Products & ReviewLife Sciences

Accel-Amplicon™ 56G Oncology Panel v2 (48 reactions)

Swift Biosciences, IncAL-56048Available: Worldwide

Multiplex amplicon panels for Illumina® platform.

Swift Biosciences, Inc

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Description

All-in-one amplicon solution.

Offers comprehensive and hotspot coverage of 56 clinically-relevant oncology-related genes, using a 263-amplicon design to generate multiplex libraries compatible with Illumina sequencing platforms. This product is a complete kit that includes all elements necessary for generating ready-to-sequence libraries, including primer pairs and indexed sequencing adapters.

Benefits include:

  • Single-tube assay.
  • Ready-to-sequence libraries in 2 hours.
  • Inputs as low as 10 ng.
  • Average amplicon size of 138 bp for compatibility with cfDNA and FFPE.
  • Limit of detection as low as 1%.
  • On-target specificity and coverage uniformity > 95%.
  • Leverages the high fidelity performance of the Illumina platform.
  • Complete library generation in a single kit.
Application NoteLife Sciences

Accel-Amplicon™ Panels

The publication describes the range of Accel-Amplicon™ Panels offered by Swift Biosciences. The panels are highly adaptable, and are especially applicable for in-depth interrogation of numerous oncology-related targets in a single run. It also highlights a publication featuring a single-tube, 2-hour workflow, using an Accel-Amplicon Panel.


Scientific PosterLife Sciences

Detecting Cancer Burden in Liquid Biopsies

Liquid biopsy is a non-invasive sample source that can be utilized to assess cancer burden by measuring the tumor-derived fraction of circulating, cell-free DNA (cfDNA) from plasma. The study detailed on this poster evaluates two methods to monitor cancer burden using cfDNA: whole genome bisulfite sequencing (WGBS) and targeted amplicon sequencing for 56 oncology-related genes.


Application NoteLife Sciences

A Guide to NGS Applications Using cfDNA Samples

This guide from Swift Biosciences provides an introduction to using cell-free DNA to construct NGS libraries for use in cancer research. The guide compares the range of kits available, how well they perform and their limitations.

Mutation Profiling of Uterine Lavage Fluid: Detection of Early Stage Endometrial Cancers

This presentation, given at AMP 2016 by John Martignetti, MD, PhD, from the Laboratory of Translational Research, The Mount Sinai Hospital, discusses the development of a tool for the early detection of endometrial cancers. John Martignetti describes his research into developing the established Molecular Signature Method (MSM) into a diagnostic tool. The presentation covers the theory behind the method, results from a prospective study and the future directions of the research.

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