2489 UV/Visible Detector
The 2489 UV/Visible Detector is a versatile, dual-wavelength absorbance detector for HPLC. This detector offers the high sensitivity required for routine UV-based applications to low-level impurity identification and quantitative analysis. The 2489 UV/Visible detector’s extended linear range of 2.5 AU makes for easy quantitation of both major and minor components in the same run. You can also simultaneously monitor absorbance…
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Great product from Waters. Using for years on and on....
Pharmaceuticals and chemical substances
The detector is extremely sensitive to detect even trace level impurities. Compact in size and very rugged for routine use.
Review Date: 20 Feb 2019 | Waters
It's efficient and is not expensive
Analyze drugs in a third authorized laboratory
This detector is very efficient. It has a long duration, we haven't find any trouble using it carefully. In all the chromatographs we give some maintenance of maximum once a year, because of bad practices when the mobile phase is not filtered. It Is very resistant and we can buy some parts at an accessible price.
Review Date: 25 Sept 2018 | Waters
The 2489 UV/Visible Detector is a versatile, dual-wavelength absorbance detector for HPLC. This detector offers the high sensitivity required for routine UV-based applications to low-level impurity identification and quantitative analysis.
The 2489 UV/Visible detector’s extended linear range of 2.5 AU makes for easy quantitation of both major and minor components in the same run. You can also simultaneously monitor absorbance at two user-selectable wavelengths for more information per run.
Operating as a stand-alone or as an integral component of Waters HPLC Systems, the 2489 UV/Visible detector will enhance the productivity of your chromatography laboratory. It offers a wide range of flow cell options and integrated features:
• Enhanced sensitivity via patented TaperSlit™ flow cell, which channels light through the cell for better energy throughput while minimizing RI effects
• Low noise performance (<5 µAU)
• Flexible sampling rates, from 1 to 80 Hz, for normal and fast LC separations
• Independent optimization of high-speed data rates and filter time constants allows for the accurate integration of narrow, sharp peaks
• Enhanced thermal wander management reduces baseline wander due to fluctuations caused by ambient conditions
• Accessible detector components for easy operation and maintenance
Increasing Specificity and Sensitivity in Routine Peptide Analyses Using Mass Detection with the ACQUITY QDa Detector
Often in protein based biotherapeutics development peptides are analyzed to assess the quality of candidate molecules using optical based assays. While this provides acceptable results orthogonal detection techniques, such as mass detection, can improve specificity, expand detection limits and increase confidence about peak homogeneity. In this application note Waters demonstrate the ACQUITY QDa Detector for the acquisition of optical and MS-based data.
Isolating Trace Impurities for Structural Elucidation in a Commercial Fungicide Formulation Using Preparative SFC
Trace impurities in synthetic products that interact with human end users or may have an undesirable environmental fate are regulated by various government agencies such as FDA and EPA. As a result, impurity separation and their structural identification are important research functions for many industries, including pharmaceutical, agrochemical, food, and consumer products. This application note describes a workflow to achieve full structural elucidation of trace impurities that can be implemented using preparative supercritical fluid chromatography to isolate trace impurities.
