6546 LC/Q-TOF by Agilent Technologies

Manufacturer Agilent Technologies  |  Available Worldwide
  |  1 reviews
Quadrupole Time of Flight LC/MS

6546 LC/Q-TOF by Agilent Technologies product image
6546 LC/Q-TOF
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Average Rating: 5.0
1 Scientist has reviewed this product

5 out of 5
Ease of use
5 out of 5
After sales service
5 out of 5
Value for money

  • Status:

  • Member since: 2014

  • Organization: University of Colorado

  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Most accurate instrument in the market!
Rating: 5.0

  • Application Area: Analytical chemistry (Environmental)

"I have been using accurate mass instruments for the last 20 years. The last model (Quadrupole-time of flight 6546) is the most accurate I have ever seen, and sensitive too! We use it both for quantitation purposes and for screening environmental contaminants."

Review date: 24 Dec 2020 | 6546 LC/Q-TOF

The 6546 LC/Q-TOF accelerates your lab’s capabilities by enabling comprehensive workflows in metabolomics research, food safety, food authenticity, and environmental screening. With simultaneous high sensitivity, wide dynamic range, high resolution, isotope fidelity and accurate mass measurements the resulting high data quality provides the level of confidence you need for fast and simplified data review processes.

With Q-RAI Quadrupole resolved All Ions or All Ions acquisition, food safety screening can now be combined with fragment information for identification, allowing you to conduct target and suspect screening simultaneously. In addition, for metabolomics research, the resolution increase together with broad dynamic range and isotopic fidelity makes the 6546 LC/Q-TOF the ideal platform.


  • Gain confidence at the low and high concentrations with simultaneous delivery of 5 orders of in-spectrum dynamic range and mass resolution over 60k (for high masses) and over 30k (for low masses)
  • Narrow down identification possibilities through sub-ppm mass accuracy and isotope fidelity within 5%
  • Maintenance made easy with vent-free access to ion source and inlet
  • Move beyond analytical targeted screening restriction on number of compounds and time-consuming method maintenance with accurate mass spectral libraries for pesticides, veterinary drugs, mycotoxins, extractables and leachables, and water contaminants
  • Access metabolomics workflows for profiling, lipidomics, and qualitative flux analysis
  • Use the new food authenticity workflow to streamline analysis when testing for product origin or adulteration