X-CLARITY™ Tissue Clearing System
The X-CLARITY™ Tissue Clearing System is essential for non-destructive, 3D imaging of biological samples. The X-CLARITY™ Tissue Clearing System II is an all-in-one, easy-to-use solution for electrophoretic tissue clearing. It's unique design accelerates the removal of lipids from tissues while preserving the structural integrity of the sample.
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Excellent.
Biopharmaceuticals
We are very happy with the product and it is very reliable and safe.
Review Date: 16 Jan 2020 | Logos Biosystems
Results were great!
Mouse and rat brain
I have used this machine for tissue clearance transparent experiments, results was good
Review Date: 19 Jun 2019 | Logos Biosystems
Always use this, cannot complain!
Analyzing tissue systems
This was an excellent product that I would highly recommend for colleagues. It was easy to use and it shipped very quickly. Our group has previously used this product and will continue to do so.
Review Date: 19 Jun 2019 | Logos Biosystems
Great product, produces rich data.
Clearing of whole brain samples to study astrocyte plasticity
So far, clarity has helped us to get amazing data on astrocyte morphology in the olfactory bulb. Thanks to the clearing, it makes slicing the tissue for microscopy redundant. Therefore we are able to study the more complex networks in their physiological form. Great product!
Review Date: 20 Mar 2019 | Logos Biosystems
It really facilitated the tests I performed during my PhD.
Neural tissue clarification
X Clarity system is a very easy-to-use and versatile instruments. I started using it for murine brains, and it was quite easy to customize the protocols also for different biological samples (e.g., 3D advanced neural constructs). It allows me to avoid both waste of time and money.
Review Date: 15 Feb 2019 | Logos Biosystems
A definitive solution for both experts and dummies
Samples preparation for deep tissues imaging in microscopy facility
X-Clarity is the definitive solution for an effective, robust and highly repeatable clearing. X-Clarity helps cleraring expert users to have more reproducible and standardized data, opening the possibility to have robust quantitative data even from cleared tissue samples, as well as dummies that look out this technique for the first time. In our facility very often people who had never even been done just simple immunofluorescences they were able to get perfect cleared samples for imaging (confocal or two-photon) We are now interested in improving deep label capabilities and logos is very in proposing their solutions.
Review Date: 3 Sept 2018 | Logos Biosystems
It is an essential material for our research.
tissue clearing
Very easy to use. It gives robust and reproducible results and allows us to standardize the methodological chain.
Review Date: 3 Sept 2018 | Logos Biosystems
Great results, easy to use!
Analyze full brain tissue
This product was effective at clearing my tissue samples. It cleared whole brains, hearts, stomach, kidneys, livers, etc. The user manual was easy to read and easy to follow. There is little attention and maintenance required while the system in running.
Review Date: 9 Aug 2018 | Logos Biosystems
Great instrument and would highly recommend
Used to clear nervous system tissues
This tissue clearing system is very easy to use and is very user friendly. I've used it to clear mouse nerves and spinal cords in approximately 4-6 hours. When the system first arrived, there was an issue with the ETC controller, but customer service handled it very efficiently and quickly. We've been getting great results with this system and I would highly recommend it to anyone interested in tissue clearing.
Review Date: 9 Aug 2018 | Logos Biosystems
Confident system and confident company.
ischemia reperfusion syndrome
I work on the X-clarity system every days and i can says that there is a very reliable system. The simpler utilization and the ergonomic of the machine is appreciable. The customer service can not be more efficient, any problem are resolved in the day or two day maximum and the communication is based on mutual confidence. I recommend Logos society and X-clarity system.
Review Date: 25 Jul 2018 | Logos Biosystems
The X-CLARITY™ Tissue Clearing System is an all-in-one, easy-to-use solution for electrophoretic tissue clearing. Its unique design accelerates the removal of lipids from tissues while preserving the structural integrity of the sample. The X-CLARITY™ Tissue Clearing System can clear a whole mouse brain in just 6 hours, an astounding 8 times faster than the original technology.
Complicated wires are combined into a single cable for power supply and control. Improved electrodes generate a uniform electric field that eliminates uneven voltages and currents. A timer allows precise control over the clearing time by automatically turning off the current at the end of the allotted time. An active cooling system minimizes the probability of artifacts arising due to poor temperature control. Buffer circulation ensures consistent buffering capacity, temperature control, and elimination of electrophoretic byproducts. This advanced system ensures that tissue clearing occurs efficiently and rapidly. Moreover, the X-CLARITY™ Tissue Clearing System successfully produces transparent tissues that are efficiently penetrated by and labeled with macromolecules such as antibodies or oligonucleotides. This allows for the 3D imaging of large tissues at single-cell resolution.
Key Features:
- Exceptional transparency
- Rapid clearing
- Simple setup and operation
- Pre-optimized protocols
- Efficient antibody labeling
Brochures
X-CLARITY - Systems and Reagents for Tissue Cleaning
Tissue clearing has become an important step for imaging tissues in 3D at single-cell resolution
An Automated and High-Throughput Polymerization Solution for Downstream Tissue Clearing
The tissue clearing method CLARITY transforms intact tissue into tissue-hydrogel hybrids from which lipids are removed to make structurally stable and optically transparent tissues. A key step of the CLARITY method is creating the tissue-hydrogel hybrid to physically support the tissue ultrastructure and preserve molecular information during the lipid clearing process.
Improving Antibody Penetration in Tissues
This poster illustrates the use of X-CLARITY and DeepLabel antibody staining kit in combination, to acquire high-resolution volumetric images of diverse organ tissue.
Time Lapse Video of a Mouse Brain Being Cleared
Watch the X-CLARITY™ in action, and learn how it can accelerate your research.
3D Imaging with the X-CLARITY™ Tissue Clearing System
Journey through the brain with the X-CLARITY™ Tissue Clearing System.
How to achieve high-quality imaging of neurological tissues
Learn how one scientist is harnessing the latest imaging technology to advance his research and generate high-resolution images of neural tissue
