Symyx Technologies Releases New Version of Symyx Software Discovery Notebook

10 Jan 2007

Product news

Symyx Technologies, Inc. today announced the release of Symyx Software Discovery Notebook version 4.0. Using the Symyx Discovery Notebook, chemists in pharmaceutical discovery research can plan, record and analyze research, experiments and procedures more efficiently and effectively than with traditional paper lab notebooks.

Discovery Notebook is one of a series of Symyx Software offerings which include electronic lab notebook (ELN) applications tailored to meet the specific needs and protocols of chemists in the discovery, process, analytical, formulations and bioprocess functions. The latest version of Discovery Notebook features an easy-to-use interface for single and parallel experimentation, an advanced software developer kit (SDK), extensive searching and browsing capabilities and a pre-loaded reaction template database containing 30,000 transformations.

“This new version of our Discovery Notebook represents the successful integration of several key acquisitions that Symyx has made,” said Paul Nowak, chief operating officer of Symyx Technologies. “This product is uniquely designed to integrate easily into users’ existing systems so they can leverage their current resources, allowing for increased productivity, enabling better data collection and use, and providing more opportunities to make breakthrough discoveries. Our reaction template database ensures that scientists are able to get value right away from Symyx Software, without having to wait one to two years, the typical time it takes before a company’s internal database reaches critical mass.”

Discovery Notebook version 4.0 features enhanced searching and browsing capabilities. Utilizing a multi-variable search window the new version includes a powerful search panel that allows scientists to search within sets of prior results and a multi-panel layout eases browsing through experiment data. New usability enhancements include improved scientifically accurate calculator capabilities, drag and drop functionality, icon-based entry for facile data capture and additional experiment property tabs that allow users to capture and configure experiment metadata. Another key new feature of version 4.0 is the inclusion of a software developer kit that allows organizations to create custom forms such as a registration interface.

The Discovery Notebook is one software solution in a family of Symyx Electronic Lab Notebooks. Symyx ELN software features specialized, application-specific interfaces to support discovery, process, analytical, formulations and bioprocess functions. The Symyx Discovery Notebook is designed to enable chemists to use prior experience, develop new methods, access relevant information and integrate into critical systems to be more efficient and effective.

Discovery Notebook 4.0 is based on the Symyx Vault ELN document management platform, also used in other Symyx notebook products. Symyx Vault provides a single, comprehensive platform for ELN documents that can span the entire R&D organization, supporting document browsing and searching, enterprise-level security and auditing, and configurable and highly flexible document workflow. Discovery Notebook version 4.0 is now available for deployment.

Discovery E-Lab Notebook

Symyx

Plan, execute, record, and search single and parallel synthetic chemistry experimentsSymyx Discovery Notebook is an Electronic Laboratory Notebook (ELN) specifically designed to enable pharmaceutically focused discovery chemists to use prior experience, develop new methods, access relevant information, and integrate to critical systems to be more efficient and effective. Prepare: Access information from multiple sources and plan the reactions: • Search for experiments providing similar products or reactions to utilize the knowledge and expertise of one’s colleagues. • Access and incorporate the structures and data from corporate and external sources ( e.g., reagent inventory, registry). • Compute quantities and identify reactants and products (calculate stoichiometry, scale reactions, uniquely label products for analysis, attach analyses). Document: Simplify entry of observations and generate report for meetings or archives:• Utilize common and customized phrases and materials to improve the speed and accuracy of entry. • Incorporate keywords, defined properties, and safety information to classify and find relevant experiments. • Associate analytical data appropriately to procedures, products, and reactions. • Collect experiments into a single report to present design and discuss progress. Analyze: Evaluate which reaction paths are effective • Compare experiments to determine conditions or materials that caused signficant change. • Show relationships of how materials were created and used through Symyx’s unique Reaction Relay visualization capability. • Evaluate multiple pathways with the respective yields to a desired material through Retrosynthetic Analysis visualization.

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Data AnalysisData analysis hardware and software is available to make data processing straight-forward yet powerful. Data software can be used for math and stats, technical graphing and image analysis. In addition, software is available for specific data analysis of electrophoresis, densitometry, ELISA and DNA sequencing.Integration ServicesIncorporate lab systems, software and equipment with integration services.Medicinal ChemistryMedicinal chemistry is a broad discipline encompassing the design, identification, synthesis and development of chemicals in drug discovery. It includes a number of techniques covering structural biology, synthetic chemistry and molecular biology. Technologies used in medicinal chemistry include ADME, lab-on-a-chip, high content screening and assay assembly.Process ChemistryProcess chemistry is an important stage of drug development for scaling-up drug production or chemical synthesis reactions. It is useful for optimizing economical and efficient drug production. Process chemistry uses reactors and pump systems as well as reagents, standards and buffers.Electronic Laboratory NotebooksElectronic Laboratory Notebooks (ELNs) are becoming increasingly popular for documenting experimental processes and for lab data management. An ELN is informatics software which can be biology specific, chemistry specific, cross-disciplinary or web-based. Advantages of an electronic lab notebook include increased data protection, efficiency and straightforward data searching and sharing.