinElmer

Spotlight 200 FTIR Microscope System is a high-performance microscopy platform, designed to generate high-quality, reproducible data from a variety of sample types. The combination of the highly-automated, very easy-to-use system and exceptional sensitivity ensures that quality spectra can be obtained from sample areas down to the accepted diffraction limit of 10 microns. In addition, the Spotlight 200 also has the capability…

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Sepmag Q

Sepmag

For homogeneous and Large Volume separations. Production departments need an efficient and economical process to use batches of several liters, with throughputs high enough to meet demand and avoiding particle losses. Sepmag Q is a biomagnetic separation technology specifically developed to process large batch volumes in nucleic acid separation, protein purification, cell isolation, biocatalysts, therapeutics and diagnostics.…

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CRISPR/Cas9 Monoclonal Antibody

Diagenode

A breakthrough in genome engineering. The CRISPR/Cas9 (CRISPR-associated protein 9 nuclease) system uses a RNA-guided endonuclease technology which allows for inducing indel mutations, specific sequence replacements or insertions and large deletions or genomic rearrangements at any desired location in the genome. In addition, Cas9 can also be used to mediate up- or downregulation of specific endogenous genes or to alter hi…

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TB Green Premix Ex Taq II (Tli RNase H Plus)

Takara Bio

This Takara Bio SYBR Green Master Mix is recommended for real-time PCR (qPCR) when high specificity is critical, because this reagent effectively suppresses amplification of primer-dimers and off-target products. Use this product when primer design has been optimized, but an increase in specificity of the qPCR assay is still needed. SYBR Premix Ex Taq II (Tli RNase H Plus) includes SYBR Green I, a reagent designed for interca…

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iMScope TRIO

Imaging Mass Spectrometry identifies what you see at the molecular level iMScope TRIO transforms your data from just "Observation" to "Analysis". The instrument is a combination of an optical microscope which allows the observation of high-resolution morphological images, with a mass spectrometer which identifies and visualizes the distribution of specific molecules. Superimposing the two images obtained based on these very d…

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CleanLaze

B&W Tek, Inc.

The CleanLaze® spectrum stabilized laser system is a narrow, spectral linewidth laser available in both OEM and end-user configurations. The CleanLaze® spectrum stabilized laser system is a narrow, spectral linewidth laser available in both OEM and end-user configurations. Specifically suited for Raman spectroscopy, it offers a hermetically sealed laser component integrated with a laser and a driver. The compact,rugged packag…

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FAM FLICA® Caspase 1 Assay Kit

Immunochemistry Technologies LLC

Detect caspase-1 activity with the FLICA® Caspase 1 Assay Kit. This in vitro assay employs the green fluorescent inhibitor probe FAM-YVAD-FMK to label active caspase 1 enzyme in living cells or tissue samples. Analyze the fluorescent signal using fluorescence microscopy, a fluorescent plate reader, or by flow cytometry. Caspase 1 (ICE):Members of the mammalian caspase family of cysteinyl aspartate-specific proteases play disti…

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Magic Red™ Caspase 3 & 7 Assay Kit

Immunochemistry Technologies LLC

Magic Red™ Caspase 3 and 7 Assay is a substrate-based fluorescent apoptosis assay that measures DEVDase enzyme activity in living, intact cells. Detection of caspase 3 and 7 activity (DEVDase enzymes) is a reliable method for assessing apoptotic activity in experimental cell populations. The Magic Red™ caspase 3 and 7 fluorogenic substrate, MR-(DEVD)2, is primarily targeted by caspases 3 and 7 of the apoptotic protease casca…

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RetroNectin® Reagent

Takara Bio

Research and Clinical Grade RetroNectin Reagent for Retroviral or Lentiviral Transduction. RetroNectin Reagent for retroviral or lentiviral transduction significantly increases transduction efficiency and results in enhanced gene transfer, especially in suspension and hematopoietic stem cells. RetroNectin Reagent is a chimeric peptide composed of E. coli-derived recombinant human fibronectin fragment that contains three funct…

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Mouse ROSA26 safe harbor gene knock-in kit and clones

GeneCopoeia

Mouse ROSA26 safe harbor gene knock-in kit and clones. ROSA26 (also known as ROSAβgeo26 locus) in mice genome is first found in chromosome 6 in one particular strain of mice-named ROSAβgeo26-expressed β galactosidase from a randomly inserted transgene at high levels uniformly in nearly all tissues examined. This locus expresses one coding transcript and two noncoding transcripts, and only the non-coding transcripts are disrup…

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Flow Cytometer Calibration Beads

Takara Bio

Flow Cytometer Calibration Beads for AcGFP/EGFP and mCherry. Use these beads to calibrate your flow cytometer prior to analyzing cells that express the AcGFP1 or mCherry fluorescent proteins. The AcGFP Flow Cytometer Calibration Beads allow for easy calibration of any flow cytometer with a 488 nm laser line that excites the green fluorescent proteins AcGFP1 (Aequorea coerulescens GFP) and EGFP. [The AcGFP Flow Cytometer Calib…

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Thermo Scientific KingFisher Pure Kits

Thermo Fisher Scientific

The Thermo Scientific KingFisher Pure Kits are specially designed for use with the KingFisher nucleic acid purification system. These optimized reagent kits help you achieve rapid, high-quality results for a variety of applications – with minimal effort. KingFisher Pure Kits are now available for Cell and Tissue DNA, DNA Blood, DNA Plant, Plasmid, RNA Blood, RNA Plant, RNA Tissue, and Viral NA.Key Features: Developed spec…

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PureFlex™ process container film

Merck KGaA, Darmstadt, Germany

Designed to provide strength, flexibility (with maximum resistance to flex-crack), excellent gas barrier performance and inert contact. PureFlex™ Single-use process container films are flexible, robust and chemical resistant materials used in the construction of our single-use process containers, including Mobius® assemblies and NovaSeptum® sterile sampling products.PureFlex film is a high purity, medical grade, coextruded fi…

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CRISPR-Cas9 Custom Services

GeneCopoeia

GeneCopoeia offers complete custom services for CRISPR-Cas9-based targeted genomic modification, including CRISPR design and construction, donor design and construction, functional validations, stable cell line establishment, and transgenic mouse generation. Service Details: Validation Services Donor clone services Stable cell line services Transgenic mouse services Advantages: Fast delivery of CRISPR-Cas9 plasmids…

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U-SPECT4 CT

MILabs BV

By far the best available SPECT resolution and sensitivity on the market. Patented 3D focusing capability for dynamic nuclear microscopy in organs and tumors. Ultra-fast imaging with multi-physiologic gating reveals dynamic processes with unprecedented time resolution, ideal for pharmacokinetic imaging.Patented M5™ collimation satisfies widest range of resolution, sensitivity and FOV needs. High reliability and long life due…

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