VersaMatrix A/S launches Versaffin™ for affinity resin-mediated bioseparation

27 Jun 2006

Product news

VersaMatrix A/S today announced the global launch of Versaffin™, the Company’s proprietary bead-encoding technology to produce Customized Affinity Ligands – small molecules that can selectively bind and release desired proteins and other biomolecules.

Ligands derived using Versaffin™ provide superior performance in affinity chromatography for the purification of biopharmaceutical drugs.

The production of biopharmaceutical products can be a costly process, with 50-80% of the cost being accrued in down stream purification processes. And with tight time constraints, a rapid means of developing purification processes is essential. Affinity chromatography has been known for some time to be one of the most effective methods of protein purification but has historically been problematic because of insufficient access to selective, robust, high affinity ligands. VersaMatrix has developed Versaffin™ to solve this problem by ensuring the fast, and thereby cost-effective, development of Customized Affinity Ligands. The technology provides information on relative binding and elution of target proteins to all members of large libraries of ligands. Using this approach, companies can save between 15 and 20% on production costs.

Ib Johannsen, VersaMatrix’ CEO commented:

“Versaffin™ ensures that affinity ligands can be developed in a matter of weeks instead of months. This time reduction translates into cost savings for cash strapped biopharmaceutical companies moving into protein production. We are confident that our technology will help the industry boost its profits from biopharmaceuticals!”

The scientific basis of Versaffin™ was originally developed at the Carlsberg Research Centre in Copenhagen. VersaMatrix was founded in September 2002 to commercialise the research and the result is the Versaffin™ bead-encoding technology. VersaMatrix is wholly owned by Carlsberg A/S.

Links

Tags

ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.Protein PurificationProtein purification is a vital step in drug discovery, therapeutics, biotech and life science research. The purification process typically involves subcellular or membrane protein extraction with cell lysis kits, separation of proteins from cell debris by filtration or spin columns, and the isolation of proteins of interest from other proteins and impurities with affinity purification (including fusion protein tags and antibody binding proteins A, G and L), immunoprecipitation or chromatographic methods, such as ion exchange, size exclusion and immobilized metal affinity chromatography. All purification methods come in multiple formats for your laboratory needs, including agarose or magnetic beads, resins, columns and filter plates. Find the best protein purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.
VersaMatrix A/S launches Versaffin™ for affinity resin-mediated bioseparation