TSKgel SuperQ-5PW Anion Exchange Media by Tosoh Bioscience

The TSKgel SuperQ-5PW resin is a strong anion exchange resin for biomolecule purification which is especially suited to purify oligos from longmers and shortmers. It is composed of highly crosslinked polymethacrylate beads that have been functionalized with quaternary amine (Q) strong anion exchange groups. TSKgel SuperQ-5PW is available in two particle sizes: 30 µm and 20 µm.

TSKgel SuperQ-5PW resins are best used for high resolution process polishing steps and for the purification of therapeutic oligonucleotides from synthesis impurities. It is applied in industrial manufacturing processes of approved siRNA therapeutics. 

TSKgel Super-Q Features: 

• High binding capacity for nucleic acids and proteins
• Efficient N-X and N+1 impurity removal at high oligo loadings
• High mechanical and chemical stability