Vivaflow®
Vivaflow® is the original plug-and-play tangential flow filtration (TFF) solution for handling samples up to 5 L in research and development laboratories.
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Essential to workflow. Reliable and consistent.
protein purification
I have used a lot of spin concentrators over the past 30 years and Vivaspin are the only ones I trust. Always work well, no leaks, consistent performance and excellent sample recovery.
Review Date: 15 Jul 2022 | Sartorius Group
Vivaflow® is the original plug-and-play tangential flow filtration (TFF) solution for handling samples up to 5 L in research and development laboratories.
For feed volumes of 100 mL and more, concentration and buffer exchange using centrifugal ultrafilters is cumbersome, labor intensive and time consuming, leading to a decrease in productivity. However, TFF based on scale-down process technology is expensive, complicated and requires additional effort in process optimization.
A trusted partner in separation workflows for a quarter of a century, Vivaflow® features an all-in-one design with a unique switchback flow path that enables fast, low effort ultrafiltration and diafiltration using a standard pump. A choice of two membrane areas in multiple MWCOs suits many common sample types. The cassettes are also suitable for multiple runs without the need to replace the membranes, supporting greater process economy.
Supplied complete with a tubing kit, each cassette can be set up and run individually in ultrafiltration mode right out of the box. In addition, an enhanced selection of predefined tubing kits is available when tubing replacement, diafiltration, or running two cassettes in parallel is required.
If you are interested in a single-use option, Sartorius also offers Vivaflow® SU, which makes lab-scale TFF even more intuitive, effortless and sustainable.
Brochures
Sustainability facts sheet of Vivaflow SU
Vivaflow® SU is an official nominee in the Scientists' Choice Awards for Sustainable Lab Product of the Year.
Enhance your ultra and diafiltration capabilities using a sustainably made next-generation tangential flow filtration (TFF) cassette. Discover how the Vivaflow® SU delivers faster process speeds and higher recoveries for virtually any molecule, without the need for expensive equipment or complicated process optimization. Plus, learn how Sartorius has placed sustainability at the fore-front using local sourcing and logistical strategies.
Advancing sustainability with eco-friendly lab products for tomorrow's science
Sartorius aims to champion sustainability in terms of environmental, social, and corporate governance aspects, implementing sustainable practices in its operations, and carefully choosing partners who share its sustainability values. Explore how, through ongoing research into materials and design, Sartorius strives to reduce its environmental footprint and enhance product recyclability. Discover how Sartorius laboratory solutions are designed with the entire product life cycle in mind, from pre-manufacturing to disposal, to minimize environmental impact.
Concentration and purification of viruses by using ultrafiltration, incl. Coronavirus – a short review
This short review from Sartorius highlights the concentration and purification steps of various viruses in the context of different research applications. The discussed methods find application in medical research, marine biology as well as in research concerning drinking water and food quality. You will find a guidance for the selection of an ideal performing ultrafiltration device with the optimum molecular weight cut-off (MWCO) for typical concentration applications.
COVID-19 vaccine research challenges and solutions
Accounting for at least 15% of all human pathogens, emerging infectious diseases (EID) pose a significant burden on public health. Vaccination represents one of the most successful prophylactic tools for disease prevention and control, however, the development process is typically lengthy and expensive. While there has been a rapid development of multiple safe and highly effective vaccines in response to the current COVID-19 pandemic, there are still many challenges to overcome. This application note will explore the common challenges of vaccine development and the solutions available to overcome them.
An improved method to wash graphene prior to use as a drug delivery vehicle
Graphene is suitable for use in many biomedical applications, including gene and drug delivery. In this application note, Sartorius compares three methods of washing to neutralize graphene oxide—centrifugation with short and long steps, and TFF using Vivaflow®.
Sartorius ultrafiltration products in the preparation of biological nanoparticles and medical nanocarriers
In this application note, Sartorius outlines ultrafiltration of various biological nanoparticles and medical nanocarriers, and provides guidance on selecting the right ultrafiltration device for your lab. The nanomaterials discussed comprise metals, polymers, lipids (in vesicles and micelles) and proteins.
Efficient sampling procedures for SARS-CoV-2 in air and wastewater
The novel coronavirus (SARS-CoV-2) outbreak has created an urgent need to develop and optimize methods to sample the virus both in aerosols, its primary transmission route, as well as in wastewater, a surveillance method to track and manage infections. As such, reliable air and water monitoring protocols are crucial in accurately detecting COVID-19 and managing the dynamics of the pandemic.
In this free eBook, we provide a compendium of methods to collect viruses from air and water samples, concentrate viral proteins, and optimize sample preparation for PCR-based COVID-19 detection. Download now to explore content including:
- Sampling airborne viruses
- Gelatin membranes for air sampling
- Coronavirus detection from aerosols
- Ultrafiltration of water samples
- Sample preparation toolkit
Lab ultrafiltration tips and tricks
The use of ultrafiltration membranes for concentration and purificationof proteins and DNA is ubiquitous in biological laboratories. Filter devices with ultrafiltration membranes can also be used for concentration of other macromolecules such as inorganic polymers, nanoparticles or even viruses. Although performing sample concentration and buffer exchange using an ultrafiltration device is relatively simple, some tricks of the trade can improve your recovery or speed up your work flow considerably.
Ultimate Cell Culture Workflow Compendium
This application compendium pulls together everything you need to ensure successful cell culture in your lab, including a range of compatible products and guides on how to use them most effectively. The downloadable eBook presents top expert tips to ensure consistency and reproducibility in your results and highlights examples of effective cell culture preparation steps, experimental protocols, and subsequent analysis.
Tips for sustainably optimizing your nanoparticle preparation workflows
Learn how nanoparticles are transforming drug delivery in healthcare, and how ultrafiltration technology is being used for analysis and optimization of nanoparticle workflows
