Thermo Scientific™ Pharma16 Twin-Screw Extruder
Pharma-focused twin-screw extruder for HME process development, formulation optimization, and research-to-pilot scale-up.
Pharma 16 Twin-Screw Extruder
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When pharmaceutical teams need to move from lab feasibility toward process-relevant extrusion development, the Thermo Scientific™ Pharma 16 Twin-Screw Extruder supports HME, twin-screw granulation, formulation optimization, and continuous processing workflows. It helps scientists and process engineers study scale-up behavior while maintaining a pharma-focused workflow.
Pharma 16 is suited to formulation development, clinical development support, and research-to-pilot scale-up. It supports solvent-free processing, reproducible extrusion studies, bioavailability-focused formulation work, and process optimization for HME and TSG applications.
Key benefits:
- Pharma-focused HME and TSG process development
- Supports formulation optimization and research-to-pilot scale-up
- Helps evaluate continuous processing workflows
- Designed for reproducible results and practical process learning.
Hot-Melt Extrusion Compendium
Hot-melt extrusion (HME) can help achieve the needed high efficacy, overcome bioavailability issues of an active pharmaceutical ingredient (API), and tailor release profiles. HME is a straightforward technique in which solid dispersion of drug particles or molecules in a polymer matrix is achieved. Depending on the processing conditions and the chemical and physical properties of polymers and APIs, different types of dispersions are possible. Explore the versatility of HME, discover what happens when materials are heated, and learn how to design a solvent-free HME process and how to produce different dosage forms.
