Member since: 2020
Organization: West Virginia University
Ideal for separating large molecules from mAbs.
Application Area: Liquid chromatography
"Ideal for separating large molecules from mAbs. Did not separate dye well."
MAbPac™ SEC– 1 for Monoclonal Antibody (MAb) Analysis
MAbPac™ SEC-1 is a size exclusion chromatography (SEC) column designed for monoclonal antibody (MAb) analysis, including monomers, aggregates, and fragments, under non-denaturing conditions, and in both high- and low-salt mobile phases and volatile eluents.
SEC is frequently used because of its simple operating principle and features not found in other separation techniques including separating aggregates that are not easily distinguished by other chromatographic means. MAbs produced from mammalian cell culture may contain significant amounts of dimers and higher-order aggregates. The MAbPac SEC-10 is a high-resolution SEC column that is suitable for use with a wide range of biomolecules, including monoclonal antibodies and their aggregates.
MAbPac™ SEC-1 Monoclonal Antibody Analysis Column Features: