SelectScience
Join Free
NewsLife Sciences

The tech used by cell and gene therapy scientists

SelectScience

Find out which lab products scientists are using to advance the field and what their experiences have been

27 Mar 2024
Ellen Simms
Product and Reviews Editor

Editorial article

Insights into lab equipment and services other scientists are using can be invaluable. The independent reviews on SelectScience® are there to help guide and support your own research and give you a platform to share your expert opinions.

In our Accelerating Science Cell and Gene Therapy Feature, we are exploring some of the latest developments within the field. Here, we highlight top reviews from our community on the key technology and techniques that are relevant to your workflows. From gene editing to manufacturing, discover what applications researchers use these products for and the benefits they have encountered.

NucleoCounter® NC-200™ automated cell counter by ChemoMetec

Application area: Cell therapy products (manufacture and quality control).

Reviewer: Andreas Mitsch, Leibniz-Institut für Immuntherapie.

“We replaced our manual cell counting procedure by NC-200 for in-process and final product controls of ATMP manufacture. High increase in reproducibility and reduction of analysis time greatly supported optimization of cell therapy manufacturing process.”

Read more reviews Leave a review NovoCyte Flow Cytometer by Agilent Technologies

Application area: Immunoassays.

Reviewer: Lei Zhang, CytoImmune Therapeutics

“As an R&D scientist in the cell therapy field, I need to perform vast amounts of immunoassays. The NovoCyte Benchtop Flow Cytometer from Agilent Technologies is a lifesaver with high-throughput and reliable reproducibility! In addition to the very user-friendly equipment application, I am always impressed by their Craftsman’s SPIRIT and pre/post services!”

Read more reviews Leave a review Clonal Genes by TWIST Bioscience

Application area: Cloning complex cell therapy constructs for transduction.

Reviewer: Andrew Lezia, Port Therapeutics

"Twist is the fastest and cheapest DNA synthesis service I’ve used. In addition to their excellent product, they have really good customer support. Their website has an instant messaging portal where you can very quickly speak to a real person within minutes. This helped me when there was a shipping delay for my order. Overall, I give twist my highest seal of approval."

Read more reviews Leave a review SeqStudio™ Flex Genetic Analyzers by Thermo Fisher Scientific

Application area: Sanger Sequencing.

Reviewer: Sanny Khurdia, Concordia University

“We never imagined that bringing Sanger sequencing in-house would simplify our research workflow – and we are saving more than half our costs per run! If you can afford the initial capital expense – this instrument is very much worth it.”

"This has revolutionized our lab."

Read more reviews Leave a review ZR DNA Sequencing Clean-up Kit™ by Zymo Research

Application area: DNA clean-up before Sanger sequencing.

Reviewer: Brett Sansbury, Gene Editing Institute

“This product was a game changer for our sequencing workflow, it reduced the time needed for DNA clean-up prior to Sanger sequencing by 40 minutes, increased the sequencing quality and the reusable format drastically reduces the cost per clean-up.”

Read more reviews Leave a review MiSeq Personal Sequencer by Illumina

Application area: Targeted genomic sequencing to study clonal dynamics in cancers.

Reviewer: Damian Yap, University of British Columbia

"We were able to very quickly set up and run a targeted sequencing pipeline to study the clonal dynamics of many human tumors and their models (patient-derived xenografts) in vivo."

Learn more Leave a review

Your knowledge helps other scientists   Your expert opinions on the scientific equipment, products or services in your lab can help other scientists identify the right products to accelerate scientific progress, and that benefits us all. Do you work in cell and gene therapy research and development? Leave a review today.
Leave a review

Links

SelectScienceCompany website

Tags

Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.DNA SequencingDNA sequencing, such as sanger sequencing, is a biological technique that determines the precise order of nucleotide bases in a fragment or template of DNA. DNA sequencers and genetic analyzers are based on capillary electrophoresis, where labeled DNA fragments are electrophoretically separated by size as they migrate through a polymer. Find the best DNA sequencing products, including DNA sequencing kits, genomic libraries and genetic identity kits in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Next Generation SequencingNext-generation sequencing (NGS), also known as whole-genome sequencing, high-throughput sequencing and massive parallel sequencing, produces and analyses thousands to millions of nucleotide sequences at once. Sequencing systems operate via varying technologies depending on the manufacturer, including sequencing by synthesis, ligation, pyrosequencing, ion semiconductor and single-molecule real-time sequencing. For NGS, library preparation is paramount to successful sequencing. In this section, explore a range of library preparation kits, from targeted, amplicon-based or hybridization-based kits including epigenomic, transcriptomic and genomic workflows to fragmentation kits. Find the best next-generation sequencing products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.ImmunoassayImmunoassays are laboratory tests that utilize antibody-antigen interactions to detect specific substances. They are widely used in diagnostics for detecting diseases, drug testing, and environmental monitoring. These assays offer rapid, sensitive, and precise detection of biomarkers, making them invaluable in clinical and research labs. Browse our peer-reviewed product directory to compare immunoassay systems, read user reviews, and get pricing directly from manufacturers.DNADeoxyribonucleic Acid (DNA) is the main component of chromosomes and the carrier of genetic information of living organisms. Find out here about PCR, NGS, ChIP-Seq, gel imaging, and many other techniques which can be used for the analysis of DNA.Cell TherapyCell therapy involves using living cells to treat diseases, often by replacing damaged cells or stimulating regeneration. Stem cell therapy and CAR-T cell therapy are examples of cutting-edge treatments in regenerative medicine and cancer immunotherapy. Browse our peer-reviewed product directory to find the best cell therapy tools, compare products, check reviews, and get pricing directly from manufacturers.SequencingSequencing refers to determining the order of nucleotides in a DNA or RNA molecule. This process is essential in genomics, diagnostics, and evolutionary biology. Techniques like next-generation sequencing (NGS) and Sanger sequencing provide high-throughput and precise data for analyzing genomes and transcriptomes. Browse our peer-reviewed product directory to find the best sequencing tools and reagents, compare products, check reviews, and get pricing directly from manufacturers.Genome SequencingGenome sequencing involves determining the complete DNA sequence of an organism's genome. It provides crucial information about genetic variations, mutations, and diseases. Advances in sequencing technologies, such as next-generation sequencing (NGS), have accelerated research in genomics, diagnostics, and personalized medicine. Explore genome sequencing tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Gene TherapyGene therapy is a technique that modifies or replaces genes within an individual's cells to treat or prevent diseases. This approach holds potential for curing genetic disorders, cancers, and certain viral infections. Advances in gene editing technologies like CRISPR are driving the growth of gene therapy. Explore gene therapy tools and technologies in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.

Related articles