Automatic Developing Chamber 2 (ADC 2)
The key to reproducible results by development under standardized conditions
CAMAG® Automatic Developing Chamber 2 (ADC 2)
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Less maintenance and reproducible results
Drug Analysis
Camag Automatic Development Chamber 2 is very versatile equipment required for every analysis. The Rf value of components gets affected by the humidity changes, non-uniform development, and variable development distance. The ADC2 is maintaining the humidity at a constant value, uniform development, and accurate development distance every time. That all results in reproducible results. Camag is developing the HPTLC technique to the new height.
Review Date: 26 Sept 2022 | CAMAG
Important device for stability studies.
Stability studies of phyto pharmaceuticals
For a good reproducibility of the TLC fingerprints of herbal products, it is important to control all the development parameters, especially the humidity. For that, the ADC from CAMAG works really well.
Review Date: 9 Nov 2020 | CAMAG
Development is the most critical step of High-Performance Thin-Layer Chromatography. The Automatic Developing Chamber 2 (ADC 2) is an instrument for reproducible development, performing the development step fully automated, and independent of environmental effects. The activity and pre-conditioning of the layer, chamber saturation, developing distance and final drying can be preset and automatically monitored by the ADC 2. Two modes of operation are possible: stand-alone with input of parameters via keypad, or software-controlled operation with visionCATS, enabling process monitoring, documentation of operating parameters, and reporting.
The fully automated ADC 2 employs a 20 x 10 cm Twin Trough Chamber for development, allowing to retain the chromatographic conditions of already existing analytical procedures while excluding environmental and operational effects.
The option Humidity Control allows reproducible chromatography at defined activity of the layer. This feature is essential in method development when the influence of relative humidity shall be investigated. Operated with visionCATS, the ADC 2 can be used in a cGMP/GLP environment and supports compliance with 21 CFR Part 11.
Key Features
- Fully automated development
- Development in 20 x 10 cm Twin Trough Chamber
- HPTLC plates (20 x 10 cm)
- Operation in stand-alone mode or software-controlled
- Fully traceable operation
- Option Humidity Control allows reproducible chromatography
Detection of chemical warfare agents by HPTLC
Chemical warfare agents pose a significant threat to human health and can cause a range of symptoms from irritation to death. It is important for law enforcement agencies and military personnel to have the knowledge and tools necessary to detect and prevent exposure to these harmful substances. High-Performance Thin-Layer Chromatography (HPTLC) is a reliable and widely used analytical technique for the identification of chemical warfare agents including nerve agents, blistering agents, irritants and arsenic agents. Explore CAMAG's collection of a range of studies where HPTLC is used to identify and quantify a variety of chemical warfare agents, critical in securing the safety of individuals and communities.
Detection of UV filters in cosmetic products (sunscreen) by HPTLC and confirmation by HPTLC-MS
Sunscreen products contain UV filters that absorb or reflect a part of the sun’s ultraviolet (UV) radiation. The identification of UV filters in cream can be a challenging task because of the multiple ingredients used in the cosmetic formulation. After simple sample preparation followed by HPTLC separation, the presence of the target compounds can be confirmed by mass detection.
Ensuring quality and authenticity in mushroom supplements using HPTLC
The functional mushroom extract market is experiencing rapid growth, yet the quality and authenticity of many products remain questionable due to a lack of validated identification methods.
Join Dr. Melanie Broszat, Professor of Analytical Chemistry at Offenburg University of Applied Sciences and Editor of CAMAG’s CBS Journal, and Coleton Windsor, Analytical Chemist at Nammex, a leader in mushroom extract production and quality testing, as they introduce a fit-for-purpose, validated HPTLC method. This new method enhances quality control transparency and reliability by addressing industry concerns over mislabeling and product efficacy, setting new standards for quality testing in mushroom extract markets. Find out how this cutting-edge technique was specifically designed for the accurate identification of multiple fungi species.
Key learning objectives
- Understand the significance of accurate species identification in the mushroom extract food and dietary supplement industries
- Learn how the HPTLC method enhances quality control by differentiating between authentic mushroom and myceliated grain products
- Gain insights into composition and quality differences between commercially available fungi products, as well as the challenges associated with mislabeling
Who should attend?
- Quality control professionals in the dietary supplement and functional food industries.
- Product developers and manufacturers of mushroom-based supplements.
- Regulatory and compliance specialists focused on product authenticity and labeling.
- Researchers and scientists interested in mushroom identification and analysis.
- Industry stakeholders seeking to improve transparency and trust in mushroom products.
