Product News: Discover KNAUER AZURA UHPLC Systems

For when your analytical task requires more than standard HPLC resolution, sensitivity or throughput

15 Apr 2016

AZURA® UHPLC systems provide an extended backpressure range of 1000 bar and an optimized dwell volume. These liquid chromatography systems are made for demanding separation tasks and high throughput applications. Choose between a 2 x 2 solvent binary high pressure gradient (HPG) and a quaternary low pressure gradient (LPG) pump to configure the UHPLC system ideal for your application.

UHPLC eluent supply

AZURA UHPLC pumps feature a maximum backpressure of 1000 bar up to 2 ml/min with a maximum flow rate of 5 ml/min at 700 bar. With a 50 µl high efficiency mixer and fine capillary tubing, AZURA UHPLC pumps achieve excellent gradient reaction time. High precision flow with compressibility compensation, automatic piston back flushing for longer seal life, integrated degasser for a good signal-to-noise ratio, changeable pump filter and leak management are standard features.

Sampling and column temperature

Inject up to 96 samples from vials or up to 768 samples from microtiter plates. This highly precise UHPLC autosampler features 0.1 µl sample aspiration and an efficient wash procedure for low carryover. The air-flow column thermostat AZURA CT 2.1 keeps the temperature stable for reproducible results. It can accommodate up to 6 analytical columns.

Diode array detection

A UHPLC system also puts high demands on detection. The new AZURA Detector DAD 6.1L with its LightGuide technology flow cells offers very high sensitivity with an extremely low dispersion volume. The LightGuide 50 mm flow cell features a delay volume of just 2 µl. This combination of a long light path with a minimal cell volume enables highly sensitive detection of even very narrow peaks. Frontal access and improved safety features enable effortless lamp replacement for easy maintenance and short downtimes.

Control flexibilty

Every AZURA UHPLC system can be controlled by OpenLab® EZChrom or ClarityChrom®/Clarity® software. Drivers for Chromeleon® are also offered. Furthermore, the KNAUER Mobile Control app for Windows® 8 or higher is available for each system. It runs on tablet or PC.

Key features

  • High precision eluent supply up to 1000 bar
  • 2 x 2 HPG or 4 x 1 LPG gradient UHPLC pump
  • High efficiency mixer
  • Autosampler with 0.1 μl sample aspiration
  • Max. 768 samples
  • Sensitive diode array detector
  • Wavelength range 190 – 1000 nm
  • 8 detection channels (digital), 4 (analog)
  • User-friendly and easy maintenance


Key applications

  • High sensitivity analysis
  • UHPLC separations of complex mixtures requiring high resolution
  • High throughput analytical tasks, many samples in succession