Reference Materials/Research Services

LGC is highly experienced in the application of a broad range of material characterisation techniques and packages and has the knowledge to support your product development from discovery to product registration and beyond. Read more...

Bringing together Axolabs, Biosearch Technologies and the broader analytical and bioanalytical capabilities available across the company, LGC has a unique heritage and expertise in the development oligonucleotide therapeutics and nucleic ... Read more...

Mosaic gives you full control of your samples. It manages their storage and processing throughout their lifetime. The push to accelerate drug discovery places significant strains on the sample bank. Libraries are growing. Throughputs ... Read more...

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ProBioGen holds a manufacturing authorization for GMP (Good manufacturing practice) compliant manufacturing and batch release of biotechnological drug substances and fulfills all present regulatory requirements by EMA and FDA. GMP Man... Read more...

Stable, High-Yield Mammalian Producer Cell Lines. ProBioGen's in-house cell line engineering platform enables them to provide our clients with pharmaceutical producer clones that exceed the limits of the current industrial standa... Read more...

ÄKTAcrossflow™ is a fully automated filtration system for cross flow filter screening, process development and small scale processing. The GE Healthcare’s AKTAcrossflow enables automation at very small scale, with capacity ranging from l... Read more...

In the fast growing Biopharma market, the need for ultra clean sterile packaging is growing at a high speed, often driven by regulatory authorities and cGMP regulations. Eliminating every risk of delivering a contaminated parenteral d... Read more...

Powerful molecular design and 3D SAR analysis for medicinal chemists Torch is a powerful design and 3D structure activity relationship (SAR) software workbench. Medicinal chemists use Torch to design the next compound for synthesis or... Read more...

Forge is a powerful computational chemistry suite for understanding SAR and design. Forge gives you control and insight into your activity data enabling you to plan the direction of your project with confidence. Using the shape and el... Read more...

SAR analysis is an expert field, which is why many customers prefer an outsourced solution. Our scientists use a variety of techniques to study SAR. These range from simple ligand alignment to more involved methods such as 3D QSAR, qu... Read more...

Libraries of chemical compounds are the lifeblood of modern pharmaceutical discovery programs. The quality of library design can determine a project’s success or failure. Both molecular modeling and cheminformatics techniques are impo... Read more...

CAS SciFinder -  The First Choice With SciFinder from CAS, you can increase your productivity and achieve faster breakthroughs Advancing the pace of research, Chemical Abstracts SciFinder search allows you to get results fast withou... Read more...

STN is an online database service that provides global access to published research, journal literature, patents, structures, sequences, properties, and other data.  Read more...

A mutation occurred in a colony of outbred Zucker rats in the laboratory of Dr. Walter Shaw at Eli Lilly Research Laboratories in Indianapolis, IN in 1974–75. Part of this colony containing the mutation was moved to Indiana University... Read more...

Developed by Dr. Lewis from Wistar stock in the early 1950s. To Charles River from Tulane in 1970 at F34. Model Properties: Coat Color: White (albino) MHC Haplotype: RT1  Ideal For: transplantation research, induced ... Read more...

The Spontaneously Hypertensive Stroke Prone Rat (SHRSP)was isolated from Wistar-Kyoto rats by Okamoto and Aoki in 1963. The A3 subline was transferred to the National Institutes of Health in 1975 from Yamori at generation F36. To Charles R... Read more...

Developed from a line of Crl:CD(SD) rats. Two lines were developed from this outbred colony, the OP-CD (Obese Prone) and OR-CD (Obese Resistant). This model becomes obese when fed high-fat diets. Obesity develops despite having a fully fun... Read more...

PCSK9 mice were created utilizing a full-length human PSK9 cDNA with a C-terminal V5 tag expressed under the transcriptional control of a composite human albumin promoter containing a 235 bp SV40 enhancer and a 213 bp albumin promoter ele... Read more...

Okamoto, Kyoto School of Medicine, 1963, from outbred Wistar Kyoto male with marked elevation of blood pressure mated to female with slightly elevated blood pressure. Brother x sister mating with continued selection for spontaneous hy... Read more...

As study protocols become more complex, so too does the need to have an in vivo model that specifically fits your study design. Charles River offers customized animal preconditioning that is tailored to your research requirements. Whe... Read more...

Developed by C.C. Little in 1921, from a mating of Miss Abby Lathrop’s stock that also gave rise to strains C57BR and C57L. Strains 6 and 10 separated about 1937. To The Jackson Laboratory in 1948 from Hall. To NIH in 1951 from The Ja... Read more...

The 11BHSD2 mouse was produced by injection of a construct, containing 11β-HSD2 cDNA isolated from mouse kidney and cloned into plasmid Clone 26 to recruit the 5.4 kb mouse α–myosin heavy chain (α-MHC) promoter, into pronuclei of C57BL/6 e... Read more...

Developed by C.C. Little in 1921, from a mating of Miss Abby Lathrop’s stock that also gave rise to strains C57BR and C57L. Strains 6 and 10 separated about 1937. To Hall in 1948 from The Jackson Laboratory. To NIH in 1951 from The Jackson... Read more...

Silvers and Billingham began brother x sister matings with selection for histocompatibility in 1958 from a brown mutation in a stock of wild rats maintained by King and Aptekman in a pen-bred colony of rats trapped from the wild in 1930 by... Read more...