Tosoh Bioscience announces partnership to improve the purification of viruses

This research project promises to reduce the costs of cell and gene therapy manufacturing processes, making therapies more accessible and cost-effective

13 Jun 2024

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Tosoh Bioscience, a leading provider of chromatographic solutions for biomolecule separation and purification, has announced a pioneering partnership with Prof. Dr. Michael Wolff from the University of Applied Sciences Mittelhessen (THM), Gießen, Germany, which will focus on developing continuous purification processes for viruses and viral vectors. This collaboration aligns with Tosoh Bioscience’s efforts to support the cell and gene therapy (CGT) industry and researchers worldwide.

Advancing CGT purification technologies

The goal of this partnership is to improve the purification process of viruses, using Modified Vaccinia virus Ankara (MVA) and Orf viruses as model viruses, as well as adeno-associated virus (AAV) particles. This research project promises to reduce the costs of CGT manufacturing processes, making therapies more accessible and cost-effective. Dr. Carsten-René Arlt, Application Scientist at Tosoh Bioscience, will also support the project with his bioprocess technology expertise.

Prof. Dr. Michael Wolff, commented, "The partnership with Tosoh Bioscience represents a fantastic opportunity to push the boundaries of bioprocessing technology. Together, we aspire to develop a more efficient, continuous chromatographic method for virus and viral vector purification that could greatly enhance the economic viability of CGT manufacturing processes."

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Bioprocessing / FermentationBioprocessing is the use of biological materials to perform commercial, scientific or medical research processes. Biological materials used include cells, enzymes and organisms. Usually bioprocessing requires a batch or continuous bioreactor such as a fermentor or cell culture system. The advantages of using a reactor include high productivity, easy configuration, adjustable values and automation.ChromatographyChromatography is a powerful technique used to separate and analyze components of mixtures based on their chemical properties. It is widely used in fields like biochemistry, pharmaceuticals, and environmental analysis. By exploiting differences in the interaction of substances with a stationary phase and a mobile phase, chromatography enables precise purification and quantification of compounds. Whether you're working with complex biological samples or industrial chemicals, chromatography is essential for obtaining high-quality results. Browse our peer-reviewed product directory to find the best chromatography systems, compare products, read customer reviews, and get pricing directly from manufacturers.VirusesViruses are microscopic pathogens that require a host cell to replicate. Understanding their structure, replication cycle, and impact on the immune system is crucial in developing effective treatments, vaccines, and diagnostic methods. Research continues to focus on emerging viral diseases and antiviral drug discovery. Explore solutions for virus research, detection, and treatment in our peer-reviewed product directory; compare products, check customer reviews, and get pricing directly from manufacturers.Purification SolutionsViral Vectors
Tosoh Bioscience announces partnership to improve the purification of viruses