Custom Optimer™ Affinity Reagent Development Service
Aptamer Group is a developer of custom Optimer reagents as antibody mimetics for use as tool affinity reagents, in biomarker discovery, as diagnostic reagents and as therapeutic lead candidates.

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Aptamer Group is a developer of custom Optimer reagents as antibody mimetics for use as tool affinity reagents, in biomarker discovery, as diagnostic reagents, and as therapeutic lead candidates. Optimers are optimized aptamers, delivering rapid development with customized binding kinetics, and simple, cost-efficient, scalable manufacture to accelerate your pipeline from discovery and development to commercialization.
Biomarker discovery service
Identifying relevant biomarkers from vast proteomic datasets is a major challenge in drug development. Discover how phenotype-driven discovery simplifies complexity to deliver biomarkers precisely aligned with disease context, tissue specificity, and therapeutic goals. This approach enables faster validation and supports both surface and internal targets, accelerating your path to effective, targeted therapies.
Accelerating your journey to the clinic
Accelerating time-to-clinic is critical for therapeutic and diagnostic success, yet traditional antibody development remains costly and slow. Optimer® binders offer a streamlined alternative, cutting timelines by up to 75%.
Discover how the Optimer® platform enables rapid binder optimization, unlocking novel targets and simplifying development, empowering researchers to reach clinical milestones faster and reduce risk across drug and diagnostic pipelines.
Rapid identification and development of SARS-CoV-2 selective Optimers
In this application note, using rapid in-house Optimer® selection and development processes, Optimer® reagents specific to the SARS-CoV-2 S protein were identified. The flexibility designed within the Optimer® selection process enabled analysis of the viral protein in both open and closed formats for simple assay development and monitoring and detection of live virus.
Monitoring antibiotic concentrations with rapid Optimer-based diagnostic assays
In this application note, aptamer and Optimer® reagents were selected against the antibiotic target, moxifloxacin, and incorporated into a novel electrochemical biosensor platform, for the development of rapid diagnostic assays in a point-of-care format.
Enabling improved bioprocessing solutions with Optimer
Current protein-based affinity ligands are unable to resolve a range of complex protein purification problems. This poster describes several commercial case studies where Optimer® ligands are enabling solutions to these bioprocessing challenges. Download now to discover how Optimer® ligands enable new therapeutic modalities, and improved yields and cost-of-goods.
Rapid identification and development of SARS-CoV-2 selective Optimers™
In this application note, Aptamer Group outlines its high-affinity Optimer reagents for SARS-CoV-2 S1, S2, and nucleocapsid (NC) viral target proteins which promise to improve ELISA performance compared to commercially available antibodies.
Spying on bacteria for rapid diagnostic applications
In this article, Aptamer Group discusses its collaboration with QSM Diagnostics and explains how together they have developed a fast and precise diagnostic platform for a range of diseases.
Optimer™ reagents for the flexible monitoring of small molecules
In this poster, Aptamer Group explains how high-affinity Optimers were developed and demonstrates how novel, single-reagent, gain-of-signal assay format Optimers targeting small molecules can be used for rapid, cost-effective point-of-care and field-based analytical platforms.
Optimer reagents: Novel solutions driving discovery
In this infographic, discover the benefits of fully optimized aptamers that are target specific, structurally stable and cost effective. This Optimer™ technology can be used in a range of different applications and assays including ELISA, IHC, LFD and affinity purification to enhance diagnostic and therapeutic research.
Aptamer Group grants Alphazyme the right to incorporate Optimer into hot-start PCR and NGS product formulations
Non-exclusive OEM license grants worldwide rights for Optimer binder in molecular biology applications
Licensing agreed for Optimer as novel vaccine adjuvant
Successful project delivery of Optimer binders with proven function as vaccine adjuvants
Agreement to explore Optimer vehicles for targeted delivery of siRNA
New collaboration will evaluate Aptamer’s fibrotic liver delivery vehicles with siRNA
Aptamer and Timser deliver first cervical cancer blood test
Optimer binders will be developed for use in a cervical cancer blood test
Aptamer Group partners with top five global pharmaceutical company to support innovative vaccine development
Partnership includes initial upfront payments and will potentially deliver recurring revenues for over 10 years
























