Disc1 Knockout Rat by SAGE Labs
This model contains a biallelic deletion within the Disc1 (disrupted in schizophrenia 1) gene, encoding the DISC1 protein.
A translocation disrupting Disc1 was discovered to co-segregate with major psychiatric illness in a Scottish family. This model is useful in the study of schizophrenia.Disc1 Knockout Rat Characteristics:
Disc1 is involved in neuronal growth and cortical development
The protein also regulates the proliferation of embryonic and adult neuronal progenitor cells through th... Read more