MaxPeak premier SEC columns
Size-based separations of peptides, proteins, and viral vectors
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Get unmatched batch-to-batch reproducibility with the wide range of Waters Size-Exclusion Chromatography (SEC) Columns and standards for protein and peptide characterization.
SEC is a powerful technique for aggregate and fragment analysis in the research, development, and manufacturing of biotherapeutic proteins, such as insulin and monoclonal antibodies (mAb). With SEC, also known as gel filtration, you can separate proteins based on their size (hydrodynamic radii versus absolute molecular weight) in solution, with larger sized species eluting before smaller proteins.
The pore size and volume of the SEC particles used in the packed column drives this isocratic based technique, so the column you choose matters. As the molecular weight of the proteins of interest increases, SEC columns with comparatively larger pore size particles are selected.
Analytical workflow solutions for PFAS analyses
Environmental contamination by per- and polyfluoroalkyl substances (PFAS) and rising concerns about its long-term impacts on the general population, have increased the urgency for wider PFAS analysis. Initially the focus was solely on environmental matrices but has now expanded into food analysis due to the risk to consumers. Accordingly, regulations and guidance documents have been released to assure the quality of water bodies, drinking water and most recently also for food and feed. Here, Waters describes the workflow of its sample-to-result approach for PFAS analysis that can be incorporated into any lab whether the focus is food, water or environmental.
