Drug discovery > Basic Research Products & Reviews

For labs that require high throughput and automated RNA in situ hybridization (ISH) analysis, ACD has partnered with Leica Biosystems and Roche Tissue Diagnostics to deliver RNAscope ISH automated assays.

The BaseScope™ Assay is a unique product from ACD, based on the same platform of proven and established RNAscope™ technology that has been cited in over 2300 publications. This powerful assay provides new data dimensions and unique insight into biological mechanisms. The BaseScope™ Assay enables applications such as the detection of exon junctions/splice variants, short/highly homologous RNA sequences (50-300 bases), and poin…

The RNAscope™ and BaseScope™ Assays are based on the proprietary RNAscope Technology enabling RNA target expression analysis within intact cells and tissues with high sensitivity and specificity. Using proprietary ACD RNAscope Probe Design Pipeline, we provide double "Z" oligo probes designed to hybridize to your specific RNA target of interest.

Introducing RNAscope HiPlex assay to expand your in situ hybridization potential.

Guaranteed editing with predesigned gRNA designs

Use our proprietary algorithms to design custom Cas9 guide RNAs

Guide RNAs (gRNAs) contain the target-specific sequence for guiding Cas9 protein to a genomic location.

Guide RNAs (gRNAs) contain the target-specific sequence for guiding Cas9 protein to a genomic location.

Guide RNAs (gRNAs) contain the target-specific sequence for guiding Cas9 protein to a genomic location.

Hybridizes to crRNA to activate the Cas9 enzyme.

Hybridizes to crRNA to activate the Cas9 enzyme.

urified carrier DNA that improves delivery of Cas9 ribonucleoprotein (RNP) by electroporation.

crRNAs contain the target-specific sequence for guiding Cas12a protein to a genomic location.

crRNAs contain the target-specific sequence for guiding Cas12a protein to a genomic location.

Guide RNAs for novel Cas enzymes (e.g., prime editing or the Cas13 family)

Purified carrier DNA that is required for efficient delivery of Cpf1 ribonucleoprotein (RNP) by electroporation.

Built for homology-directed repair (HDR)

For detection of on-target or known off-target CRISPR events in cultured cells

An advanced data analysis pipeline for quantifying your genome editing results

Highly multiplexed, targeted amplicon sequencing for critical analysis of your CRISPR edits

NGS-ready amplicon libraries. Fast. Easy. Convenient.

A small molecule compound that has demonstrated an ability to increase the rate of homology-directed repair (HDR).

Deep, targeted amplicon sequencing with highly multiplexed panels for sequencing on Illumina platforms.

DsiRNAs are 27mer duplex RNAs that demonstrate increased potency in RNA interference compared to traditional, 21mer siRNAs. Proprietary design rules produce optimized DsiRNAs that are available only from IDT.

Antisense oligonucleotides (ASOs) are short oligonucleotides that localize to the nucleus and provide a pathway for gene silencing by the RNase H pathway. Phosphorothioate (PS) linkages are available to confer nuclease resistance and, therefore, enhance intracellular stability.