PrimeSurface® 3D culture: Clear, Ultra-low Attachment Plates: 96 well, U bottom plates
Grow Uniform Spheroids with Ultra-low Attachment PrimeSurface® Cell Culture Plate

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PrimeSurface® cultureware are ultra low attachment (ULA) dishes and plates that promote scaffold free, self assembly of spheroid formation. The plates are pre-coated with unique ultra hydrophilic polymer which prevents cells from adhering to plastic surface and enables spontaneous spheroid formation of uniform size and shape.
- Promotes uniform size, single spheroid in each well
- Superior optical clarity
- Compatible with brightfield and fluorescent imaging and confocal microscopy.
- For assays such as cell proliferation, cytotoxity, apoptosis
- For drug screening and regenerative medicine
- Sterile, individually packed
PrimeSurface ultra-low attachment 3D cell culture plates
In this application note, PHCbi discusses how PrimeSurface ultra-low attachment 3D cell culture plates help improve the understanding of physiologically relevant mechanisms that occur in vivo. This application note describes the differences between 2D and 3D cell cultures and highlights how 3D cell cultures provide an alternative way to study organ behaviour in three-dimensional models.
Brightfield and Fluorescence Imaging using 3D PrimeSurface Ultra-Low Attachment Microplates
Culturing cells in 3D provides a more a physiologically relevant approach to biomedical research, enabling the study of microenvironmental changes and interactions in health and disease. In this scientific poster, researchers from New Hampshire demonstrate the development of uniform, self-assemblied spheroids using S-BIO PrimeSurface ultra-low attachment cultureware. The PrimeSurface 96 and 384 ULA plates are also suitable for subsequent brightfield and fluorescent imaging of spheroids, illustrated here with the Cytation 5 multi-mode reader.
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