Certificate of attendance
All webinar participants can request a certificate of attendance, including a learning outcomes summary, for continuing education purposes
Development of an HPTLC method for evaluating vegetable oil adulteration
Join this webinar to discover how HPTLC can enhance the reliability and efficiency of your edible oil quality assessments.
Dr. Tiên Do, Chief Scientific Officer at CAMAG, and Paul Rogeboz, Junior Research Assistant at Nestlé Research will discuss how a newly developed HPTLC method was developed to identify edible oils. Find out how it was used to detect adulteration with remarkable accuracy.
Our experts will also explore the statistical validation of the method, its robust performance in interlaboratory studies, and its ability to identify adulteration levels from 5% to 25%.
Key topics discussed in this webinar will include:
- Understanding HPTLC for oil authenticity: Gain insights into the principles and applications of high-performance thin-layer chromatography (HPTLC) in ensuring edible oil authenticity
- Method development and validation: Learn about the development of the untargeted fingerprint profiling method for detecting vegetable oil adulteration and the statistical validation processes for variability, detection limits, and reproducibility
- Real-world application and robustness: Discover the robustness of the HPTLC method through interlaboratory studies and understand its practical applications in the food industry
- Detection capabilities: Explore the method's ability to accurately detect adulteration levels ranging from 5% to 25%
Who should attend?
- Quality control professionals
- Food industry researchers
- Regulatory affairs specialists
- R&D teams
- Food manufacturers
- Lab technicians
Certificate of attendance
All webinar participants can request a certificate of attendance, including a learning outcomes summary, for continuing education purposes.
2nd HPTLC Online User Meeting, hosted by the HPTLC Association
Promoting the use of HPTLC in plant analysis and other analytical fields is the main purpose of the International Association for the Advancement of High-Performance Thin-Layer Chromatography (HPTLC Association). For this, we bring together representatives from academia, industry, research, regulatory, and standard setting bodies.The “HPTLC Online User Meetings” shall facilitate a worldwide exchange of knowledge between HPTLC users and share the spirit of working in an exciting analytical field!
Using just classical Silica gel 60? There is more!
The stationary phase most commonly used in basic and High-Performance Thin-Layer Chromatography is the classic Silica gel 60 layer. It is also referred to as the normal phase. However, for many applications the choice of a modified silica gel layer could lead to a much better chromatographic result. Plus, the corresponding mobile phase may permit the use of less hazardous solvents. This session will discuss the diverse properties of available stationary phases, and present unique application examples to illustrate the possible improvements of separation conditions.
How to assess the safety of food products in absence of toxicological data
Assessing the safety of food is challenging as foods are complex mixtures containing thousands of known and unknown substances occurring at various concentrations. What is the best method to detect chemicals of most concern on which further toxicological investigations should be focused? Recent progress using Thin-Layer Chromatography (HPTLC) coupled to bioassays has been proposed as a breakthrough solution to fill some of the gaps identified with standard bioassays. In this session, HPTLC effect-direct analysis (EDA) for toxicologically relevant endpoints will be presented, anchoring bioassays and chemical analysis in complex mixtures of unknown composition with the goal to optimize and speed up decision-making in Food Safety.
Space for discussions – Meet the speakers and representatives from the HPTLC Association in a follow-up meeting held via Zoom at 15:15 BST
Take the opportunity to engage in discussions with speakers, colleagues, and representatives from the HPTLC Association in a moderated Zoom meeting, scheduled immediately after the main event. A separate registration for the Zoom meeting is not required – registrants for the main event will receive an email invitation with an access link one day prior to the event. Additionally, a QR code and a shortlink will be displayed after the Q/A session to bridge the gap, enabling a seamless transition from the webinar platform to the Zoom meeting also for last minute registrants.
Key learning objectives
- Extend your knowledge about HPTLC and understand the benefits of HPTLC for diverse applications.
- Get insights into the daily work of HPTLC users.
- Learn how to optimize your HPTLC application(s).
Who should attend?
- Researchers
- Students
- Analysts
- Technicians
- Scientists
- Members of the HPTLC Association
Certificate of attendance
All webinar participants can request a certificate of attendance, including a learning outcomes summary, for continuing education purposes.
This event is sponsored by:
An introduction into the CAMAG Automatic Developing Chamber 2 (ADC 2)
In this video, CAMAG introduces the ADC 2, an automating developing chamber that offers convenience, safety, and reproducibility for isocratic developments of 20 x 10 cm HPTLC glass plates.
