Chirascan™ Circular Dichroism Spectrometer by Applied Photophysics Ltd

4.8
/
5.0
  |  3 reviews
High Performance - Ready to Run


Chirascan™ Circular Dichroism Spectrometer by Applied Photophysics Ltd product image
Chirascan™ Circular Dichroism Spectrometer
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Average Rating: 4.8
3 Scientists have reviewed this product

5 out of 5
Ease of use
5 out of 5
After sales service
5 out of 5
Value for money


  • Status:

    Advanced Reviewer
  • Member since: 2016

  • Organization: University of Saskatchewan



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Great equiiment to check secondary folding.
Rating: 5.0

  • Application Area: Protein chatacterization

"CD is very easy to use. Interchangable cuvettes holder will allow to scan very wide protein concentrations. Detector is tuned to 1150-160nm which is great if you want to use for kinetics . Sample holder can be temp controlled from 5-95C and will allow to check protein stabilitt/melting. Lamp is amazing and vary stable, the same goes with monochromator. Data is used in provided software which makes it easy to detect melting points. After care is great and team is very responsive to your needs. You will have to use purest nitrogen available 5.0 (99.999%) to take good care of the optics."

Review date: 05 Apr 2019 | Chirascan™ Circular Dichroism Spectrometer
  • Status:

    Reviewer

  • Member since: 2018

  • Organization: weizmann institute



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
Very good instrument - critical for my research and others.
Rating: 4.7

  • Application Area:Chiral spectroscopy

"A very effective and easy to use instrument - the reults are reliable accuratte and reprocudible. It is a major asset in structure determination of organic-biologic samples, proteins and peptides, and also for several other research areas. A sturdy instrument, not prone to technical problems. It is used regularly."

Review date: 23 Mar 2019 | Chirascan™ Circular Dichroism Spectrometer
  • Status:

    Reviewer

  • Member since: 2018

  • Organization: ETH Zürich



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
Very good service.
Rating: 4.7

  • Application Area:Analyze secondary structure of peptides

"Service both via email and on-site was very quick, professional and helpful. All employees are very friendly and pleasant to work with."

Review date: 01 May 2018 | Chirascan™ Circular Dichroism Spectrometer

Suitable for studying chiral molecules of all types and sizes, this Chirascan CD spectrometer has featured in thousands of publications since its introduction in 2005. Often used to analyze biomolecules, Chirascan data contributes to a deeper understanding of biomolecular characteristics, mechanisms and interactions.

When sensitivity and accuracy are key, our Chirascan V100 model (formerly Chirascan-plus) ensures that researchers can get the most from every CD analysis.  

More than α-helix and β sheet - Determine structural and thermodynamic properties

  • Gain insight and detect changes in secondary and tertiary structure
  • Determine response to thermal or chemical change
  • Study folding and unfolding mechanisms
  • Expand capabilities with dedicated Chirascan accessories

Ready to run

Chirascan systems are supplied with the features and accessories required for acquisition of high quality data from ‘day one’.

Component Highlights

Molecular Sieve, Activated Charcoal Filter

  • Removes common gas impurities

Active Nitrogen Management System

  • Regulates purge gas consumption
  • Software-controlled

Air-Cooled Xenon Lamp

  • Software-controlled
  • Up-time recorded

Monochromator

  • Dual polarizing prisms maximize light ­throughput
  • Produces horizontally, linearly polarized monochromatic light

Photoelastic Modulator

  • Converts horizontally polarized light into circularly polarized light. Alternates between left- and right-handed circular polarized light

Temperature-Controlled Sample Chamber

  • Consistent analytical conditions
  • Continuous temperature ramps
  • Temperature measured directly in sample

Water Circulator

  • Dissipates heat from sample chamber and sample storage Peltiers

Photomultiplier Detector

Cuvettes and Holders

  • Selected for far- and near-UV CD analysis of biomolecules (single sample mode)

Control and analysis software

  • Easily defined run parameters and store routine protocols
  • Saves time with scheduled start-up/shutdown of lamp and N2 supply
  • Fail-safe lamp switch-off if N2 flow drops
  • Ensures O2-free conditions with N2 purge
  • Recognizes flow cell to select optimal run/wash/dry protocol