SmartFlare™ RNA Detection Probes A Breakthrough Solution Enabling Gene Expression Analysis and Live Cell Sorting
22 Mar 2013Get a first-hand introduction to EMD Millipore's groundbreaking SmartFlare™ RNA Detection Probes at AACR. SmartFlare™ RNA Detection Probes, allow the detection of RNA expression in live, intact cells with only a single incubation step.
This novel reagent technology allows researchers to detect gene expression in live, intact cells - overcoming the limitations of lysed or fixed cell populations and yielding more physiologically relevant information. The probes eliminate laborious sample preparation while offering the new ability to track changes in RNA over time, allowing researchers to explore more meaningful links between genotype and phenotype.
SmartFlare™ RNA detection probes offer:
• Identification of cell types and cell sorting based on RNA expression levels without transfection reagents or intrusive sample preparation
• A single incubation step using inert nanoparticle technology to specifically detect native RNA
• Ability to use the same cells in downstream assays
EMD Millipore will be introducing the SmartFlare™ probes in the Exhibitor Spotlight Theater on Tuesday, April 9 at 12:30 PM, as well as giving seminars on RNA and miRNA expression in booth #538 at various times Sunday, April 7 through Wednesday, April 10.
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SmartFlare RNA Detection Probes
MerckSmartFlare Probes work by recognizing specific native RNA sequences within living cells, therefore there are many possible sequences that you could design to recognize your target of interest. Instead of lysed cells, switch to live cells. And while you’re at it, eliminate sample preparation and transfection steps all together. Live cell RNA detection is now possible, in a single incubation step using inert nanoparticle technology to specifically detect native RNA. And when you’re done, the probes exit the cells allowing you to perform downstream analyses with the same, unperturbed cells. Make the smart change!SmartFlare RNA Detection Probes are fueled by the NanoFlare technology developed by renowned chemist Dr. Chad Mirkin.What's Smart? Detect RNA expression in live cells for real time, physiologically relevant data Eliminate laborious, costly sample preparation Easy analysis on the fluorescent detection platform of your choice Nanoparticle based technology that allows cells to be used for downstream assays