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Fibra-Cel disks are a solid support material for the growth of mammalian, animal and insect cells. Animal cells such as hybridoma, insect and various anchorage-dependent recombinant cells have all been successfully grown using Fibra-Cel.
Fibra-Cel is manufactured according to cGMP guidelines and is composed of polyester non-woven fiber and polypropylene. Fibra-Cel disks are also treated electrostatically to facilitate suspension cells adhering to the disks and becoming trapped in the fiber system, where they remain throughout the process. The disks are predominately used as a matrix for the growth of cells when secreted products are desired.
Cell density and productivity achieved with cells grown on Fibra-Cel disks can be up to ten times higher than anchorage-dependent cells growing on microcarriers (or yields of suspension cultures). Currently researchers are reporting growth for most cell lines of 108 cells per cm3 of bed volume.