Products & ReviewLife Sciences
VivopureX™ Antibodies for In Vivo Research
Absolute Antibody LtdAvailability: North America, UK/EU, EMEA, and APAC
VivopureX™ antibodies are recombinant mouse antibodies ideal for in vivo research in mouse models. The collection consists of popular antibody clones, many originally obtained from rats or hamsters, which Absolute Antibody has engineered into mouse-anti-mouse recombinant versions to improve research results.
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These species-matched chimeric antibodies consist of a clone’s original antigen-binding variable domain with a mouse constant domain.
Absolute Antibody VivopureX™ recombinant mouse antibodies offer many advantages compared to the original antibody format, including:
- Reduced immunogenicity: no neutralizing antibodies are induced in the host organism, meaning the antibody works for longer and cohorts respond more consistently.
- Tailored effector function: antibody formats have been engineered to suit their most popular application. (Increased Fc receptor binding increases depleting potential, while reduced Fc receptor binding reduces side effects in blocking.)
- Increased potency: less antibody is required to achieve the same response in mouse models.
- Batch-to-batch reproducibility: recombinant production ensures the highest possible reproducibility, and guarantees high purity and low endotoxins (<0.5 EU/mg).
