Thermo Fisher Scientific to Demonstrate Software for Simplified Bioanalytical Workflows at ASMS 2010

17 May 2010
Sarah Sarah
Marketing / Sales

Thermo Fisher Scientific Inc. will be demonstrating the TSQ Module™ software for the Watson™ laboratory information management system (LIMS). This industry-first integration of LIMS and instrument control software coupled to the Thermo Scientific TSQ Series triple quadrupole mass spectrometer significantly increases efficiency by enabling data from the entire bioanalytical workflow to reside in a single database.

The combination also provides increased regulatory control by managing the workflow from beginning to end with data review, processing, reporting and archiving all under the control of Thermo Scientific Watson LIMS. A new five-minute video demonstration is now available to view by following the Company article page link top right of this page.

The TSQ Module software works with Watson LIMS and TSQ Series mass spectrometers to enable direct LC/MS data acquisition. Where companies are operating TSQ Series mass spectrometers in multiple laboratories worldwide, worklists created in Watson LIMS can be directly submitted to the instrument over the network via the TSQ module. This functionality allows laboratory managers to balance workloads among multiple resources globally. The user friendly software offers seamless data processing, enabling easier sample tracking and management while providing Watson users with the ability to review in-process and completed samples. This LIMS and instrument control software combination provides confidence in data security throughout the entire bioanalytical workflow from method development to data archiving while built-in data interchange enables peak integration and re-integration, storage, archiving and reporting of raw data all under control of Watson LIMS for enhanced security. Connectivity between the LIMS and the TSQ Series mass spectrometers also eliminates time-consuming file transfers and manual verification of data and provides a single audit trail for QA and FDA requirements, resulting in improved workflow efficiencies as well as time and cost savings.

The video demo will enable laboratory directors, managers and executives in Good Laboratory Practice (GLP) laboratories within pharmaceutical companies and CROs to understand how the efficiency of their everyday workflows can be improved by integrating LIMS and mass spectrometry hardware in the bioanalytical laboratory. An in-depth introduction to the software is provided and customers are guided virtually through the TSQ Module’s simple intuitive interface for acquiring data and managing runs. Key capabilities of this powerful combination are emphasized including the ability to select which runs to acquire on the TSQ Series and using the interactive environment to review the run list. Also demonstrated is the solution’s flexibility to assign priority status to runs as well as the benefits of being able to directly perform data processing in Watson LIMS.

Jonathan McNally, manager, bioanalytical-GLP at Thermo Fisher Scientific, comments: “This video demo enables customers to understand the strength of this end-to-end solution for improving laboratory workflows. Users will be able to see the benefits of allowing LIMS to control the entire bioanalytical workflow enabling all study information to be stored in a single database that can be accessed from one software environment where security and functionality are easily managed.”

For more information visit booth 69.

Finnigan TSQ Quantum Series

Thermo Fisher Scientific

The Finnigan TSQ Quantum Series of mass spectrometers are the most advanced and powerful triple quadrupole mass spectrometers available. The Quantum Series mass spectrometers feature the patented HyperQuad™ mass analyzer technology, a rugged orthogonal source, and a completely redesigned analyzer geometry for maximum sensitivity, precision, and reliability. The Quantum Series triple quads are the only commercial triple quads available today capable of performing H-SRM. Thanks to H-SRM, co-eluters with nominal masses that vary by 0.1 amu are no longer interfering ions. Product detail: The NEW Finnigan TSQ Quantum Discovery MAX: Extraordinary Value The high-performance, ultra compact benchtop Finnigan TSQ Quantum Discovery MAX incorporates innovative new technology for increased sensitivity, precision, ruggedness, and reliability. It is principally designed for high-productivity environments such as environmental, clinical and drug discovery laboratories. With the Ion Max source, the Finnigan TSQ Quantum Discovery MAX addresses the need of these laboratories for more rugged and dependable LC/MS/MS to enable around-the-clock productivity. The combination of our patented HyperQuad™ mass analyzer system, high efficiency ion transfer optics, and outstanding ion source roboustness provides precise accurate quantitation even at the lowest levels. The Finnigan TSQ Quantum Ultra EMR™: Peerless Versatility Thermo introduces the newest addition to its Finnigan TSQ Quantum Ultra series of triple quadrupole mass spectrometers, already established and recognized for its standard of excellence in mass spectral quantitation. The Finnigan TSQ Quantum Ultra EMR™ offers higher resolution and an Extended Mass Range of up to 3000 Daltons. This extended mass range capability allows high-resolution analysis of a whole new class of biopolymers including peptides, polysaccharides, and oligonucleotides. It combines all the benefits of the Finnigan TSQ Quantum Ultra, including constant neutral loss, parent scanning, high-resolution precursor ion selectivity, and Selected Reaction Monitoring, to deliver a complete solution for the proteomics and large molecule research community. The Finnigan TSQ Quantum Ultra™: Definitive Performance The Finnigan TSQ Quantum Ultra defines a new standard of excellence in bioanalytical and environmental analysis.  It features the revolutionary Ion Max source with interchangeable ESI and APCI probes and a wide aperture titanium skimmer for increased robustness and sensitivity. Its large volume ion transfer tube provides enhanced ion transmission, resulting in increased sensitivity. The Ion Max source allows probe adjustment in the x, y, and z directions, for optimum sensitivity and robustness. The Finnigan TSQ Quantum Ultra’s new, ultra-high temperature APCI probe with ceramic heater technology, virtually eliminates sample carryover. Its innovative technology provides the widest linear dynamic range and highest sensitivity of any triple quadrupole mass spectrometer. The Finnigan TSQ Quantum Ultra AM™: Unrivaled Capabilities The Finnigan TSQ Quantum Ultra AM has the additional capability of routine accurate mass measurement on the chromatographic timescale, to facilitate compound identification. It contains a meticulously redesigned analyzer control board, which takes full advantage of the HyperQuads™, and permits accurate mass measurements to within ±5 ppm. This innovation imparts accurate mass measurement performance that is easier to use and have a greater dynamic range than those of instruments based on hybrid quadrupole/time-of-flight technology.

(13)

Tags

Thermo Fisher Scientific to Demonstrate Software for Simplified Bioanalytical Workflows at ASMS 2010