Waters breakthroughs and clinical laboratory solutions provide an enduring platform for customer success

24 Jun 2007

Product news

Waters Corporation creates business advantages for clinical organizations by delivering practical and sustainable innovations to enable significant advancements in areas such as therapeutic drug monitoring, forensic and drugs of abuse worldwide.

Visit us at booth #2222 to register for our Industry Workshop "LC/MS/MS for Immunosuppressants Accurate Measurement and Monitoring" and learn more about Waters' portfolio of separations science, ChromaLynx™ application manager and mass spectrometry.

ChromaLynx Application Manager

Waters

The ChromaLynx™ Application Manager automates the processing of LC/MS or GC/MS and LC/MS/MS or GC/MS/MS data. While the high chromatographic separation efficiency and narrow peak widths typical of GC/MS often increase the challenge to identify co-eluting components, ChromaLynx facilitates the rapid detection, identification and semi-quantitative determination of all components. Manually reviewing complex chromatograms to locate potentially significant components is a laborious, time-consuming and subsequently expensive task that is often only partially successful; some closely eluting components are often missed. Meanwhile, the need to qualitatively and semi-quantitatively analyze complex mixtures is encountered in many industries. From the development and QC of flavor and fragrance compounds, to the study of plant metabolism to identify the effects of genetic modification, there are many common requirements that are addressed by ChromaLynx: Detect and locate the maximum number of components in the sample Identify of the maximum number of components in the sample Estimate component concentrations Compare of samples to controls to identify common and unique components

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UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.