Corning® Matrigel® Basement Membrane Matrix, LDEV-free, 5 mL by Corning Life Sciences

Manufacturer Corning Life Sciences  |   Model: 356234  |  Available in North America, Western Europe, Asia, Eastern Europe, Middle East, Africa
Corning Matrigel matrix is a solubilized basement membrane preparation extracted from the Engelbreth-Holm-Swarm (EHS) mouse sarcoma, a tumor rich in extracellular matrix proteins, including Laminin (a major component), Collagen IV, heparan sulfate proteoglycans, entactin/nidogen, and a number of growth factors.Quality Mouse colonies are routinely screened for pathogens via Mouse Antibody Production (MAP) testing Extensive PCR testing is performed to screen for a number of pathogens, including ... Read more


Corning® Matrigel® Basement Membrane Matrix, LDEV-free, 5 mL by Corning Life Sciences product image
Corning® Matrigel® Basement Membrane Matrix, LDEV-free, 5 mL
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Corning Matrigel matrix is a solubilized basement membrane preparation extracted from the Engelbreth-Holm-Swarm (EHS) mouse sarcoma, a tumor rich in extracellular matrix proteins, including Laminin (a major component), Collagen IV, heparan sulfate proteoglycans, entactin/nidogen, and a number of growth factors.

Quality

  • Mouse colonies are routinely screened for pathogens via Mouse Antibody Production (MAP) testing
  • Extensive PCR testing is performed to screen for a number of pathogens, including LDEV, to ensure strict control of raw materials used during the manufacturing process
  • Tested and found negative for bacteria, fungi, and mycoplasma
  • Protein concentrations are determined by Lowry method
  • Endotoxin units are measured by Limulus Amoebocyte Lysate assay
  • Corning Matrigel Matrix gel stability is tested for a period of 14 days at 37°C
  • Biological activity is determined for each lot using a neurite outgrowth assay. Chick dorsal root ganglia are plated on a 1.0mm layer of Corning Matrigel Matrix and must generate positive neurite outgrowth response after 48 hours without addition of nerve growth factor
  • Source

Engelbreth-Holm-Swarm Mouse Tumor

Preparation and Storage
Store at -20°C. Avoid multiple freeze-thaws. Do not store in frost-free freezer. KEEP FROZEN.

Application

  • Cell Growth and Differentiation
  • Metabolism/Toxicology Studies
  • Invasion Assays
  • in vitro and in vivo Angiogenesis Assays
  • in vivo Angiogenesis Studies and Augmentation of Tumors in Immunosuppressed Mice
  • for Corning Matrigel Lot Selection and Reservation.

For Customers in California only: WARNING Please refer to Safety Data Sheet (SDS) Section 15 or Letter in Lieu for more information regarding California Proposition 65.

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Product Overview

Corning® Matrigel® Basement Membrane Matrix, LDEV-free, 5 mL by Corning Life Sciences product image

Corning® Matrigel® Basement Membrane Matrix, LDEV-free, 5 mL

Manufacturer Corning Life Sciences  |  Available in North America, Western Europe, Asia, Eastern Europe, Middle East, Africa

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