Swift Accel-NGS® 2S Plus DNA Library Kit (96 reactions)
Optimal sequencing of your cfDNA, FFPE and ChIP DNA
Accel-NGS® 2S Plus DNA Library Kit
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Minimizes bias and supports inputs as low as 10 pg.
Benefits include:
- Exceptional yields from DNA inputs of 10 pg to 250 ng
- Excellent efficiency, data quality, and evenness of coverage
- High complexity libraries for deep sequencing
- No base composition bias from AT-/GC-rich genomes
This is the best choice for users working with cfDNA and degraded FFPE samples as well as conducting ChIP-Seq.
Accel-NGS® 2S DNA Library Kits
The application notes provides an overview of Accel-NGS® 2S DNA Library Kits. Accel-NGS 2S DNA Library Kits produce high quality libraries with an all-inclusive, easy-to-use format. Applications of the Library Kits, including use in sequencing liquid biopsy samples and Pico-Scale ChIP-Seq are also covered.
Understanding NGS Intricacy and Single-Cell Sequencing
The application note describes the sequence coverage performance and preservation of molecular complexity of next generation sequencing (NGS) libraries, generated from human and microbial genomic DNA using Accel-NGS® 2S DNA Library Kits for whole-genome sequencing (WGS) on the Illumina® platform. Comparisons to the leading commercially available methods are also presented.
New Tools for Studying Epigenomes of Clinical Samples
Adam Blattler, a Research Scientist at Active Motif, gave an informative presentation on ChIP-Seq (Chromatin Immunoprecipitation Sequencing) and how it can be performed on FFPE (formalin-fixed, paraffin-embedded) clinical samples. Adam gives a background on epigenetic regulation and histone modification and explains the theory behind ChIP-Seq. He describes how Swift Biosciences have developed a highly sensitivity kit, the Accel-NGS® 2S Plus, which overcomes the problem of low abundance of chromatin, an issue encountered when using FFPE samples. Finally, Adam describes new advancements in ChIP-Seq technology such as enChIP (Engineered DNA binding molecule mediated ChIP), which can identify chromosomal looping.
Accurate De-Duplication of Sequencing Data with New Molecular IDs from Swift Biosciences
Kate Cunningham, PhD, Applications Scientist at Swift Biosciences, introduces the new range of molecular IDs for Accel-NGS® 2S library kits. Hear how the molecular IDs label each individual library molecules, to enable low frequency variant detection, as well as accurate de-duplication of single read sequencing and sequencing from samples with non-random fragmentation. The technology is ideal for applications including whole exome sequencing (WES), deep targeted sequencing, cell-free DNA sequencing and ChIP-Seq.
Advances in Sequencing Technology Facilitate Gene Expression Analyses at the Epigenomic Level
Three leading scientists discuss their research and the benefits of ChIP-Sequencing
