DNA Clean & Concentrator™-5 by Zymo Research

Manufacturer Zymo Research  |   Model: D4003
4.7
/
5.0
  |  29 reviews
The DNA Clean & Concentrator™-5 cleans and concentrates up to 5 µg of DNA in as little as 2 minutes.


DNA Clean & Concentrator™-5 by Zymo Research product image
DNA Clean & Concentrator-5 PCR Clean-up Kit
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Average Rating: 4.7
29 Scientists have reviewed this product

5 out of 5
Ease of use
5 out of 5
After sales service
5 out of 5
Value for money


  • Status:

    Reviewer
  • Member since: 2019

  • Organization: University of Utah



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Fast, easy cleanup.
Rating: 5.0

  • Application Area: Cleanup of gDNA from fecal DNA extractions

"My gDNA fecal extractions were low concentration and pretty contaminated, instead of doing them again I used this cleanup kit which was fast, easy, and worked like a charm. All my samples had a good concentration for sequencing after using this kit!"

Review date: 06 Jun 2019 | DNA Clean & Concentrator™-5
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: University of Florence, Dept of Health Science



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    3 out of 5
Very good reaults.
Rating: 4.0

  • Application Area:Molecular biology, genomics, gene expression analysis

"Easy to use, allows you to concentrate samples without affecting the quality of the sample (differently to methods that use warming)."

Review date: 06 Jun 2019 | DNA Clean & Concentrator™-5
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: CASPR Bio



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Great results! I always prefer Zymo on my bench.
Rating: 5.0

  • Application Area:Purification of PCR products

"It's a great product. Easy to use and very useful because we need to concentrate PCR products for our validation of sensitivity in-vitro and it really works well. In addition, the kit conserves the quality of the DNA. Excellent balance between price and quality. I would choose it every time!"

Review date: 05 Jun 2019 | DNA Clean & Concentrator™-5
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: Huntsman Cancer Institute



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Best yields of all cleanup kits we have tried.
Rating: 5.0

  • Application Area:Clean up PCR and DNA samples for downstream applications

"A very simple protocol and reliable results. We get the best yields from this kit."

Review date: 05 Jun 2019 | DNA Clean & Concentrator™-5
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: CITY OF HOPE



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Great value and very consistent results.
Rating: 5.0

  • Application Area:Clean up of DNA (e.g. after ChIP or cloning)

"The DNA Clean & Concentrator-5 is a great product that removes the need to carry out lengthy precipitations for routine DNA clean up. It is easy to use and allows you to elute in very low volumes with high yield and good purity values. Would recommend to everyone."

Review date: 05 Jun 2019 | DNA Clean & Concentrator™-5
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: University of Louisville



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Great product, great value, must have!
Rating: 5.0

  • Application Area:Purification of PCR products directly from reactions; purification after restriction digests

"This is a very easy way to clean up DNA fragments from a variety of upstream applications (PCR, restriction digests, etc). We get good yield and clean products for downstream steps. We even used this once to purify a radiolabelled probe away from unincorporated nucleotides."

Review date: 05 Jun 2019 | DNA Clean & Concentrator™-5
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: City of Hope



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Great value.
Rating: 5.0

  • Application Area:Purify products for cloning

"Kit is easy to use. Process is quick and yields clean product for downstream applications."

Review date: 05 Jun 2019 | DNA Clean & Concentrator™-5
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: IQB, the University of Tokyo



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    3 out of 5
Great product!
Rating: 3.7

  • Application Area:Pretreatment of NGS DNA sample

"Zymopure series columns work very well. Elution volume can be kept at low amount. Our DNA prep methods require concentration steps for NGS library prep. Hopefully, this kit will be cheaper in Japan."

Review date: 05 Jun 2019 | DNA Clean & Concentrator™-5
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: ICR



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Great product, just what we needed to process samples in unknown elution buffer!
Rating: 5.0

  • Application Area:DNA buffer replacement

"Great product, easy to use and implement. DNA recovery rate is high. Perfect for concentrating your DNA sample for low volume input assays, as well as buffer replacement tool when processing samples eluted in unknown buffer, and your downstream assays require low EDTA or salt content."

