These "5-Donor" Human Plateable Hepatocytes are a pooled population of primary hepatocytes produced by combining cells from 5 individual donors in a single vial. Pooling donors helps to minimize lot-to-lot variation and improves predictability of drug metabolism studies and other biological assays.
• Pure, highly viable, plateable hepatocytes
• Lot-specific characterization data
• Thawing and plating process compatible with existing protocols
Consistent cell attachment
These high-quality plateable primary hepatocytes have in vivo-like enzyme expression levels and proper cell morphology, with such in vitro vs. in vivo correlations helping enable more sound decisions regarding the fate of compounds being tested.
5 donors in a single vial
The cells are provided in a cryopreserved format similar to single donor plateable hepatocytes and have been shown to have approximately equal representation of each donor when plated.
Every lot of pooled plateable hepatocytes is tested for Phase I enzyme activity, cell viability, plating efficiency, and morphology.