Top Cancer Researchers to Showcase Performance Data at AACR Annual Meeting

8 Apr 2014
Sarah Thomas
Associate Editor

RainDance Technologies, Inc., a genomics tools company simplifying the analysis of complex genetics, has announced the availability of its ThunderBolts™ Cancer Panel, a comprehensive next-generation DNA sequencing (NGS)solution that enables researchers to profile a wide range of tumor samples in fewer than two days for as low as $100 per sample. During this week’s American Association for Cancer Research (AACR) Annual Meeting, several prominent cancer researchers and collaborators in RainDance’s First Access Program (FAP) will present their latest findings demonstrating the product’s high sensitivity, low starting sample requirements and simple workflow in breast, colorectal, esophageal, and pancreatic cancer studies. These leading researchers will share their data and experience using the ThunderBolts Cancer Panel for profiling tumor samples and the RainDrop Digital™ PCR System for follow-up mutation validation.

“With the launch of the ThunderBolts Cancer Panel, RainDance now has a portfolio of research products aimed at elucidating genetic targets for cancer risk predisposition, initial detection, pathology and residual disease,” said Roopom Banerjee, President and CEO of RainDance. “We have assembled an exciting group of thought leaders who are demonstrating what is possible by unlocking genomic information hidden in millions of biopsies and biobanks. Moving forward, this type of research will not only change the way cancer is understood, but ultimately, how it is detected and monitored.”

ThunderBolts Cancer Panel Advantages
The ThunderBolts Cancer Panel targets 50 important and well known cancer genes, including the content found on the Ion Torrent AmpliSeq™ Cancer Hotspot Panel v2 and Illumina TruSeq® Amplicon Cancer Panel products. The panel features a fast, simple workflow that is optimized for Illumina NGS systems and compatible with FFPE samples with as low as 10 ng of starting DNA. The panel runs on the same compact $50,000 RainDrop Source Instrument and consumables as the RainDrop Digital PCR System. Researchers gain rapid, accurate cancer mutation profiles for as low as $100 per sample.

RainDrop™ Digital PCR System

RainDance Technologies, Inc.

A Billion Reactions. Digital Answers. Experience the Next Generation of PCR. Capable of generating more than a billion reactions in a single day, the RainDrop™ Digital PCR System surpasses all existing technologies and establishes a new performance standard in sensitivity, quantitation, and multiplexing.Based on RainDance’s proven picodroplet platform, the RainDrop System delivers absolute quantitation of target molecules. The RainDrop Digital PCR System fundamentally changes the performance of molecular assays by enabling digital answers across a number of important applications including low-frequency tumor allele detection, absolute quantitation of expression profiles or DNA copy numbers, and SNP measurement.A new gold standard in sensitivity is only possible through the careful consideration of every aspect of the system. The RainDrop System offers a number of innovative droplet-based design advantages.RainDrop™ Digital PCR System Features & Benefits: Superior Sensitivity - Detect 1 mutant amongst 250,000 wild-type molecules with a lower limit of detection of 1 in more than 1,000,000. Unprecedented Multiplexing - Conduct up to 10 tests or more on the same sample using the single molecule multi-color detection technique. Greater Study Design Flexibility - Optimize the number of PCR reactions based on your sensitivity AND multiplex requirements. Closed-Tube Design - Ensure the highest quality data by eliminating contamination or carryover Proven Picodroplet Platform - Leverage a decade of experience with the same technology found in RainDance’s Targeted Sequencing Systems. Lowest Cost per Data Point - Generate true digital answers with orders of magnitude more data per dollar.

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