Review date: 05 Jun 2019 | DNA Clean & Concentrator™-5
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: The University of akron



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Budget PCR purification.
Rating: 5.0

  • Application Area:Zebrafish cell culture

"Easy to use, gets the job done. Cheapest kit that I could find among competitors. Purifies PCR products >100bp flawlessly (and quickly; <5mins). I recommend this product"

Review date: 05 Jun 2019 | DNA Clean & Concentrator™-5


  • Status:

    Reviewer

  • Member since: 2019

  • Organization: Molecular BioSciences



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Very good kit!
Rating: 5.0

  • Application Area:Gene expression profiling, library preparation for NGS

"Easy-to-use, provides reproducible results. Perfect for low amounts in combination with class CI columns."

Review date: 05 Jun 2019 | DNA Clean & Concentrator™-5
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: University Hospital Essen



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
Excellent clean-up system. I love it!
Rating: 4.7

  • Application Area:Concentration of nucleic acids, clean-up of PCR fragments for T7-Assay

"This product is easy to use, straight-forward and requires only a minimum amount of time. It always works - which is not true for many other clean-up systems! Elution in quite small volumes is really cool."

Review date: 05 Jun 2019 | DNA Clean & Concentrator™-5
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Loyola University Chicago



  • Ease of use
    5 out of 5
    After sales service
    2 out of 5
    Value for money
    3 out of 5
Great product but overpriced
Rating: 3.3

  • Application Area:Clean up of amplicons for sequencing

"I didn't need to contact after sales service so please ignore my rating for the service. This is a convenient and simple product to use. It is very expensive considering the simplicity of the product."

Review date: 18 Aug 2016 | DNA Clean & Concentrator™-5
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Institute for Molecular Medicine Finland FIMM



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
Easy to use, great worth for money!
Rating: 4.7

  • Application Area:Clean up samples for NGS analysis

"The product is very easy to use and it is very affordable price."

Review date: 08 Aug 2016 | DNA Clean & Concentrator™-5
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: UCSF



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
Quick way to clean your DNA samples
Rating: 4.3

  • Application Area:Molecular Bio

"Very quick protocol. Gives fairly good results and clean DNA"

Review date: 29 Jul 2016 | DNA Clean & Concentrator™-5
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Biotech



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
Pretty good
Rating: 4.7

  • Application Area:DNA Clean up

"Easy to use, quick and simple prep that yielded decent results."

Review date: 29 Jul 2016 | DNA Clean & Concentrator™-5
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Georgia Tech



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
Good clean DNA for downstream uses but some loss of sample.
Rating: 4.3

  • Application Area:DNA cleanup

"The kit was easy to use and produced good clean DNA samples that we could use for NGS sequencing. There is considerable loss of sample so the kit requires a decent starting concentration of DNA but we were able to clean-up samples that we could not clean with more traditional methods (phenol extraction/ethanol precipitation)."

Review date: 29 Jul 2016 | DNA Clean & Concentrator™-5
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: University of Alberta



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
Great price, high quality.
Rating: 4.3

  • Application Area:DNA purification

"I bought it because of its great price. After use, I found it have the same quality with Qiagen similar product."

Review date: 28 Jul 2016 | DNA Clean & Concentrator™-5
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: IRCC Candiolo



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Say goodbye to your contaminated DNA.
Rating: 5.0

  • Application Area:Purification of DNA from contaminant

"I used this product to clean DNA extracted from FFPE tissue and highly contaminated with phenol according to the spectrophotometer profile (ultra low 260/230 ratio, and 260/280 close to 1). The kit allowed to removal of all the contaminant, getting perfect 260/230 and 260/280 without major loss of template according to quantification via Qubit. The protocol is easy, as usual with products from Zymo, and the different parts of the kit can be bought separately. The elution can be restricted to a very low volume, allowing concentration of the template. The only negative aspect, is the necessity to use an elution buffer with pH>7 such as tris which my NGS facility does not accept."

Review date: 27 Jul 2016 | DNA Clean & Concentrator™-5
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: UW



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Great kit for NGS libraries prep.
Rating: 5.0

  • Application Area:NGS library prep

"Recovery efficiency is high. Ease of use and better value at price comparing to QIAGEN MinElute PCR Purification Kit. Helpful, friendly, and immediate online tech support, should you have any questions."

Review date: 27 Jul 2016 | DNA Clean & Concentrator™-5
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: University of Florida



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
All post extraction steps in one product.
Rating: 5.0

  • Application Area:Cleaning metagenomic DNA.

