Drug discovery > Basic Research Products & Reviews

The H-9500 is a high performance TEM featuring a single crystal LaB6 electron source. This allows 0.102 nm crystal lattice resolution and 0.18 nm point to point to be achieved. The instrument features a low magnification operating mode of x200 to x500 and a high magnification mode with zoom from x1000 to x1,500,000. Fully PC-controlled, the instrument has an icon-driven user interface and is designed for very fast operation. W…

The Optoscan monochromator from Cairn Research is the only instrument of its type to offer control of both centre-wavelength and bandwidth with millisecond time resolution. Combined with Cairn signal processing modules and optical hardware it forms the heart of a powerful and flexible microfluorescence system. Alternatively it can be readily integrated into commercial imaging systems, or custom controlled for bespoke applicati…

Thermo Scientific* Fermentas PCR Master Mix is a 2X concentrated solution of Taq DNA Polymerase, dNTPs and all the components required for PCR, except DNA template and primers. This pre-mixed formulation saves time and reduces contamination due to a reduced number of pipetting steps required for PCR set up. The mix is optimized for efficient and reproducible PCR. ■ Convenient—Taq DNA Polymerase in a ready-to-use mix ■ Fast—sa…

Versatile single and double beam spectrophotometers pre-programmed with food and beverage analyses.

Product Type: antibody. Immunogen: native, from brain. Host: mouse. Type: monoclonal. Clone: 31A3. Subclass: IgG1. Format: affinity purified Ig. Preparation: prepared by Protein A chromatography. State: liquid. Buffer: PBS buffer, pH 7.2, 0.1% Sodium Azide. Storage: aliquot and store at -20°C.Cross reactivity Reacts with PGP 9.5 from human and rat. Tissue reactivity Stains neuronal cell bodies and axons in the CNS and peripher…

Product Type: antibody. Immunogen: native, from plasma. Host: mouse. Type: monoclonal. Clone: 10-11. Subclass: IgG1-k. Format: affinity purified Ig. Preparation: Protein A chromatography. State: liquid. Buffer: borate buffered saline, pH 8.4, 0.1% sodium azide. Storage: aliquot and store at -20°C.Cross reactivityDoes not react with C4c. Does not cross react with cow, cat, dog, guinea pig, mouse, rabbit, sheep or rat.Specificit…

Product Type: antibody. Immunogen: native. Host: goat. Type: polyclonal. Format: purified Ig. Preparation: Ammonium Sulphate fractionation. State: liquid. Buffer: PBS buffer, pH 7.2, 0.1% Sodium Azide. Storage: aliquot and store at -20°C.ImmunohistochemistryThis antibody, when tested in the serum format, has given variable results in IHC. The purified product has not been evaluated for this application by Biogenesis.ELISAIn a…

Product Type: antibody. Immunogen: native, purified. Host: sheep. Type: polyclonal. Format: serum. Preparation: neat. State: liquid. Buffer: without preservatives. Storage: aliquot and store at -20°C.RIA 1/4K - 1/20K (125 I) IHC to be determined Cross reactivity rat GH 100% rat ACTH Suggested protocol Overnight (16-24 hr) equilibrium assay with DAB/PEG separation. 100 µl standards, 100 µl tracer (18,000 cpm) and 200 µl primary…

Product Type: antibody. Immunogen: native. Host: mouse. Type: monoclonal. Clone: 5B6/6. Subclass: IgG1-k. Format: affinity purified Ig. Preparation: Protein A chromatography. State: liquid. Buffer: PBS buffer, pH 7.4, 0.1% Sodium Azide. Storage: aliquot and store at -20°C.Cross reactivityReacts with human, porcine, bovine, rat and mouse insulin and proinsulin.SpecificityEpitope recognised is different from that identified by 5…

Product Type: antibody. Immunogen: BSA conjugate. Host: mouse. Type: monoclonal. Clone: V/h1. Subclass: IgG1. Format: affinity purified Ig. Preparation: Protein A chromatography. State: liquid. Buffer: PBS buffer, pH 7.2, 0.1% Sodium Azide. Storage: aliquot and store at -20°C.RIA titre to be determined ELISA titre to be determined IHC titre to be determinedCross-reactivityReacts with pure MBP from sheep, rabbit, guinea-pig and…

Product Type: antibody. Immunogen: native, see notes. Host: mouse. Type: monoclonal. Clone: AE5. Subclass: IgG1. Format: affinity purified Ig. Preparation: Ion Exchange chromatography. State: liquid. Buffer: PBS buffer, pH 7.2, 0.1% Sodium Azide. Storage: aliquot and store at -20°C.Cross reactivityReacts with bovine and rabbit snout and lip epithelium. Reacts with some oral mucosa epithelium. This antibody also reacts with rab…

Product Type: antibody. Immunogen: native, from umbilical cord. Host: sheep. Type: polyclonal. Format: affinity purified Ig. Preparation: prepared by Protein G chromatography. State: liquid. Buffer: PBS buffer, pH 7.2, 0.1% Sodium Azide. Storage: aliquot and store at -20°C.ELISA 1/50 - 1/400

Product Type: antibody. Immunogen: native, from placenta. Host: rabbit. Type: polyclonal. Format: affinity isolated. Preparation: affinity chromatography. State: lyophilised. Buffer: contains mannitol, dextran and salts. Storage: store at -20ºC, aliquot reconstituted at -20ºC.Cross reactivityHuman collagen type III SpecificityThis antibody reacts with native and heat denatured collagen type I. Human plasma proteins do not inte…

