Products, services, reviews and techniques used in the preliminary investigations of the disease; the cell biology, genetics and protein pathways using tissue culture, cloning and imaging.
The MethylEdge™ System provides an efficient method to rapidly perform bisulfite conversion with minimal DNA fragmentation, giving you more intact, converted DNA for downstream applications. Start with as little as 100pg of input DNA for those precious, limited samples. Use the MethylEdge™ System with other DNA Methylation Workflow reagents to perform sensitive DNA methylation analysis on many sample types. The rapi…
The VenaT4™ biochip model combines Cellix's proprietary microfluidic flow technology for cell recruitment under shear stress with traditional transwell chamber models. Used to investigate and quantify cell recruitment to various ligands in the presence of chemoattractants contained within the microwells mimicking tissue and / or injury sites. The biochips contain 4 microcapillaries in parallel, each with an embedded microporo…
The FlowCellect™ Human NK Cell Characterization Kit includes three directly conjugated antibodies, Anti-CD3-APC, Anti-CD56-PE, and Anti-CD16 FITC. This three color kit is designed to characterize NK within mixed cell populations. The antibodies provided have been carefully titrated to ensure the ability to accurately measure the expression of all markers simultaneously. Sufficient reagents are provided to perform 25 three-colo…
HORIBA Scientific introduces QExtraTechnology, an anti-reflective multi-layer coating to significantly improve quantum efficiency over a broad spectral range while suppressing undesirable etaloning effects.QExtraTechnology provides outstanding quantum efficiency for experiments which require coverage from UV to NIR while suppressing etaloning effects noticeable at longer wavelengths in basic back-illuminated deep depleted came…
DART® Ion Mobility Spectrometer The new DART® Ion Mobility Spectrometer is a completely integrated benchtop instrument equipped with Resistive Glass technology and improved performance. It provides DART-IMS analysis of solid, liquid or gas analytes quickly and easily for use in homeland security, pharmaceutical or laboratory applications. Sample preparation is easy, and identifiable results can be seen in less than 10s. The…
Identify causal variants from human sequencing data in just hours Rapidly Identify and Prioritize Variants Ingenuity Variant Analysis combines analytical tools and integrated content to help you rapidly identify and prioritize variants by drilling down to a small, targeted subset of compelling variants based both upon published biological evidence and your own knowledge of disease biology. Biological Interpretation of your Var…
SmartFlare Probes work by recognizing specific native RNA sequences within living cells, therefore there are many possible sequences that you could design to recognize your target of interest. Instead of lysed cells, switch to live cells. And while you’re at it, eliminate sample preparation and transfection steps all together. Live cell RNA detection is now possible, in a single incubation step using inert nanoparticle techno…
EZ-Fluo is a non-destructive method that enables you to continue to grow the microorganisms after they have been stained in order to identify them using any standard ID technology.
The labelling of DNA samples used in array comparative genomic hybridisation (aCGH) is a critical step in the experimental process as poor labelling can result in inaccurate data. OGT’s CytoSure Genomic DNA Labelling Kits have been uniquely developed and optimised to enable rapid delivery of high quality results with high signal-to-noise ratios.