"All the Zymo products I've used, including the DNA Clean & Concentrator™-5, are phenomenal. I work with very dirty samples - marine microbialites - contaminated with salts, extra polymeric substances, sediments, proteins, and, after collection, the preservative RNAlater. Zymo DNA and RNA Clean and Concentrator is the only product like it that has successfully cleaned my samples of all the contaminants remaining after extraction, including the phenol that carries over from the extraction itself. Additionally, my samples are very low in nucleic acid yield, so the added benefit of having one product to clean and concentrate means that I lose less material in downstream steps. I can even do a DNase treatment in the RNA C&C-5 kit. I'm very happy with Zymo's products."

Review date: 26 Jul 2016 | DNA Clean & Concentrator™-5
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Stanford University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    3 out of 5
Fairly effective. Seems like a good option for removal of plant PCR inhibitors.
Rating: 4.3

  • Application Area:Isolation of DNA from root tips (fungal amplification).

"This kit was very easy to use, and had a straight forward protocol. Post cleaning DNA showed significant improvement in amplification."

Review date: 25 Jul 2016 | DNA Clean & Concentrator™-5
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Biotech



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
Pretty good
Rating: 4.7

  • Application Area:DNA Clean up

"Easy to use, quick and simple prep that yielded decent results."

Review date: 25 Jul 2016 | DNA Clean & Concentrator™-5
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: UC Riverside



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
Great value for a fair price.
Rating: 4.7

  • Application Area:Purification of PCR product or digested plasmid for cloning.

"Product is easy to use and yields are good. The protocol is also fast."

Review date: 22 Jul 2016 | DNA Clean & Concentrator™-5
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: NWP



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Great value, works just as well or better than similar more expensive kits.
Rating: 5.0

  • Application Area:Preparing PCR products for sequencing

"I've been working in laboratories for many years and have had the chance to use many different PCR cleanup kits. I was able to get a free sample of the Zymo DNA clean & concentrate kits to prepare my PCR products for sanger sequencing. They worked great, and were much less expensive to use than my previous kit. The DNA clean & concentrate kits are very easy to use. One added feature that I really appreciated is that you can buy all of the kit components separate so if you have extra buffers you can just order more columns to stretch your dollar even more. I highly recommend this product."

Review date: 21 Jul 2016 | DNA Clean & Concentrator™-5
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Massachusetts General Hospital



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Easy to use and it does not require a lot of time.
Rating: 5.0

  • Application Area:DNA purification.

"Really easy to use, instructions are super clear, and is a fast method to clean DNA for sequencing. The price is super affordable."

Review date: 20 Jul 2016 | DNA Clean & Concentrator™-5
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: EntoGenetics Inc.



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
A lab staple.
Rating: 5.0

  • Application Area:PCR and digest cleanup

"These clean and concentrate cartridges do just that. They take and DNA prep, remove everything else and put it out in a few micro liters. They are well priced, easy to use, and the quick protocol is just the same with every sample. We keep them stocked in the lab to grab anytime there a a prep to be cleaned, enzyme removed, buffer changed, or just reduced in volume."

Review date: 13 Jul 2016 | DNA Clean & Concentrator™-5
  • Status:

    Advanced Reviewer

  • Member since: 2016

  • Organization: Florida State University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Great quality and easy to use
Rating: 5.0

  • Application Area:DNA purification during NGS sample prep

"This product allows elution of purified DNA into small volume in a great quality. The purification process is very fast. Each component of the kit can be purchased separately, which is very convenient and environment friendly."

Review date: 13 Jul 2016 | DNA Clean & Concentrator™-5
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Carnegie Institute for Science



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Fast, high efficiency and reproducible
Rating: 5.0

  • Application Area:Recovery of DNA from ChIP samples

"This product design is much better than QIAGEN and can efficiently recovery small amount of DNA in less than 10ul, adaptable for downstream application. Fast process and high yield "

Review date: 12 Jul 2016 | DNA Clean & Concentrator™-5

The DNA Clean & Concentrator™-5 product provides purification of up to 5 µg DNA from PCR, endonuclease digestions, DNA modification reactions, isotope/fluorescence labeling reactions, etc.

This product facilitate the removal of DNA polymerases, modifying enzymes, RNA polymerases, ligases, kinases, nucleases, phosphatases, and restriction endonucleases, as well as free dNTPs and their analogs including radiolabeled and fluorescent derivatives. Eluted DNA is suitable for PCR, arrays, ligation, sequencing, etc.