The program "Genom 2005" is a feature rich and user friendly tool to analyse array-experiments.Key Features:Analyse all AffyMetrix-Arrays (cDNA-Arrays or similar technologies could easily be integrated as well) Normalisation of Raw-Data Many additional gene information (official Gennames, Location, Function prediction, Sequences, Database-references (Gene-Ontology, InterPro, SwissPROT ,EMBL, ENSEMBL, LocusLink, OMIM, GeneBank.…

ramé-hart instrument co. is pleased to offer our Model 100. Based on the classic design of Dr. William Zisman and with over 40 years of experience, this tool is proven for its accuracy and ease of use. Many modular options are available -- including an imaging upgrade kit with camera and software -- and allow the user to make sophisticated measurements.This model provides the surface scientist or technician with the tools nece…

Kit for the isolation of genomic DNA from mammalian whole blood, blood cells, or cultured cells using the MagNA Pure LC Instrument.For general laboratory use. The MagNA Pure LC DNA Isolation Kit I is designed to isolate high-purity genomic DNA from mammalian whole blood, blood cells, or cultured cells using the MagNA Pure LC Instrument. The purified DNA can be used directly in PCR on the LightCycler® Carousel-Based Systems, th…

Kit for the isolation of DNA from mammalian tissues using the MagNA Pure LC Instrument.For general laboratory use. The MagNA Pure LC DNA Isolation Kit II (Tissue) is designed to isolate high-purity DNA from mammalian tissues using the MagNA Pure LC Instrument. The purified DNA can be used directly in PCR on the LightCycler® Carousel-Based Systems, the LightCycler® 480 System, or standard thermal block cyclers. Benefits…

Kit for the isolation of genomic DNA from up to 1 ml of mammalian whole blood, blood cells, or cultured cells using the MagNA Pure LC Instrument.For general laboratory use. The MagNA Pure LC DNA Isolation Kit – Large Volume is designed to isolate high-purity genomic DNA from mammalian whole blood, blood cells, or cultured cells using the MagNA Pure LC Instrument. The purified DNA can be used directly in PCR on the LightCycler®…

For general laboratory use. The MagNA Pure LC DNA Isolation Kit Lysis/Binding Buffer Refill is designed to lyse mammalian blood, blood cells, or cultured cells, and stabilize nucleic acids. After the addition of Lysis/Binding Buffer to the sample, the cells are lysed and enzymes (e.g., ribonucleases) are effectively inactivated. The lysed and stabilized samples can be immediately processed (or after long-term storage) with the…

Kit for the isolation of total nucleic acid from mammalian serum, plasma, and whole blood using the MagNA Pure LC Instrument For general laboratory use. The MagNA Pure LC Total Nucleic Acid Isolation Kit is designed to isolate high-purity total nucleic acid (e.g., viral DNA and RNA) from mammalian serum, plasma, or whole blood using the MagNA Pure LC Instrument. The purified nucleic acid can be used directly in PCR on the Ligh…

Kit for the isolation of total nucleic acid from up to 1 ml of mammalian serum or plasma using the MagNA Pure LC Instrument For general laboratory use. The MagNA Pure LC Total Nucleic Acid Isolation Kit - Large Volume is specifically designed to purify total nucleic acid (e.g., viral DNA and RNA) from large amounts (up to 1 ml) of serum and plasma using the MagNA Pure LC Instrument. The purified total nucleic acid can be used…

For general laboratory use. The MagNA Pure LC Total Nucleic Acid Isolation Kit – Lysis/Binding Buffer Refill is designed for lysis of mammalian blood, serum, or plasma samples, and the stabilization of nucleic acids. After the addition of Lysis/Binding Buffer to the sample, the cells are lysed and enzymes (e.g., ribonucleases) are effectively inactivated. The lysed and stabilized samples can be immediately processed (or aft…

Kit for the isolation of total RNA from mammalian whole blood, blood cells, and cultured cells using the MagNA Pure LC Instrument For general laboratory use. The MagNA Pure LC RNA Isolation Kit - High Performance is designed to isolate high-purity total RNA from mammalian whole blood, blood cells, or cultured cells using the MagNA Pure LC Instrument. The purified RNA can be used directly in RT-PCR on the LightCycler® Carousel-…

Kit for the isolation of total RNA from mammalian tissue using the MagNA Pure LC Instrument For general laboratory use. The MagNA Pure LC RNA Isolation Kit III (Tissue) is designed to isolate high-purity total RNA from flash-frozen or formalin-fixed, paraffin-embedded mammalian tissue samples using the MagNA Pure LC Instrument. Unfrozen tissue stabilized by specific reagents (like RNAlater) can also be used. The RNA purified f…

For use with:Cat. No. 03 172 627 001 MagNA Pure LC mRNA Isolation Kit II (Tissue) orCat. No. 03 330 591 001 MagNA Pure LC RNA Isolation Kit III (Tissue) For general laboratory use. The MagNA Pure LC RNA Isolation Tissue Lysis Buffer – Refill is designed for lysis and homogenization of fresh frozen tissue samples using a tissue homogenizer (see the MagNA Lyser Instrument) stabilization of total RNA and mRNA within samp…