Status:
ReviewerMember since: 2022
Organization: Enzene Biosciences Limited Pune
Great instrument every labs should have one
Application Area: analysis of Peptide API Samples to determine water content
"KF Coulometer is good for handling and results are also reproducible. It is used for low water content samples . KF coulometer is easy to use in daily routine, space saving because it works without PC and high quality for less money in compare with others just having problem with connecting the scale via USB easy to learning for new user .Hardware is also good material."
Status:
ReviewerMember since: 2022
Organization: Enzene Bioscience Ltd. Bhosari pune
Great results & satisfactory smile on customer face on time service.
Application Area:water content
"We have KF instrument 860 KF Thermoprep ,831 KF coulometer & this is nice product & engineer service. Great quality results or reproducible results . This instrument is easy to use or operate. Metrohm engineer on time service & mail communication regarding preventive maintains."
Status:
ReviewerMember since: 2022
Organization: Quay Pharma
Machine works ok but many issues
Application Area:Measuring water content in a variety of samples
"The equipment is easy to use and sample prep does not take up too much time, however the variety of issues that I have had with the equipment outweighs its usefulness, and there is a list of error codes in the handbook which describe some errors that may occur but no real aid in fixing them. Admittedly one of the reoccurring issues is to do with an external standard, but we've been told by engineers that the machine is working perfectly when it is not."
Status:
ReviewerMember since: 2022
Organization: Quay Pharmaceuticals
Top notch kit.
Application Area:Determination of water content in APIs pre and post formulation
"The equipment is straightforward to use from a basic user level, creating a new method is simple and the result reproducibility is strong. These points in tandem make our method development process a dream. I would highly recommend this product for any Laboratory that is looking to measure water content."
Status:
ReviewerMember since: 2022
Organization: SGS
Well worth the money spent, would always recommend.
Application Area:Analyze APIs post formulation
"Results are consistent, accurate and the kit is very reliable. Makes my job so much easier knowing I can trust the kit I use everyday. Easy to use and trustworthy."
Status:
ReviewerMember since: 2018
Organization: Innovotech
Easy to use and a must have for our lab.
Application Area:water content
"The materials we test cannot be directly injected for Karl Fischer measurement of water content, and this oven makes it possible. We looked at ovens from other companies, but their design made no sense, particularly if you want to measure very small quantities of water. This was really the only reasonable option. The oven is very straightforward to use, and comes with great technical support. It's expensive, but the only design we found worth purchasing."
Status:
ReviewerMember since: 2021
Organization: Ashland Specialties Ireland Ltd.
Accurate and precise results for bioresorbable polymers!
Application Area:R&D and GMP manufacturing analyses - water content in bioresorbable polymers
"Bioresorbable polymers are degraded by hydrolysis, therefore the water content is of great importance from an R&D, GMP and Quality standpoint, especially in the biomedical and medical device industry. Using the 860 KF Thermoprep we can achieve precise and accurate results, giving us a lot of confidence and reproducibility in our analyses. It is easy to use from technicians to scientists, very easy to clean and keep the maintenance in order thanks to the guidance and support from Metrohm UK Technical support, they have helped us from method optimization to troubleshooting. I would definitely recommend this device and the technical service, with this combination you should have your equipment up and running in no time and you will start doing analysis before you know it."
Status:
ReviewerMember since: 2020
Organization: Westrac
Great instrument compared to the competition. However, servicing cost is expensive.
Application Area:Oil lab
"Metrohm has a very quick TAN/TBN titrator. However, parts are very expensive. The instrument is very robust and easy to maintain."
Status:
ReviewerMember since: 2019
Organization: Gnosys Global Limited (A Kinectrics Company)
Good investment and addition to our analytical facility
Application Area:Polymer, nanocomposites, composites, dielectric fluids
"The installation of the equipment is very simple and straight forward and requires low maintenance. The temperature control is very precise, and the system could be ready for sample analysis in very quick succession. Building a temperature method is very simple and the available brochures and manuals for guidance are properly described for the user. The equipment has a small footprint on the lab desk, which is admirable to accommodate in small space. I didn't like the display screen on the equipment. It is very dark and has no backlight for illumination. That should be improved. A proper keypad is also recommended to have in next version of the equipment. There is a plastic connector fitting for gas purging which should be replaced by metal connectors for better durability. On the first day the plastic connector fitting was broken at our site and we couldn't use the equipment for at least a month while waiting for the replacement. Another request to Metrohm would be to reduce the price of the sample vials to an affordable range as it is now very expensive."
Status:
ReviewerMember since: 2011
Organization: Metrics, Inc.
"This unit has been very useful in the laboratory. The service from the vendor has been excellent. As with most new equipment, the ease of use can be directly related to training and involves a learning curve."
For various reasons many substances are not suitable for a direct Karl Fischer titration:
– They release their water only slowly
– The water is released at high temperatures only
– The substances are poorly soluble in alcohols
– They undergo side reactions with KF reagents
– They contaminate the titration cell or the electrodes
By using the KF oven method the above-mentioned problems can be avoided. The substance under investigation is heated in a hermetically sealed vial in the oven. The water vapor released is transferred to the titration cell by a carrier gas. This means that no noxious solubilizers have to be used, side reactions as well as matrix effects are absent and the contamination of the titration cell is avoided.
Depending on the sample’s water content, the determination can be carried out either by coulometric or volumetric Karl Fischer titration.