OnTarget™ is a powerful, new platform for detection of rare tumor mutations in tissue or plasma. • Detect 100 or more mutations in a single assay, without sample splitting • Quantify mutations present at 0.01% allele frequency and above • Enrich mutations extracted from plasma or FFPE in about 1 hour
Reliable detection of copy number changes and loss of heterozygosity on a single array for haematological malignancies and solid cancers. The CytoSure Cancer +SNP array delivers: ■ Flexible choice of reference sample ■ Confident detection of CNV and LOH on a single array ■ An optimised design allowing identification of key genomic aberrations ■ Cancer-specific tracks enabling fast and easy data generation and interpretation o…
The ideal objective for high quality distortion−free imaging in live cells and tissues – brighter images, accurate 3D morphology
In a variety of scientific applications, phenomena elapse in an instant, leaving no clue to their solution. High-speed video cameras record such moments, enabling visualization through slow-motion replay. This technology is used as an important analysis tool in a variety of fields including materials failure, electric discharge, explosions, and microscopic phenomena. In recent years, such observations have progressed to ever…
The Okolab Objective Heater is made by a flexible heating collar with a built in temperature sensor, which can be easily fastened around the objective with the supplied Velcro tape. The heating collar can be controlled by a Top Stage Bold Line Temperature controller, by UNO or by the Okolab Stand Alone Temperature Controller. Okolab Objective Heater Features: Temperature controlled rubber band Easy to place around the ob…
The T Glass Plate - Round Transparent and flat surface at controlled temperature for Inverted Microscopes The T Glass Plate fits into the microscope XY stages with circular opening and provides a transparent and flat surface at controlled temperature. The combined action of the conductive glass with built in temperature sensor and of the state-of-the-art PID controller with 3.2’’ touch screen and advanced calibration routine e…
T Glass Table provides a transparent and flat surface at controlled temperature. It can be placed in the optical path of any stereo microscope to provide a large, flat, clear, warm surface where several specimens can be maintained at physiological temperature. The combined action of the conductive glass with built in temperature sensor and of the state-of-the-art PID controller with 3.2’’ touch screen and advanced calibration…
Metal T Plate is a one-button solution for temperature control. Ideal to warm up the specimen during experiments lasting from minutes to hours where humidity and CO2 control are not required. It fits into the microscope stages with 110x160 mm opening. The combined action of the metal plate with built in temperature sensor and of the state-of-the-art PID controller with 3.2’’ touch screen and advanced calibration routine ensure…
iCell® Cardiomyocytes, human induced pluripotent stem (iPS) cell-derived cardiomyocytes, aid drug discovery and improve the predictability of drug efficacy and toxicity screens, weeding out ineffective and potentially toxic compounds early in the pharmaceutical pipeline process before significant time and resources have been invested. iCell Cardiomyocytes are a mixture of spontaneously electrically active atrial, nodal, and ve…
iCell® Neurons, derived from human induced pluripotent stem (iPS) cells, provide a unique in vitro system for preclinical drug discovery, neurotoxicity testing, predictive disease modeling, and basic cellular research. A better and more biologically relevant alternative to current cell models, iCell Neurons offer researchers access to commercial quantities of high quality, highly pure human neurons that possess typical phenoty…
iCell® Hepatocytes, derived from human induced pluripotent stem (iPS) cells, provide access to commercial quantities of high quality, high purity human liver cells for preclinical drug discovery, hepatotoxicity testing, and disease research. iCell® Hepatocytes express alpha-1-antitrypsin (AAT), asialoglycoprotein receptor (ASGR1), hepatocyte nuclear factor 4 alpha (HNF4A), and secrete albumin at levels similar to adult primary…
iCell® Endothelial Cells, interior surface blood vessel cells derived from human induced pluripotent stem (iPS) cells facilitate vascular-targeted drug discovery, tissue regeneration, and other life science research. iCell® Endothelial Cells exhibit characteristic endothelial gene and protein expression (e.g., CD31, CD105, CD144, ZO-1, and von Willebrand Factor) and endothelial cell functions (e.g., tubular formation, acetylat…
MyCell® Products provide human induced pluripotent stem (iPS) cells and terminally differentiated cells manufactured from your donor samples to meet your specific needs. MyCell® Products include iPS cell reprogramming, genetic engineering, and cell differentiation. Choose the MyCell Products your research requires. MyCell® Products Benefits: “Footprint-free” iPS Cells - Reprogramming factors are introduced using non-inte…
The SIRTainty™ Class III HDAC Assay utilizes a novel patent pending technology for the sensitive detection of all known sirtuin family members. This easy to perform assay employs nicotinamidase to measure nicotinamide generated upon cleavage of NAD+ during sirtuin mediated deacetylation of a substrate providing a direct assessment of the activity of class III HDAC enzymes. Unlike conventional assays that are dependent upon a s…
The TL-1000-ASOPS timing stabilisation unit enables ultrafast time domain spectroscopy of rapidly changing systems by controlling an offset frequency between two Taccor GHz lasers. This allows scan rates of several kilohertz at a time-delay resolution of < 60fs, a performance that is impossible with conventional systems. Ultrafast time domain or pump probe spectroscopy is a technique with an expanding application range, where…
