Drug discovery > Basic Research Products & Reviews

Optimized cryopreservation – versatile and ergonomic   

CN Bio supports non-alcoholic steatohepatitis (NASH) therapeutic development via fast-track NASH Contract Research Services. NASH Services enable you to gain instant access to CN Bio’s expertise and one of the most advanced human in vitro models available. Submit lead candidates for screening and receive human translatable data for insightful preclinical candidate prioritization, clinical trial design and optimization.

Multi-chip Liver-12 consumable plates from CN Bio enable the advanced culture of 12 human 3D liver microtissues under perfusion/plate. Each microtissue recapitulates the functionality and microarchitecture of the human liver to accurately predict drug responses.

Multi-chip Barrier (MPS-T12) consumable Plates from CN Bio are used to culture advanced in vitro barrier models under perfusion, such as gut-on-a-chip or lung-on-a-chip, to predict human drug responses more accurately.

CN Bio supports R&D efforts via fast-track Drug Metabolism and Safety Toxicity Testing Services that deliver human translatable insights from lead candidates in a few weeks and at lower cost than animal studies. By accessing the Company’s expertise and advanced in vitro liver-on-chip models, these Services enable researchers to step beyond standard in-house laboratory workflows for better informed pre-clinical decisions.

Multi-chip Dual-organ (MPS-TL6) consumable plates from CN Bio are used to culture interconnected 3D in vitro multi-organ-on-chip models under perfusion, such as Gut/Liver, or Lung/Liver, to generate clinically translatable data.

Dried blood spot specimen stability makes it a practical alternative to venous blood. Instead of traveling to a clinic to get blood drawn, a blood spot sample can be taken at a convenient site and mailed to a laboratory. It opens new possibilities in testing, such as comparison of historical to current patient results; simplified blood sampling for patients in remote locations, for those who are homebound or those that pre…

Dried blood spot specimen stability makes it a practical alternative to venous blood. Instead of traveling to a clinic to get blood drawn, a blood spot sample can be taken at a convenient site and mailed to a laboratory. It opens new possibilities in testing, such as comparison of historical to current patient results; simplified blood sampling for patients in remote locations, for those who are homebound or those that prefer…

Dried blood spot specimen stability makes it a practical alternative to venous blood. Instead of traveling to a clinic to get blood drawn, a blood spot sample can be taken at a convenient site and mailed to a laboratory. It opens new possibilities in testing, such as comparison of historical to current patient results; simplified blood sampling for patients in remote locations, for those who are homebound or those that pre…

Glicentin is a 69 amino acid N-terminal peptide derived from proglucagon (PG 1-69) by posttranslational processing in the intestine by intestinal L-cells. Glicentin can further be processed into oxyntomodulin, corresponding to proglucagon residues no 33-69. These peptides are released simultaneously upon stimulation. Glicentin is a pro-glucagon derived gut peptide that is released in the gut in response to feed intake. It is…

Fast-track your route to successful NASH therapeutic development with CN Bio's 3D NASH model.

Multi-chip Liver-48 consumable plates from CN Bio enable the advanced culture of 48 miniaturized in vitro 3D liver microtissues under perfusion/ plate for comparative drug screens. Each microtissue recapitulates the functionality and microarchitecture of the human liver to accurately predict drug responses.

Maximum purity for optimal safety in preanalytics

The iLite® Functional Bioassay portfolio consists of cell lines provided in an “assay-ready” format for a rapid and convenient workflow. The assay-ready format also reduces assay variability, optimizing its use in screening, characterization, stability, and potency studies. iLite cell lines can be tailored to virtually any biopharmaceutical target.

The iLite® Fc Effector Reporter Gene Bioassays Portfolio offers a variety of reporter gene cell lines and target cells that can be used in MOA-reflective assays to measure the Fc effect of antibodies and other biologics that specifically bind and activate Fc receptors. Using a Luciferase reporter gene system offers a convenient and powerful way of measuring antibodies' in vitro efficacy in triggering ADCC and ADCP.

In diagnosis of Rheumatoid Arthritis (RA), the measurement of anti-CCP is integral. People who test positive for Anti-CCP, are very likely to develop or have already developed RA, but not all who have RA, necessarily develop anti-CCP. Early detection of RA is crucial for reducing tissue damage.

A biologically relevant and powerful way to assess CD32/FcyRlla induced effects.

Engineered, homologous, and specific target cells that enable screening for antibody-induced effector functions.

The iLite® CD3 Effector Cell line is a reporter gene cell line that offers a convenient and powerful way of measuring the efficacy antibodies have to elicit  T cell activation through CD3  interactions.

Svar CRO Services provides direct value through an extensive toolbox of in-house products, scientific expertise, and end-to-end customizable solutions – everything to ensure the success of your drug development program.​

Expert Biomarker Discovery Services using cutting-edge technologies such as high-quality proteomics with Proximity Extension Assay (PEA) technology from Olink, and ultra-sensitive detection with proven Simoa technology. We offer ideal broad screening-to-targeted biomarker discovery solutions in different therapeutic areas.

A specialized and GxP-certified laboratory for Bioanalytical Service Solutions -with scientific expertise & advanced technologies. We offer assay development, validation, and sample analysis of pharmacokinetics, toxicokinetic, pharmacodynamics, immunogenicity, and biomarker analysis.

The Temperature-Validation System for the entire Mastercycler family enables simple and rapid validation and calibration of the temperature on the universal blocks of the cyclers. The program for automatic measurement and calibration is integrated into the Mastercycler software, thus furnishing the Mastercycler family with an accurate and precise system that meets all documentation and detection requirements in the laboratory.

The Eppendorf CycleManager is a Windows based software for programming and controlling one or more Mastercyclers. The thourough databank ensures reliable storage of all GLP relevant experimental data incl. detailed user comments.The main dialogue box is the central user interface. All key functions can be accessed from it. Mastercyclers can be added or removed from the Multi-Cycler-Network. It offers also an overview of all co…

• Strips with 8 microcaps for 0.2 ml wells• Easy and rapid sealing of Eppendorf twin.tec plates and other standard microtiter plates, see also Capping Aid• Easy to remove using extension at the end of the strip• Autoclavable (121°C, 20 min.)• Certified free of human DNA, DNase, RNase and PCR Inhibitor**Certificate, test procedures and detailed information on request.