Thermo Fisher Scientific launches Applied Biosystems PowerFlex Thermal Cycler

A next-generation PCR system designed to help labs manage increasing workflow complexity with greater flexibility, speed and confidence in reproducible results

30 Apr 2026

Product news

Applied Biosystems™ PowerFlex™ Thermal Cycler

Applied Biosystems™ PowerFlex™ Thermal Cycler

Thermo Fisher Scientific Inc. has launched the Applied Biosystems™ PowerFlex™ Thermal Cycler, a next-generation polymerase chain reaction (PCR) instrument designed to help deliver enhanced flexibility, precise thermal performance and improved productivity for modern molecular biology laboratories.

Building on the legacy of Applied Biosystems™ instruments, this solution is designed to help laboratories run complex PCR workflows with greater confidence and efficiency.

PCR remains a foundational technique across life science research, applied testing and DNA identification. As labs face increasing pressure to generate accurate results faster, often while sharing instruments across teams, there is growing demand for thermal cyclers that combine performance, adaptability and ease of use in a reliable platform.

Featuring Thermo Fisher Scientific's latest block technology, the PowerFlex Thermal Cycler was developed to help address these evolving needs.

Key benefits include:

  • Fast, precise thermal performance: With advanced thermal technology engineered for speed and precision, the system helps laboratories shorten run times while maintaining the accuracy and reproducibility researchers depend on. Its optimized performance supports confidence across routine and complex PCR workflows alike.
  • Intuitive operation: A large 10.1-inch touchscreen and user-friendly interface make protocol setup and instrument navigation straightforward. Built-in simulation capabilities and AI-assisted Smart Help features guide users through setup and troubleshooting, helping reduce training time and minimize workflow disruptions.
  • Flexible configurations: The PowerFlex Thermal Cycler is available in two models to accommodate different throughput and workflow requirements. A 96-well configuration provides broad plate compatibility to integrate easily into existing lab environments. For labs running multiple assays, the 3x32-well configuration features independently controlled VeriFlex™ blocks, enabling different protocols to run simultaneously on a single instrument and helping maximize bench space and efficiency.

The PowerFlex Thermal Cycler is intended for use across a wide range of applications, including life science research, large academic and core laboratories, biotechnology and pharmaceutical research, food and environmental testing and human identification workflows. The platform is also designed to support future expansion and evolving lab needs.

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PCR and Thermal CyclingPolymerase chain reaction (PCR) kits and thermal cyclers are used for the in vitro amplification of DNA permitting subsequent analysis and experimental procedures. Explore a range of high-quality polymerase, primers and nucleotides or simplify your workflow with a PCR mastermix. Find reverse transcription PCR (RT-PCR) and cDNA synthesis kits for RNA products and libraries. Quantitatively measure the amplification of DNA with real-time PCR (qPCR) and droplet digital PCR (ddPCR) kits and systems, and discover automated PCR setup solutions to increase throughput. Alternative DNA amplification methods also include recombinase polymerase amplification (RPA) kits. Find the best PCR kits and thermal cyclers and purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.DNA AmplificationDNA Amplification is a technique used to amplify a single or multiple copies of DNA or mRNA by orders of magnitude. The most common method employed is PCR, but other options exist that eliminate the need for thermocycling.Molecular BiologyMolecular biology is the branch of biology that focuses on the molecular mechanisms that underlie cellular functions. It involves studying DNA, RNA, and proteins to understand gene expression, replication, and regulation. Molecular biology is fundamental to biotechnology, medicine, and genetic research. Explore molecular biology products in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.