Thermo Scientific™ Pharma11 Twin-screw Extruder
The Thermo Scientific Pharma 11 is a unique, flexible twin screw extruder for hot melt extrusion and twin screw granulation.
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The results are very good.
Research in biomaterials
The equipment is effective, however a lot of practice must be had so that the results can be reproducible. The post-sale service I know is good but I could not verify it. The product is extremely expensive for developing countries.
Review Date: 15 Mar 2021 | Thermo Fisher Scientific
The Thermo Scientific Pharma 11 is a unique, flexible twin screw extruder for hot melt extrusion and twin screw granulation.
In the early development of a new drug research and development formulation scientists face the challenge that only a small amount of expensive API (Active pharmaceutical ingredient) is available for experiments.
The Thermo Scientific Pharma 11 extruder provides material and labor effective extrusion capabilities down to 20g/h. Its parallel 11mm twin screws and compact design which is fully scalable with the Thermo Scientific stand alone pharmaceutical compounding systems enables the researcher to obtain process relevant results or even perform small scale production.
Hot-Melt Extrusion Compendium
Hot-melt extrusion (HME) can help achieve the needed high efficacy, overcome bioavailability issues of an active pharmaceutical ingredient (API), and tailor release profiles. HME is a straightforward technique in which solid dispersion of drug particles or molecules in a polymer matrix is achieved. Depending on the processing conditions and the chemical and physical properties of polymers and APIs, different types of dispersions are possible. Explore the versatility of HME, discover what happens when materials are heated, and learn how to design a solvent-free HME process and how to produce different dosage forms.
