ZE5 Cell Analyzer
The ZE5 Cell Analyzer is the only flow cytometer with the ideal combination of production throughput, smart sample-handling and superior speed and sensitivity to meet your research needs.
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Flexible, high-throughput, versatile, but pricey setup.
Cell analysis
Highly effective for complex, high-throughput analysis.
Review Date: 27 Oct 2025 | Bio-Rad
ZE5 Cell Analyzer accessible for novice flow cytometry users yet flexible.
Biotechnology
The ZE5 Cell Analyzer is an innovative flow cytometer with flexible configurations to meet a broad range of experimental complexities and throughput needs. Low sample carryover with built-in auto probe wash. Innovative sample pump that takes up samples with minimal dead volume and returns unused sample multi-parameter analysis. The Everest application program interface and software development kit allow the to interface with existing automation systems. It is user friendly.
Review Date: 18 May 2021 | Bio-Rad
High powered flow that allows expansion and growth.
Analysis of cells
Bio-Rad's ZE5 is a machine that might not be used to its full capacity initially, but having the ability to grow, add stains, add cell types, add colors, etc. makes it worth its weight. We've added multiple panels since purchasing this machine. The software is fairly intuitive and easy to use making it easy to train new users.
Review Date: 2 Jul 2020 | Bio-Rad
Excellent product! I recomend.
Toxicology experiments, academic purpose
Features rare cells, up to 100,000 events per second. Study populations and small particles with ease, Expand your panels with up to 27 bright colors.
Review Date: 18 Feb 2019 | Bio-Rad
The ZE5 Cell Analyzer is the only flow cytometer with the ideal combination of production throughput, smart sample-handling and superior speed and sensitivity to meet your research needs.
High-throughput Production
- Detect up to 100,000 events per second without compromising data quality
- Low sample carryover with built-in auto probe wash
- Integrated 96/384/deep-well plate sample loader
Smart Sample-handling
- Temperature control and vortexing to maintain cell viability and prevent clogging
- Innovative sample pump that takes up samples with minimal dead volume and returns unused sample
Multi-Parameter Analysis
- Up to five lasers and 30 detectors including seven colors off UV for building larger panels, or panels with minimal compensation
- Small particle detector in 3-5 laser configuration for studying exosomes and other small particles
Automation/Robotics-friendly
- API to connect to LIMS and scheduling software for integration to existing or new workcells
Flow cytometry–based exosome detection and analysis using the ZE5 Cell Analyzer
In this application note, surface exosome marker proteins such as CD63 and CD81, as well as intravesicular markers ALIX and TSG101, are detected using the ZE5 Cell Analyzer. Explore how the ZE5’s unique features allow it to be used in small particle analysis in addition to studying large cancer cells.
Automation of high-throughput flow cytometry with the ZE5 Cell Analyzer
In this application note, Bio-Rad demonstrates how the integration of the ZE5 Cell Analyzer and Biosero's Green Button Go Automation Scheduling Software delivers automated, high-throughput flow cytometry.
ZE5 Cell Analyzer
In this application note, Bio-Rad introduces the ZE5 Cell Analyzer, designed for speed, automation, and flexibility to allow you to choose the right conditions for analyzing your cells.
A 19-color multiparameter white blood cell panel designed for the immunophenotyping of normal and malignant leukocytes by flow cytometry
With the advent of flow cytometry into the clinical arena as a diagnostic tool, high-dimensional multicolor analysis has become increasingly recognized as invaluable for the diagnosis and classification of leukemia. In this application note, a 19-antibody white blood cell panel was developed using the ZE5 Cell Analyzer from Bio-Rad Laboratories.
Utilizing the multiparameter capability of the ZE5 cell analyzer to monitor T cell exhaustion and effects of immunotherapy
T cell exhaustion is a hyporesponsive state of T cells characterized by sustained expression of suppressive cell surface markers, decreased effector cytokines, and impaired cytotoxicity. In this application note, Bio-Rad monitor in-depth changes to the T cell phenotype, exhaustion, and cellular subset identity markers using a 16-parameter panel developed for use with a 5-laser ZE5 Cell Analyzer.
A fast and flexible screening flow cytometer
In this video, hear how flow cytometry has evolved to be amenable to high-throughput screening in drug discovery. Discover how the ZE5 Cell Analyzer from Bio-Rad combines the speed of a screening instrument with high-parameter data acquisition, giving it the flexibility to deal with the simplest or the most complex screening applications, faster than ever.
COVID-19: Meet the scientist making significant advances to better understand our immune system
Leading scientist reveals more about her groundbreaking research exploring T cells that target SARS-CoV-2, which has inspired scientists from across the world to understand how T cells, rather than antibodies, drive immunity to the virus
Accelerated production of novel immunotherapies with high-throughput screening
Dr. Dallas Flies, Vice President, Discovery Research, NextCure, Inc. discusses the cutting-edge technology transforming the identification of new targets for the development of effective immunotherapeutics
Bio-Rad introduces three StarBright Dyes for flow cytometry
The StarBright Violet 570, StarBright Violet 670, and StarBright Violet 710 Dyes offer precise excitation and emission spectra for improved brightness and resolution
Bio-Rad introduces StarBright Violet 515 Dye for flow cytometry
New dye offers researchers improved brightness to resolve rare and low antigen density populations more easily
Bio-Rad to Unveil New Solutions for Streamlined Long Noncoding RNA (lncRNA) Research at AACR 2019
Innovative workflow promises highly sensitive detection of lncRNAs by qPCR and ddPCR to help researchers “overcome challenges associated with lncRNA expression analysis”
Spotted at SLAS2019: 9 Top Technologies from the Exhibition Floor
SelectScience editors reflect on the most exciting technologies showcased at the 2019 Society for Laboratory Automation and Screening conference
Product Overview
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Products Model Information
ZE5 Cell Analyzer 3 laser (488/561/640 nm)
Bio-RadZE5 Cell Analyzer; flow cytometer with 488 nm, 561 nm, and 640 nm lasers, 17 fluorescence detectors, plus SSC, FSC; Everest software, flexible sample loader, ZE5 EYE, integrated fluidics
ZE5 Cell Analyzer 3 lasers (405/488/640 nm)
Bio-RadZE5 Cell Analyzer, flow cytometer with 405 nm, 488 nm, and 640 nm lasers, 17 fluorescence detectors, plus SSC, FSC, Everest software, flexible sample loader, ZE5 EYE, integrated fluidics
ZE5 Cell Analyzer 4 laser (405/488/561/640 nm)
Bio-RadZE5 Cell Analyzer; flow cytometer with 405 nm, 488 nm, 561 nm, and 640 nm lasers, 24 fluorescence detectors, plus SSC, FSC, Everest software, flexible sample loader, ZE5 EYE, integrated fluidics
ZE5 Cell Analyzer 5 laser (355/405/488/561/640 nm)
Bio-RadZE5 Cell Analyzer; flow cytometer with 355 nm, 405 nm, 488 nm, 561 nm, and 640 nm lasers, 27 fluorescence detectors, plus SSC, dual FSC, Everest software, flexible sample loader, ZE5 EYE, integrated fluidics
