Member since: 2019
Organization: UT Health Science Center, San Antonio
So far it is good.
Application Area: Sonication, I POND, ChIP
"We just bought the Bioruptor, so far it is good."
Member since: 2016
Organization: University of Texas MD Anderson Cancer Center
Reproducible results every time
Application Area:Sonication for ChIP-seq-eq
"Very easy to use, no worries about the heating, high throughput."
Member since: 2016
Organization: High Point University School of Pharmacy
Great Instrument and considered a must have in our lab.
Application Area:Extraction of protein & RNA/DNA from small volume tissue samples for downstream analysis.
"Easy setup and straightforward to operate. Great technology in that it keeps your samples at low temps during sonication/homogenization of tissues and is high efficiency. Process is contained within each tube so there's no risk of cross-contamination."
Member since: 2015
Organization: Postdoctoral Associate in Cambridge MA
A must have when performing ChIP
Application Area:Tissue Homogenization for ChIP
"Excellent instrument for DNA shearing from tissue. Had attempted using a sonicator which destroyed my DNA and protein. The Bioruptor consistently sheared my DNA to an appropriate size and did not disrupt the protein."
The Bioruptor® uses a unique system to uniformely process multiple samples in sealed tubes of 0.5 ml to 50 ml capacity. An excellent device for shearing chromatin or DNA, cell and tissue disruption and many other applications.
Diagenode’s Bioruptor® Plus uses a gentle method of sonication to retain the integrity of DNA and/or biological complexes, including chromatin, protein-protein binding, protein-DNA complexes and other biochemical and biological assay systems. The Bioruptor® Sonication System uses a sonication bath to generate indirect sonication waves, which emanate from an ultrasound element below the water tank. Because the system is gentler than other sonicators, the Bioruptor® produces better and more consistent results than with harsher sonication methods. Up to 12 closed tubes can be sonicated in parallel and the continuous rotation of tubes allows even distribution of the energy for efficient sonication. The Bioruptor® enables automation of sonication, guaranteeing higher reproducibility of results.