FlowCellect™ Bivariate Cell Cycle Kit for G2/M Analysis
Millipore’s FlowCellect™ Bivariate Cell Cycle Kit for G2/M Analysis is designed to allow the researcher to easily identify, discriminate, and quantitate cells between the G2 and M-phases of the cell cycle. The kit can be used to perform bivariate analysis to measure cell cycle distributions by discrimination of cell cycle phases without the need of sophisticated software modules or algorithms. Having the ability to distingui…
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Millipore’s FlowCellect™ Bivariate Cell Cycle Kit for G2/M Analysis is designed to allow the researcher to easily identify, discriminate, and quantitate cells between the G2 and M-phases of the cell cycle.
The kit can be used to perform bivariate analysis to measure cell cycle distributions by discrimination of cell cycle phases without the need of sophisticated software modules or algorithms. Having the ability to distinguish cells undergoing mitosis versus cells remaining in G2 phase of the cell cycle provides researchers with a powerful tool to closely monitor cell cycle activity at M-phase which can have a huge impact in studying diseases associated with cell proliferation, apoptosis, and cancer.
All FlowCellect kits are optimized on the bench-top guava® flow cytometry systems, which saves valuable time and sample volume. All cell cycle kits contain optimized fixation, permeabilization, wash, and flow buffers to provide researchers with a complete solution for bivariate analysis of total DNA content versus cell cycle phase markers. With the guava platform and FlowCellect kits, researchers can finally have an easy, reliable and fully validated solution to study complex cell cycle distribution analysis right in the comfort of their own lab.
Multiple Flow Cytometric Approaches for Studying DNA Damage Pathways and Assessing the Level of the Cellular Responses to DNA Damage
Investigation of DNA damage pathways and assessment of the DNA damage levels in cells are extremely important for the study of cancer and developing anti-cancer drugs, as defects in DNA damage pathways can cause cancer and lead to genetic instability and ultimately uncontrolled cell growth. In this scientific poster several assays were successfully used in the evaluation of DNA damaging and anti-neoplastic agents. Their impact on the cell cycle was assessed, which helped elucidate the mechanisms of cell proliferation, apoptosis, and DNA repair, ultimately advancing the study for cancer research.
